Abstract

Optical coherence tomography (OCT) is a well-established modality for structural and functional imaging of the biological samples. Conventional scanning OCT combines the low temporal coherence with confocal gating to reject multiply scattered light. However, OCT uses a spatially coherent light source, and thus, is susceptible to speckle noise, which reduces the transverse resolution. We use dynamic light scattering to improve the transverse resolution. The dynamic scattering particles induce speckles, that change over time due to particle displacement. By incoherently averaging OCT images acquired under different particle distributions, we effectively suppress the spatial coherence and improve transverse image resolution.

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