Abstract

Super-resolution imaging holds a solid place in biological and chemical sciences, but many new developments allow the beating of diffraction (Rayleigh) limit in better and more subtle ways. The modern understanding of the Rayleigh limit comes from information theory where it is identified as vanishing information about the separation of two sources for small separations - the Rayleigh curse. The surprising observation [1] that the quantum Cramer-Rao bound (CRB), which identifies maximum information available in the optical field, does not vanish even for zero separation, led to so-called quantum-inspired superresolution methods that suggest to fully exploit information already present in the field by performing tailored measurements [1]. Such an approach is starkly different approach compared with methods relying on nonlinear processes such as STED or specific emission statistics.

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