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Spatial frequency shift super-resolution imaging based on quasiperiodic grating and deep learning

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Abstract

In this study, we propose a pioneering spatially frequency-shifted super-resolution microscopy technique that utilizes the synergy of quasiperiodic gratings and deep learning. First, a quasiperiodic grating capable of converting evanescent waves into propagating waves is designed. The grating is positioned between the object under investigation and the objective lens, and the high-frequency information carried by the evanescent waves in the near-field region of the object is shifted into the detection window and becomes accessible in the far field for imaging. Subsequently, we provide two deep learning models for image and video reconstructions to achieve the reconstruction of static and dynamic samples respectively. Simulation results demonstrate the high feasibility of the proposed method, and both static and dynamic objects with sub-wavelength features can be resolved. The developed method paves the way to the realization of super-resolution imaging by using a traditional bright-field microscope without the need for an extensive optical system design.

© 2023 Optica Publishing Group

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Corrections

23 December 2023: Typographical corrections were made to the references.


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Supplementary Material (1)

NameDescription
Supplement 1       Part of the code and the result

Data availability

We will make public all deep learning codes, image processing scripts, and the test set used for demonstration. Additional explanations about the experiments can be found at [25].

25. X. Y. Liu, “Super-resolution-microscopy,” GitHub (2023) [accessed 19 December 2023] https://github.com/LiuXingYumeteor/Super-resolution-microscopy.

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