Abstract
Cancer is one of the leading causes for morbidity and mortality worldwide. Therefore, efforts are concentrated on cancer detection in an early stage to enhance survival rates for cancer patients. A certain intraoperative navigation in the tumor border zone is also an essential task to lower the mortality rate after surgical treatment. Molecular spectroscopy methods proved to be powerful tools to differentiate cancerous and healthy tissue. Within our project comparison of different vibration spectroscopy methods were tested to select the better one or to reach synergy from their combination.
One key aspect was in special fiber probe development for each technique. Using fiber optic probes in Raman, MIR and NIR spectroscopy is a very powerful method for non-invasive in vivo applications. Miniaturization of Raman probes was achieved by deposition of dielectric filters directly onto the silica fiber end surfaces. Raman, NIR and MIR spectroscopy were used to analyze samples from kidney tumors. The differentiation between cancer and healthy samples was successfully obtained by multivariate data analysis.
© 2015 SPIE
PDF ArticleMore Like This
V. Artyushenko, U. Zabarylo, A. Bogomolov, O. Minet, H. Krause, T. Sakharova, I. Usenov, F. Schulte, and H.J. Eichler
JTu3A.11 Cancer Imaging and Therapy (Cancer) 2016
Siddra Maryam, M Daniyal Ghauri, Edward Fahy, Sanathana Konugolu Venkata Sekar, Marcelo Saito Nogueira, Huihui Lu, Alida Russo, Ray Burke, Linda Feeley, Patrick Sheahan, Richeal Ni Riordain, Stefan Andersson-Engels, Kiang Wei Kho, and Rekha Gautam
126270B European Conference on Biomedical Optics (ECBO) 2023
Riccardo Cicchi, Suresh Anand, Alfonso Crisci, Flavio Giordano, Susanna Rossari, Vincenzo De Giorgi, Vincenza Maio, Daniela Massi, Gabriella Nesi, Anna Maria Buccoliero, Renzo Guerrini, Nicola Pimpinelli, and Francesco Saverio Pavone
95370I European Conference on Biomedical Optics (ECBO) 2015