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Detecting Cancer Cells Labeled With Gold Nanorods Using Nonlinear Endomicroscopy

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Abstract

Gold Nanorods are used to specifically label cancer cells. Cervical cancer cells, HeLa cells, labeled by gold nanorods were first detected by multi-photon-excited photoluminescence endomicroscopy, which shows that multi-photon-excited photoluminescence endomicroscopy could be used in noninvasively detecting cancers. Furthermore, cells labelled with gold nanorods become highly susceptible to photothermal damage when irradiated at the plasmon resonance. Therefore multi-photon-excited photoluminescence endomicroscopy is potential for cancer cells or tumors therapy and treatment.

© 2009 Optical Society of America

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