Abstract

Light scattering by tissues limits performance in biological sensing or stimulation. Here we present a photoacoustic technique that increases light transmittance by one order of magnitude and enables light localization in deep tissue. Laser-induced nonlinear acoustic waves are utilized to produce a high refractive index contrast in scattering medium without high-intensity pressure. The size of guiding area is around 60 μm, which is equivalent or smaller than the diameter of multimode fibers. To show potential use in biomedical fields, we performed light guiding and imaging of fluorescence, through swine tissues with thickness more than 1 mm.

© 2019 Optical Society of America

Full Article  |  PDF Article
More Like This
High-speed photoacoustic-guided wavefront shaping for focusing light in scattering media

Tianrui Zhao, Sebastien Ourselin, Tom Vercauteren, and Wenfeng Xia
Opt. Lett. 46(5) 1165-1168 (2021)

High-resolution photoacoustic endoscope through beam self-cleaning in a graded index fiber

Yi Zhang, Yingchun Cao, and Ji-Xin Cheng
Opt. Lett. 44(15) 3841-3844 (2019)

Simultaneous photoacoustic imaging of intravascular and tissue oxygenation

Maomao Chen, Hailey J. Knox, Yuqi Tang, Wei Liu, Liming Nie, Jefferson Chan, and Junjie Yao
Opt. Lett. 44(15) 3773-3776 (2019)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Supplementary Material (1)

NameDescription
» Visualization 1       Motion pictures acquired by a high-speed camera with frame interval of 200 ns, showing focusing of the acoustic wave at the sample. At T = 5.2 µs, bright spot appears with the convergence of the acoustic waves. Scale bar represents 4 µm.

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription