Coherent Raman imaging by means of coherent anti-Stokes Raman scattering (CARS) or stimulated Raman scattering (SRS) have been promoted from almost two decades now as efficient label free fast imaging modalities with chemical sensitivity and with a sensitivity orders of magnitude greater than spontaneous Raman scattering . The ability of CARS to detect stable isotope (e.g. deuterium and C13) is appealing since these tiny vibrational probes only differ from their natural counterparts by neutron numbers and thus closely mimic the corresponding physicochemical properties. Recently we have used deuterated molecular compounds to follow how active molecules penetrate into human skin  and revealed 3D trans-cutaneous molecular diffusion pathways with important applications in dermatology .
© 2017 IEEEPDF Article
More Like This
jsii_1_1 European Quantum Electronics Conference (EQEC) 2019
Keigo Hirose, Shuichiro Fukushima, Taichi Furukawa, and Mamoru Hashimoto
5p_A409_8 JSAP-OSA Joint Symposia (JSAP) 2017
Sam Osseiran, Hequn Wang, Victoria Fang, Joachim Pruessner, Luke Funk, and Conor L. Evans
NS2C.3 Novel Techniques in Microscopy (NTM) 2017