Abstract

Fourier ptychographic microscopy (FPM) is a recently proposed computational imaging method that achieves both high resolution (HR) and wide field of view. In the FPM framework, a series of low-resolution (LR) images at different illumination angles is used for high-resolution image reconstruction. On the basis of previous research, image noise can significantly degrade the FPM reconstruction result. Since the captured LR images contain a lot of dark-field images with low signal-to-noise ratio, it is very important to apply a noise-reduction process to the FPM raw dataset. However, the thresholding method commonly used for the FPM data preprocessing cannot separate signals from background noise effectively. In this work, we propose an improved thresholding method that provides a reliable background-noise threshold for noise reduction. Experimental results show that the proposed method is more efficient and robust than the conventional thresholding method.

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Other (22)

G. Zheng, R. Horstmeyer, and C. YangWide-field, high-resolution Fourier ptychographic microscopyNat. Photonics20137739745

A. Greenbaum, W. Luo, T. W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. OzcanImaging without lenses: achievements and remaining challenges of wide-field on-chip microscopyNat. Methods20129889895

L. Tian and L. Waller3D intensity and phase imaging from light field measurements in an LED array microscopeOptica20152104111

S. Dong, R. Shiradkar, P. Nanda, and G. ZhengSpectralmultiplexing and coherent-state decomposition in Fourier ptychographic imagingBiomed. Opt. Express2014517571767

L. Tian, X. Li, K. Ramchandran, and L. WallerMultiplexed coded illumination for Fourier ptychography with an LED array microscopeBiomed. Opt. Express2014523762389

M. Wang, Y. Zhang, Q. Chen, J. Sun, Y. Fan, and C. ZuoA color-corrected strategy for information multiplexed Fourier ptychographic imagingOpt. Commun.2017405406411

R. Horstmeyer, J. Chung, X. Ou, G. Zheng, and C. YangDiffraction tomography with Fourier ptychographyOptica20163827835

J. Chung, J. Kim, X. Ou, R. Horstmeyer, and C. YangWide field-of-view fluorescence image deconvolution with aberration-estimation from Fourier ptychographyBiomed. Opt. Express20167352368

S. Dong, P. Nanda, R. Shiradkar, K. Guo, and G. ZhengHigh-resolution fluorescence imaging via pattern-illuminated Fourier ptychographyOpt. Express2014222085620870

R. Horstmeyer, X. Ou, G. Zheng, P. Willems, and C. YangDigital pathology with Fourier ptychographyComput Med. Imaging Graph.2015423843

L. Tian, Z. Liu, L.-H. Yeh, M. Chen, J. Zhong, and L. WallerComputational illumination for high-speed in vitro Fourier ptychographic microscopyOptica20152904911

L.-H. Yeh, J. Dong, J. Zhong, L. Tian, M. Chen, G. Tang, M. Soltanolkotabi, and L. WallerExperimental robustness of Fourier ptychography phase retrieval algorithmsOpt. Express2015233321433240

X . Ou, G. Zheng, and C. YangEmbedded pupil function recovery for Fourier ptychographic microscopy: erratumOpt. Express2015233302733027

L. Bian, J. Suo, G. Zheng, K. Guo, F. Chen, and Q. DaiFourier ptychographic reconstruction using Wirtinger flow optimizationOpt. Express20152348564866

L. Bian, J. Suo, J. Chung, X. Ou, C. Yang, F. Chen, and Q. DaiFourier ptychographic reconstruction using Poisson maximum likelihood and truncated Wirtinger gradientSci. Rep.2016627384

C. Zuo, J. Sun, and Q. ChenAdaptive step-size strategy for noise-robust Fourier ptychographic microscopyOpt. Express2016242072420744

M. Sicairos and J. FienupPhase retrieval with transverse translation diversity: a nonlinear optimization approachOpt. Express20081672647278

X. Ou, R. Horstmeyer, C. Yang, and G. ZhengQuantitative phase imaging via Fourier ptychographic microscopyOpt. Lett.20133848454848

Z. Huang, J. Bai, T. Lu, and X. HouStray light analysis and suppression of panoramic annular lensOpt. Express2013211081010820

S. Thurman and J. FienupPhase retrieval with signal biasJ. Opt. Soc. Am. A20092610081014

P. Thibault and M. SicairosMaximum-likelihood refinement for coherent diffractive imagingNew J. Phys.201214063004

P. Godard, M. Allain, V. Chamard, and J. RodenburgNoise models for low counting rate coherent diffraction imagingOpt. Express2012202591425934

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