Fluorescence Lifetime Sensing with Two-Photon Interferometry

Ashley Lyons; Vytautas Zickus; Vytautas Zickus; Raul Alvarez-Mendoza; Danilo Triggiani; Vincenzo Tamma; Manlio Tassieri; Daniele Faccio

doi:10.1364/COSI.2023.CM3B.3

Optica Imaging Congress (3D, COSI, DH, FLatOptics, IS, pcAOP)
Technical Digest Series (Optica Publishing Group, 2023),
paper CM3B.3
•https://doi.org/10.1364/COSI.2023.CM3B.3

Fluorescence Lifetime Sensing with Two-Photon Interferometry

Ashley Lyons, Vytautas Zickus, Raul Alvarez-Mendoza, Danilo Triggiani, Vincenzo Tamma, Manlio Tassieri, and Daniele Faccio

Computational Optical Sensing and Imaging 2023

Boston, Massachusetts United States
14–17 August 2023
ISBN: 978-1-957171-28-9

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Computational Wide Field Microscopy (CM3B)

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A. Lyons, V. Zickus, R. Alvarez-Mendoza, D. Triggiani, V. Tamma, M. Tassieri, and D. Faccio, "Fluorescence Lifetime Sensing with Two-Photon Interferometry," in Optica Imaging Congress (3D, COSI, DH, FLatOptics, IS, pcAOP), Technical Digest Series (Optica Publishing Group, 2023), paper CM3B.3.

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Abstract

The temporal resolution of fluorescence lifetime microscopy is typically restricted to 100s picoseconds due to detector response. We present a novel technique, inspired by quantum interferometry, that is limited only by the optical pulse duration.

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