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Optica Publishing Group
  • Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)
  • Technical Digest Series (Optica Publishing Group, 2023),
  • paper OM2E.2
  • https://doi.org/10.1364/OMP.2023.OM2E.2

Fluorescence Lifetime Imaging of NADH and FAD in Ex Vivo Young and Old Mouse Cortical Tissue

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Abstract

Young and old murine cortical tissue in fresh, snap frozen, and DMSO-preserved form were investigated with two-photon microscopy. Shorter mean NADH and FAD lifetimes were found in old cortical tissue compared to young.

© 2023 The Author(s)

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More Like This
Unveiling metabolic changes in ex vivo brain tissue through intrinsic NADH autofluorescence imaging using the advanced non-linear optical modality

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