Abstract
The use of zero-mode waveguides - photonic observation volume confinement nanostructures – and instrumentation is described for allowing single-molecule, real-time biomolecular analysis, with biotechnological applications such as rapid DNA sequencing.
© 2011 Optical Society of America
PDF ArticleMore Like This
Zero-mode Waveguides for Single Molecule Analysis and Fast DNA Sequencing
Michael Levene, Jonas Korlach, Stephen Turner, Harold G. Craighead, and Watt W. Webb
CWJ4 Conference on Lasers and Electro-Optics (CLEO:S&I) 2002
Micro- and nanofluidics for single biomolecule analysis
Yoshinobu Baba
LSTuF4 Laser Science (LS) 2009
The Electrostatic Corral: Trapping Single DNA Molecules in Solution
Christine A. Carlson and Jorg C. Woehl
OTMC5 Optical Trapping Applications (OMA) 2011