Numerical method for studying the detectability of inclusions hidden in optically turbid tissue

Abstract

We introduce an efficient numerical method for studying the detectability of absorptive inclusions in a multiple-scattering optical medium. Use of the method is demonstrated by the forward calculation of integrated and time-gated photon intensities. Schemes for positioning the light source above an inclusion and otherwise determining the location of a hidden object, involving either reflected or transmitted reemissions, are discussed as examples. They are investigated for several illustrative models, and images are calculated as a function of the size and shape of the inclusion.

© 1993 Optical Society of America

Scaling relationships for theories of anisotropic random walks applied to tissue optics

A. H. Gandjbakhche, R. Nossal, and R. F. Bonner
Appl. Opt. 32(4) 504-516 (1993)

Real time optical method for localization of inclusions embedded in turbid media

Anabela Da Silva, Nadia Djaker, Nicolas Ducros, Jean-Marc Dinten, and Philippe Rizo
Opt. Express 18(8) 7753-7762 (2010)

Absorptivity contrast in transillumination imaging of tissue abnormalities

A. H. Gandjbakhche, R. F. Bonner, R. Nossal, and G. H. Weiss
Appl. Opt. 35(10) 1767-1774 (1996)

Diffuse reflectance from turbid media: an analytical model of photon migration

Jun Wu, Firooz Partovi, Michael S. Field, and Richard P. Rava
Appl. Opt. 32(7) 1115-1121 (1993)

Statistical detection and imaging of objects hidden in turbid media using ballistic photons

Sina Farsiu, James Christofferson, Brian Eriksson, Peyman Milanfar, Benjamin Friedlander, Ali Shakouri, and Robert Nowak
Appl. Opt. 46(23) 5805-5822 (2007)