Abstract

We address the problem of three-dimensional optical imaging of mesoscopic systems. These are systems of intermediate optical thickness, where the photon mean free path is of the order of the system size. In this case, light exhibits sufficiently strong scattering so that the image reconstruction methods of computed tomography are not applicable, yet the detected light is not diffuse and the diffuse tomography can not be employed either. On the mesoscopic length scale, applications to biological systems include imagining of engineered tissues, semitransparent organisms, or superficial tissues.

© 2009 IEEE