Abstract

Elastography is a technique that measures and maps the local elastic property of biological tissues. Aiming for detection of micron-scale inclusions, various optical elastography, especially optical coherence elastography (OCE), techniques have been investigated over the past decade. The challenges of current optical elastography methods include the decrease in elastographic resolution as compared with its parent imaging resolution, the detection sensitivity and accuracy, and the cost of the overall system. Here we report for the first time, we believe, on an elastography technique—crawling wave optical coherence elastography (CRW-OCE)—which significantly lowers the requirements on the imaging speed and opens the path to high-resolution and high-sensitivity OCE at relatively low cost. Methods of crawling wave excitation, data acquisition, and crawling wave tracking are presented.

© 2016 Optical Society of America

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Supplementary Material (2)

NameDescription
» Visualization 1: AVI (6929 KB)      A movie shows series of Doppler images captured by our phased resolved Doppler OCT, which clearly shows the different speed of the crawling wave in the two regions.
» Visualization 2: AVI (3369 KB)      A movie shows propagation of the crawling wave envelop across 10 mm lateral distance at around the boundary between the two concentrations of the gelatin phantom.

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