Abstract
The Raman spectra of six polymorphic crystal forms of <i>N</i>-cyano-<i>N'</i>-methyl-<i>N"</i>-{2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl}-guanidine (Cimetidine) have been studied to investigate the possibility of quantitative analysis of polymorphic mixtures. Characteristic Raman bands of the various polymorphs have been found, some of which proved to be appropriate for quantitative analysis. The applicability of various mathematical techniques has been investigated, of which partial least-squares (PLS) has been found to be the best.
PDF Article
More Like This
Remote Raman spectroscopy of natural rocks
Genesis Berlanga, Tayro E. Acosta-Maeda, Shiv K. Sharma, John N. Porter, Przemyslaw Dera, Hannah Shelton, G. Jeffrey Taylor, and Anupam K. Misra
Appl. Opt. 58(32) 8971-8980 (2019)
Cited By
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Login to access Optica Member Subscription