Abstract

Registration, or alignment, of retinal images taken at different times is frequently required in image-processing applications. Images that need to be registered may be separated by a few years and may show slow changes in the retina. Such changes include drusen, nerve fiber layer damage, and changes in optic disc cupping and pallor. Registration may also be required for pictures taken only a fraction of a second apart, as in measurement of dilution curves in fluorescein angiography or at video rates required in fundus perimetry using the scanning laser ophthalmoscope (SLO).

© 1987 Optical Society of America