Abstract

In this Letter, we propose, to the best of our knowledge, the first in-fiber optofluidic Raman surface-enhanced Raman spectroscopy (SERS) sensor based on a microstructured hollow fiber (MHF) with a suspended core. Taking advantage of the unique internal structure, we immobilize silver nanoparticles with an SERS effect in the MHF by chemical bonding. The Raman signal of the microfluidic sample is excited by the excitation light in the suspended core through an evanescent field. Then the online SERS signal can be coupled back into the core and detected. To demonstrate the feasibility of the device, rhodamine 6G is chosen as the analyte, and high-quality SERS spectra are detected with the limit of detection of 1×1014M. Furthermore, an online optofluidic test is conducted on ceftriaxone (C18H18N8O7S3) to examine its capabilities in antibiotic sensing. The results show that the LOD of the samples is 106M. Significantly, this Letter provides an integrated optofluidic in-fiber SERS sensor with a microchannel that can be integrated with chip devices without spatial optical coupling, which has a broad application in medicine and food safety, as well as various aspects of biological in-fiber sensing.

© 2019 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Micro-lensed optical fibers for a surface-enhanced Raman scattering sensing probe

Karolina Milenko, Silje S. Fuglerud, Snorre B. Kjeldby, Reinold Ellingsen, Astrid Aksnes, and Dag R. Hjelme
Opt. Lett. 43(24) 6029-6032 (2018)

Fiber optic surface plasmon resonance sensor based on a silver-coated large-core suspended-core fiber

Xian Zhang, Xiao-Song Zhu, and Yi-Wei Shi
Opt. Lett. 44(18) 4550-4553 (2019)

High-sensitivity molecular sensing using hollow-core photonic crystal fiber and surface-enhanced Raman scattering

Xuan Yang, Chao Shi, Damon Wheeler, Rebecca Newhouse, Bin Chen, Jin Z. Zhang, and Claire Gu
J. Opt. Soc. Am. A 27(5) 977-984 (2010)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (7)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (1)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription