Abstract
Near-infrared optical tomography (NIROT) is a non-invasive imaging technique based on diffuse propagation of light in turbid media. It has high sensitivity to tissue oxygenation, which is a vital biomarker. NIROT enables one to quantify and image oxygenation at a bed-side in clinics, thus complementing other imaging modalities. Time-domain (TD) NIROT systems benefit from time-of-flight (ToF) information, but are often affected by relatively low signal-to-noise ratio and long acquisition time. However, fast acquisition is needed for in vivo assessment of oxygenation. In this work we present a time-multiplexing approach which enables multiple-fold faster acquisition with high SNR, suitable for various ToF applications, including NIROT. We combine it with hybrid convolutional neural-network (hCNN) -enhanced reconstruction to achieve an impressive 11-fold increase in acquisition speed.
© 2023 SPIE
PDF ArticleMore Like This
Jingjing Jiang, Aldo di Costanzo, Scott Lindner, Martin Wolf, and Alexander Kalyanov
JTu3A.18 Clinical and Translational Biophotonics (Translational) 2020
Vamshi Damagatla, Nadia G. Boetti, Laura Di Sieno, Diego Pugliese, Davide Janner, Alberto Dalla Mora, and Antonio Pifferi
1262818 European Conference on Biomedical Optics (ECBO) 2023
Meghdoot Mozumder, Jarkko Leskinen, and Tanja Tarvainen
1262820 European Conference on Biomedical Optics (ECBO) 2023