Bulk Optical Properties of Normal Breasts and Tissue Phantoms Obtained with Clinical Optical Imager

Turgut Durduran; J. P. Culver; L. Zubkov; R. Choe; M. Holboke; D. N. Pattanayak; B. Chance; B. Chance; A. G. Yodh

doi:10.1364/IVOI.1999.DIS130

Proceedings of Inter-Institute Workshop on In Vivo Optical Imaging at the NIH
Technical Digest Series (Optica Publishing Group, 1999),
paper DIS130
•https://doi.org/10.1364/IVOI.1999.DIS130

Bulk Optical Properties of Normal Breasts and Tissue Phantoms Obtained with Clinical Optical Imager

Turgut Durduran, J. P. Culver, L. Zubkov, R. Choe, M. Holboke, D. N. Pattanayak, B. Chance, and A. G. Yodh

In Vivo optical Imaging at the NIH 1999

Bethesda, MD United States
16–17 September 1999
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Diffuse Imaging and Spectroscopy (DIS)

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T. Durduran, J. P. Culver, L. Zubkov, R. Choe, M. Holboke, D. N. Pattanayak, B. Chance, and A. G. Yodh, "Bulk Optical Properties of Normal Breasts and Tissue Phantoms Obtained with Clinical Optical Imager," in Proceedings of Inter-Institute Workshop on In Vivo Optical Imaging at the NIH, Technical Digest Series (Optica Publishing Group, 1999), paper DIS130.

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Abstract

A clinical diffuse optical imager in the compressed breast geometry is used to determine the bulk optical properties and blood saturation in breast tissue of volunteers. We use a finite difference based forward model for the estimation of bulk tissue optical properties. The method is tested on tissue phantoms made of balloons and Intralipid, and is then applied in-vivo. Careful modeling of the chest wall was found to be critical for optical property determination.

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