Approach to fiber-based optical polarimetry for tissue assessment: system calibration and application

Mahima Sharma; Chitra Shaji; Sujatha Narayanan Unni

doi:10.1364/AO.501447

Applied Optics
Vol. 63,
Issue 8,
pp. 1888-1894
(2024)
•https://doi.org/10.1364/AO.501447

Approach to fiber-based optical polarimetry for tissue assessment: system calibration and application

Mahima Sharma, Chitra Shaji, and Sujatha Narayanan Unni

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Mahima Sharma, Chitra Shaji, and Sujatha Narayanan Unni, "Approach to fiber-based optical polarimetry for tissue assessment: system calibration and application," Appl. Opt. 63, 1888-1894 (2024)

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Table of Contents Category
- Instrumentation and Measurements
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The topics in this list come from the Optics and Photonics Topics applied to this article.

About this Article
History
- Original Manuscript: September 13, 2023
- Revised Manuscript: January 30, 2024
- Manuscript Accepted: February 4, 2024
- Published: March 4, 2024

Abstract

The potential of optical polarimetry is increasingly explored to unravel the tissue structure through several optical instrument configurations. Fiber-based solutions offer portability and are accommodative in an endoscopic examination environment. Here, we address the challenges in realizing a fiber-based optical polarimetry system through an approach involving an all-fiber polarization controller. The methods of device calibration and application in bulk tissues are discussed, and results are presented.

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The data supporting this study’s findings are available from the corresponding author upon reasonable request.

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	Waveplate Voltages (Volt)			Polarization Orientation	Measured Input Stokes Vector				Computed
S.No	WP1	WP2	WP3	(Close Approximation)	$s_{1}$	$s_{2}$	$s_{3}$	$s_{4}$	DOP
(i)	3.67	0	0	Horizontal (H)	1	0.965	−0.046	0.210	0.99
(ii)	1.80	0	0	Diagonal −45° (M)	1	−0.013	−0.936	−0.175	0.95
(iii)	6.98	0	0	Right circular (R)	1	0.089	−0.078	0.970	0.97
(iv)	3.67	3.41	2.29	Vertical (V)	1	−0.965	0.074	−0.235	0.99

	Waveplate Voltages (Volt)			Polarization Orientation	Measured Input Stokes Vector				Computed
S.No	WP1	WP2	WP3	(Close Approximation)	$s_{1}$	$s_{2}$	$s_{3}$	$s_{4}$	DOP
Or	3.67	0	0	Horizontal (H)	1	0.952	−0.050	0.250	0.98
(ii)	1.80	0	0	Diagonal −45° (M)	1	−0.151	0.935	0.112	0.95
(iii)	6.98	0	0	Right circular (R)	1	0.001	−0.313	−0.892	0.94
(iv)	3.67	2.54	2.10	Vertical (V)	1	−0.981	−0.191	0.005	0.99

	Transmission					Reflection
S. No.	$s_{1}$	$s_{2}$	$s_{3}$	$s_{4}$	DOP	$s_{1}$	$s_{2}$	$s_{3}$	$s_{4}$	DOP
(i)	1	−0.015	−0.980	0.110	0.99	1	0.047	0.979	−0.097	0.99
(ii)	1	0.020	−0.980	0.080	0.99	1	0.0648	0.988	−0.136	0.97
(iii)	1	0.006	−0.980	0.100	0.99	1	0.0758	0.971	−0.103	0.98
(iv)	1	0.002	−0.984	−0.022	0.98	1	0.0117	0.974	−0.139	0.98

	Normalized Stokes Vectors
Sample	$s_{1}$	$s_{2}$	$s_{3}$	$s_{4}$	DOP
Normal colon	$1 \pm 0$	$0.0067 \pm 0.002$	$0.022 \pm 0.02$	$- 0.284 \pm 0.019$	$0.285 \pm 0.017$
Cancerous colon	$1 \pm 0$	$0.011 \pm 0.007$	$0.007 \pm 0.008$	$- 0.35 \pm 0.016$	$0.354 \pm 0.016$

	Waveplate Voltages (Volt)			Polarization Orientation	Measured Input Stokes Vector				Computed
S.No	WP1	WP2	WP3	(Close Approximation)	$s_{1}$	$s_{2}$	$s_{3}$	$s_{4}$	DOP
(i)	3.67	0	0	Horizontal (H)	1	0.965	−0.046	0.210	0.99
(ii)	1.80	0	0	Diagonal −45° (M)	1	−0.013	−0.936	−0.175	0.95
(iii)	6.98	0	0	Right circular (R)	1	0.089	−0.078	0.970	0.97
(iv)	3.67	3.41	2.29	Vertical (V)	1	−0.965	0.074	−0.235	0.99

Abstract

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Figures (3)

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Equations (3)

Applied Optics