All-in-one confocal and widefield fluorescence microscope to investigate membrane receptor dynamics

M. Bathe-Peters; P. Gmach; P. Annibale; M. J. Lohse

doi:10.1364/COSI.2019.JW2A.4

Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP)
OSA Technical Digest (Optica Publishing Group, 2019),
paper JW2A.4
•https://doi.org/10.1364/COSI.2019.JW2A.4

All-in-one confocal and widefield fluorescence microscope to investigate membrane receptor dynamics

M. Bathe-Peters, P. Gmach, P. Annibale, and M. J. Lohse

Computational Optical Sensing and Imaging 2019

Munich Germany
24–27 June 2019
ISBN: 978-1-943580-63-7

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M. Bathe-Peters, P. Gmach, P. Annibale, and M. J. Lohse, "All-in-one confocal and widefield fluorescence microscope to investigate membrane receptor dynamics," in Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP), OSA Technical Digest (Optica Publishing Group, 2019), paper JW2A.4.

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Abstract

We present the setup of a fluorescence microscope combining TIRF and confocal microscopy within one body to address multi-scale dynamics of GPCRs on plasma membranes of living cells with adequate spatial and temporal resolution.

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