Abstract

Phase-preserving spectral estimation optical coherence tomography (SE-OCT) enables combining axial resolution improvement with computational depth of focus (DOF) extension. We combine SE-OCT with interferometric synthetic aperture microscopy (ISAM) to obtain a high 3D resolution over a large depth range with a narrow bandwidth visible light super-luminescent diode (SLD). SE-OCT gives a five times axial resolution improvement to 1.5 micrometer. The combination with ISAM gives a sub-micron lateral resolution over a 300 micrometer axial range, 12 times the conventional DOF. The results show that phase-preserving SE-OCT is sufficiently accurate for coherent post-processing, enabling the use of cost-effective SLDs in the visible light range for high spatial resolution OCT.

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