Abstract
Breast cancer is a leading cause of death in women and has scope for improvement in treatment stratification. We report the use of high contrast UCNP staining to distinguish different levels of HER2 expression in HER2 analyte control and HER2-positive breast cancer tissue biopsies. A contrast of 40 was found as compared to the negative control and 25 as compared to conventional DAB staining.
© 2022 The Author(s)
PDF ArticleMore Like This
Sanathana Konugolu Venkata Sekar, Hui Ma, Katarzyna Komolibus, Gokhan Dumlupinar, Matthias J. Mickert, Krzysztof Krawczyk, and Stefan Andersson-Engels
JTu5A.87 Frontiers in Optics (FiO) 2023
Maria Navas-Moreno, Tatyana Chernenko, Majid Mehrpouyen, Ming Yan, Demet Candas, Jian Jian Li, and James W. Chan
BT4A.5 Bio-Optics: Design and Application (BODA) 2015
Nimmi Ramanujam
BMA4 Biomedical Optics (BIOMED) 2008