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Multi-Wavelength, Depth Resolved, Scattering and Pathlength Corrected in-vivo Near-Infrared Spectroscopy of Brain Tissue

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Abstract

For resolving concentrations of tissue chromophores in the human adult brain with near-infrared spectroscopy it is advantageous to calculate the light scattering and absorption, at multiple wavelengths with some depth resolution. We report a novel methodology that combines multi-distance frequency and broadband spectrometers and we show preliminary results in a healthy young adult during hypo- and hypercapnia.

© 2010 Optical Society of America

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