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Speed-enhanced scattering compensation method with sub-Nyquist sampling

Zhenghan Li, Jiazhu Zhu, Wei Gong, and Ke Si

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Abstract

A rapid feedback-based scattering compensation method is particularly important for guiding light precisely within turbid tissues, especially the dynamic tissues. However, the huge number of measurements that come from the underutilization of the signal frequency channel greatly limits the modulation speed. This paper introduces a rapid compensation method with the sub-Nyquist sampling which improves the channel utilization and the speed of wavefront shaping. The number of measurements is reduced to ∼1500 with 32 × 32 freedom, and the PBR of the focus reaches ∼200. The system performances are demonstrated by focusing the light through brain slices of different thicknesses.

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Data underlying the results presented in this Letter are not publicly available at this time but may be obtained from the authors upon reasonable request.

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