Abstract

In this Letter, we describe spatially switched surface plasmon microscopy (ssSPM) based on two-channel momentum sampling. The performance evaluated with periodic nanowires in comparison with conventional SPM and bright-field microscopy shows that the resolution of ssSPM is enhanced by almost 15 times over conventional SPM. ssSPM provides an extremely simple way to attain diffraction limit in SPM and to go beyond for super-resolution in label-free microscopy techniques.

© 2018 Optical Society of America

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2017 (1)

H. Yu, X. Shan, S. Wang, and N. Tao, Anal. Chem. 89, 2704 (2017).
[Crossref]

2015 (1)

W. Lee, Y. Kinosita, Y. Oh, N. Mikami, H. Yang, M. Miyata, T. Nishizaka, and D. Kim, ACS Nano 9, 10896 (2015).
[Crossref]

2014 (3)

J. Choi, K. Kim, Y. Oh, A. L. Kim, S. Y. Kim, J.-S. Shin, and D. Kim, Adv. Opt. Mater. 2, 48 (2014).
[Crossref]

K. Toma, H. Kano, and A. Offenhäusser, ACS Nano 8, 12612 (2014).
[Crossref]

L. Laplatine, L. Leroy, R. Calemczuk, D. Baganizi, P. N. Marche, Y. Roupioz, and T. Livache, Opt. Express 22, 22771 (2014).
[Crossref]

2013 (3)

O. von Olshausen and A. Rohrbach, Opt. Lett. 38, 4066 (2013).
[Crossref]

C. F. Soon, S. A. Khaghani, M. Youseffi, N. Nayan, H. Saim, S. Britland, and M. C. T. Denyer, Colloids Surf. B 110, 156 (2013).
[Crossref]

H. Shinohara, Y. Sakai, and T. A. Mir, Anal. Biochem. 441, 185 (2013).
[Crossref]

2012 (5)

W. Wang, Y. Yang, S. Wang, V. J. Nagaraj, Q. Liu, J. Wu, and N. Tao, Nat. Chem. 4, 846 (2012).
[Crossref]

K. Kim, J. Yajima, Y. Oh, W. Lee, S. Oowada, T. Nishizaka, and D. Kim, Small 8, 892 (2012).
[Crossref]

S. A. Meyer, B. Auguié, E. C. Le Ru, and P. G. Etchegoin, J. Phys. Chem. A 116, 1000 (2012).
[Crossref]

K. Watanabe, K. Matsuura, F. Kawata, K. Nagata, J. Ning, and H. Kano, Biomed. Opt. Express 3, 354 (2012).
[Crossref]

K. Watanabe, R. Miyazaki, G. Terakado, T. Okazaki, K. Morigaki, and H. Kano, Biomed. Opt. Express 3, 2012 (2012).
[Crossref]

2011 (1)

2010 (5)

D. J. Kim and D. Kim, J. Opt. Soc. Am. B 27, 1252 (2010).
[Crossref]

Y.-D. Su, K.-C. Chiu, N.-S. Chang, H.-L. Wu, and S.-J. Chen, Opt. Express 18, 20125 (2010).
[Crossref]

K. Kim, Y. Oh, W. Lee, and D. Kim, Opt. Lett. 35, 3501 (2010).
[Crossref]

X. Shan, U. Patel, S. Wang, R. Iglesias, and N. Tao, Science 327, 1363 (2010).
[Crossref]

Y. Yanase, T. Hiragun, S. Kaneko, H. J. Gould, M. W. Greaves, and M. Hide, Biosens. Bioelectron. 26, 674 (2010).
[Crossref]

2009 (2)

R. Vander and S. G. Lipson, Opt. Lett. 34, 37 (2009).
[Crossref]

A. W. Peterson, M. Halter, A. Tona, K. Bhadriraju, and A. L. Plant, BMC Cell Biol. 10, 16 (2009).
[Crossref]

2008 (3)

R. Thariani and P. Yager, Sens. Actuators B 130, 765 (2008).
[Crossref]

J. S. Yuk, J. W. Jung, Y. M. Kim, and K. S. Ha, Sens. Actuators B 129, 113 (2008).
[Crossref]

K. J. Moh, X.-C. Yuan, J. Bu, S. W. Zhu, and B. Z. Gao, Opt. Express 16, 20734 (2008).
[Crossref]

2007 (1)

B. Huang, F. Yu, and R. N. Zare, Anal. Chem. 79, 2979 (2007).
[Crossref]

2006 (1)

I. I. Smolyaninov, J. Elliott, G. Wurtz, A. V. Zayats, and C. C. Davis, Appl. Phys. B 84, 253 (2006).
[Crossref]

2003 (1)

S. Kotsev, C. Dushkin, I. Ilev, and K. Nagayama, Colloid Polym. Sci. 281, 343 (2003).
[Crossref]

2001 (3)

T. Zhang, H. Morgan, A. S. G. Curtis, and M. Riehle, J. Opt. A 3, 333 (2001).
[Crossref]

A. T. A. Jenkins, T. Neumann, and A. Offenhäusser, Langmuir 17, 265 (2001).
[Crossref]

B. Lamprecht, J. R. Krenn, G. Schider, H. Ditlbacher, M. Salerno, N. Felidj, A. Leitner, F. R. Aussenegg, and J. C. Weeber, Appl. Phys. Lett. 79, 51 (2001).
[Crossref]

2000 (1)

1999 (1)

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[Crossref]

1996 (1)

H. Knobloch, G. von Szada-Borryszkowski, S. Woigk, A. Helms, and L. Brehmer, Appl. Phys. Lett. 69, 2336 (1996).
[Crossref]

1995 (2)

D. Piscevic, W. Knoll, and M. J. Tarlov, Supramol. Sci. 2, 99 (1995).
[Crossref]

G. Flatgen, K. Krischer, B. Pettinger, and K. Doblhofer, Science 269, 668 (1995).
[Crossref]

1994 (1)

C. E. Berger, R. P. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
[Crossref]

1991 (1)

R. P. H. Kooyman and U. J. Krull, Langmuir 7, 1506 (1991).
[Crossref]

1989 (1)

W. Hickel, D. Kamp, and W. Knoll, Nature 339, 186 (1989).
[Crossref]

1988 (1)

B. Rothenhäusler and W. Knoll, Nature 332, 615 (1988).
[Crossref]

1983 (1)

B. Liedberg, C. Nylander, and I. Lunström, Sens. Actuators 4, 299 (1983).
[Crossref]

Argoul, F.

Auguié, B.

S. A. Meyer, B. Auguié, E. C. Le Ru, and P. G. Etchegoin, J. Phys. Chem. A 116, 1000 (2012).
[Crossref]

Aussenegg, F. R.

B. Lamprecht, J. R. Krenn, G. Schider, H. Ditlbacher, M. Salerno, N. Felidj, A. Leitner, F. R. Aussenegg, and J. C. Weeber, Appl. Phys. Lett. 79, 51 (2001).
[Crossref]

Baganizi, D.

Bastmeyer, M.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[Crossref]

Bechinger, C.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[Crossref]

Berger, C. E.

C. E. Berger, R. P. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
[Crossref]

Berguiga, L.

Bhadriraju, K.

A. W. Peterson, M. Halter, A. Tona, K. Bhadriraju, and A. L. Plant, BMC Cell Biol. 10, 16 (2009).
[Crossref]

Brehmer, L.

H. Knobloch, G. von Szada-Borryszkowski, S. Woigk, A. Helms, and L. Brehmer, Appl. Phys. Lett. 69, 2336 (1996).
[Crossref]

Britland, S.

C. F. Soon, S. A. Khaghani, M. Youseffi, N. Nayan, H. Saim, S. Britland, and M. C. T. Denyer, Colloids Surf. B 110, 156 (2013).
[Crossref]

Bu, J.

Calemczuk, R.

Chang, N.-S.

Chen, S.-J.

Chiu, K.-C.

Choi, I.-H.

T. Son, J. Seo, I.-H. Choi, and D. Kim, “Label-free quantification of cell-to-substrate separation by surface plasmon resonance microscopy,” Opt. Commun., submitted for publication.
[Crossref]

Choi, J.

J. Choi, K. Kim, Y. Oh, A. L. Kim, S. Y. Kim, J.-S. Shin, and D. Kim, Adv. Opt. Mater. 2, 48 (2014).
[Crossref]

Curtis, A. S. G.

T. Zhang, H. Morgan, A. S. G. Curtis, and M. Riehle, J. Opt. A 3, 333 (2001).
[Crossref]

Davis, C. C.

I. I. Smolyaninov, J. Elliott, G. Wurtz, A. V. Zayats, and C. C. Davis, Appl. Phys. B 84, 253 (2006).
[Crossref]

Denyer, M. C. T.

C. F. Soon, S. A. Khaghani, M. Youseffi, N. Nayan, H. Saim, S. Britland, and M. C. T. Denyer, Colloids Surf. B 110, 156 (2013).
[Crossref]

Ditlbacher, H.

B. Lamprecht, J. R. Krenn, G. Schider, H. Ditlbacher, M. Salerno, N. Felidj, A. Leitner, F. R. Aussenegg, and J. C. Weeber, Appl. Phys. Lett. 79, 51 (2001).
[Crossref]

Doblhofer, K.

G. Flatgen, K. Krischer, B. Pettinger, and K. Doblhofer, Science 269, 668 (1995).
[Crossref]

Dushkin, C.

S. Kotsev, C. Dushkin, I. Ilev, and K. Nagayama, Colloid Polym. Sci. 281, 343 (2003).
[Crossref]

Elezgaray, J.

Elliott, J.

I. I. Smolyaninov, J. Elliott, G. Wurtz, A. V. Zayats, and C. C. Davis, Appl. Phys. B 84, 253 (2006).
[Crossref]

Etchegoin, P. G.

S. A. Meyer, B. Auguié, E. C. Le Ru, and P. G. Etchegoin, J. Phys. Chem. A 116, 1000 (2012).
[Crossref]

Felidj, N.

B. Lamprecht, J. R. Krenn, G. Schider, H. Ditlbacher, M. Salerno, N. Felidj, A. Leitner, F. R. Aussenegg, and J. C. Weeber, Appl. Phys. Lett. 79, 51 (2001).
[Crossref]

Flatgen, G.

G. Flatgen, K. Krischer, B. Pettinger, and K. Doblhofer, Science 269, 668 (1995).
[Crossref]

Gao, B. Z.

Giebel, K.-F.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[Crossref]

Gould, H. J.

Y. Yanase, T. Hiragun, S. Kaneko, H. J. Gould, M. W. Greaves, and M. Hide, Biosens. Bioelectron. 26, 674 (2010).
[Crossref]

Greaves, M. W.

Y. Yanase, T. Hiragun, S. Kaneko, H. J. Gould, M. W. Greaves, and M. Hide, Biosens. Bioelectron. 26, 674 (2010).
[Crossref]

Greve, J.

C. E. Berger, R. P. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
[Crossref]

Ha, K. S.

J. S. Yuk, J. W. Jung, Y. M. Kim, and K. S. Ha, Sens. Actuators B 129, 113 (2008).
[Crossref]

Halter, M.

A. W. Peterson, M. Halter, A. Tona, K. Bhadriraju, and A. L. Plant, BMC Cell Biol. 10, 16 (2009).
[Crossref]

Helms, A.

H. Knobloch, G. von Szada-Borryszkowski, S. Woigk, A. Helms, and L. Brehmer, Appl. Phys. Lett. 69, 2336 (1996).
[Crossref]

Herminghaus, S.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[Crossref]

Hickel, W.

W. Hickel, D. Kamp, and W. Knoll, Nature 339, 186 (1989).
[Crossref]

Hide, M.

Y. Yanase, T. Hiragun, S. Kaneko, H. J. Gould, M. W. Greaves, and M. Hide, Biosens. Bioelectron. 26, 674 (2010).
[Crossref]

Hiragun, T.

Y. Yanase, T. Hiragun, S. Kaneko, H. J. Gould, M. W. Greaves, and M. Hide, Biosens. Bioelectron. 26, 674 (2010).
[Crossref]

Huang, B.

B. Huang, F. Yu, and R. N. Zare, Anal. Chem. 79, 2979 (2007).
[Crossref]

Iglesias, R.

X. Shan, U. Patel, S. Wang, R. Iglesias, and N. Tao, Science 327, 1363 (2010).
[Crossref]

Ilev, I.

S. Kotsev, C. Dushkin, I. Ilev, and K. Nagayama, Colloid Polym. Sci. 281, 343 (2003).
[Crossref]

Jenkins, A. T. A.

A. T. A. Jenkins, T. Neumann, and A. Offenhäusser, Langmuir 17, 265 (2001).
[Crossref]

Jung, J. W.

J. S. Yuk, J. W. Jung, Y. M. Kim, and K. S. Ha, Sens. Actuators B 129, 113 (2008).
[Crossref]

Kamp, D.

W. Hickel, D. Kamp, and W. Knoll, Nature 339, 186 (1989).
[Crossref]

Kaneko, S.

Y. Yanase, T. Hiragun, S. Kaneko, H. J. Gould, M. W. Greaves, and M. Hide, Biosens. Bioelectron. 26, 674 (2010).
[Crossref]

Kano, H.

Kawata, F.

Khaghani, S. A.

C. F. Soon, S. A. Khaghani, M. Youseffi, N. Nayan, H. Saim, S. Britland, and M. C. T. Denyer, Colloids Surf. B 110, 156 (2013).
[Crossref]

Kim, A. L.

J. Choi, K. Kim, Y. Oh, A. L. Kim, S. Y. Kim, J.-S. Shin, and D. Kim, Adv. Opt. Mater. 2, 48 (2014).
[Crossref]

Kim, D.

W. Lee, Y. Kinosita, Y. Oh, N. Mikami, H. Yang, M. Miyata, T. Nishizaka, and D. Kim, ACS Nano 9, 10896 (2015).
[Crossref]

J. Choi, K. Kim, Y. Oh, A. L. Kim, S. Y. Kim, J.-S. Shin, and D. Kim, Adv. Opt. Mater. 2, 48 (2014).
[Crossref]

K. Kim, J. Yajima, Y. Oh, W. Lee, S. Oowada, T. Nishizaka, and D. Kim, Small 8, 892 (2012).
[Crossref]

K. Kim, Y. Oh, W. Lee, and D. Kim, Opt. Lett. 35, 3501 (2010).
[Crossref]

D. J. Kim and D. Kim, J. Opt. Soc. Am. B 27, 1252 (2010).
[Crossref]

T. Son, J. Seo, I.-H. Choi, and D. Kim, “Label-free quantification of cell-to-substrate separation by surface plasmon resonance microscopy,” Opt. Commun., submitted for publication.
[Crossref]

Kim, D. J.

Kim, K.

J. Choi, K. Kim, Y. Oh, A. L. Kim, S. Y. Kim, J.-S. Shin, and D. Kim, Adv. Opt. Mater. 2, 48 (2014).
[Crossref]

K. Kim, J. Yajima, Y. Oh, W. Lee, S. Oowada, T. Nishizaka, and D. Kim, Small 8, 892 (2012).
[Crossref]

K. Kim, Y. Oh, W. Lee, and D. Kim, Opt. Lett. 35, 3501 (2010).
[Crossref]

Kim, S. Y.

J. Choi, K. Kim, Y. Oh, A. L. Kim, S. Y. Kim, J.-S. Shin, and D. Kim, Adv. Opt. Mater. 2, 48 (2014).
[Crossref]

Kim, Y. M.

J. S. Yuk, J. W. Jung, Y. M. Kim, and K. S. Ha, Sens. Actuators B 129, 113 (2008).
[Crossref]

Kinosita, Y.

W. Lee, Y. Kinosita, Y. Oh, N. Mikami, H. Yang, M. Miyata, T. Nishizaka, and D. Kim, ACS Nano 9, 10896 (2015).
[Crossref]

Knobloch, H.

H. Knobloch, G. von Szada-Borryszkowski, S. Woigk, A. Helms, and L. Brehmer, Appl. Phys. Lett. 69, 2336 (1996).
[Crossref]

Knoll, W.

D. Piscevic, W. Knoll, and M. J. Tarlov, Supramol. Sci. 2, 99 (1995).
[Crossref]

W. Hickel, D. Kamp, and W. Knoll, Nature 339, 186 (1989).
[Crossref]

B. Rothenhäusler and W. Knoll, Nature 332, 615 (1988).
[Crossref]

Kooyman, R. P.

C. E. Berger, R. P. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
[Crossref]

Kooyman, R. P. H.

R. P. H. Kooyman and U. J. Krull, Langmuir 7, 1506 (1991).
[Crossref]

Kotsev, S.

S. Kotsev, C. Dushkin, I. Ilev, and K. Nagayama, Colloid Polym. Sci. 281, 343 (2003).
[Crossref]

Krenn, J. R.

B. Lamprecht, J. R. Krenn, G. Schider, H. Ditlbacher, M. Salerno, N. Felidj, A. Leitner, F. R. Aussenegg, and J. C. Weeber, Appl. Phys. Lett. 79, 51 (2001).
[Crossref]

Krischer, K.

G. Flatgen, K. Krischer, B. Pettinger, and K. Doblhofer, Science 269, 668 (1995).
[Crossref]

Krull, U. J.

R. P. H. Kooyman and U. J. Krull, Langmuir 7, 1506 (1991).
[Crossref]

Lamprecht, B.

B. Lamprecht, J. R. Krenn, G. Schider, H. Ditlbacher, M. Salerno, N. Felidj, A. Leitner, F. R. Aussenegg, and J. C. Weeber, Appl. Phys. Lett. 79, 51 (2001).
[Crossref]

Laplatine, L.

Le Ru, E. C.

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B. Lamprecht, J. R. Krenn, G. Schider, H. Ditlbacher, M. Salerno, N. Felidj, A. Leitner, F. R. Aussenegg, and J. C. Weeber, Appl. Phys. Lett. 79, 51 (2001).
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T. Son, J. Seo, I.-H. Choi, and D. Kim, “Label-free quantification of cell-to-substrate separation by surface plasmon resonance microscopy,” Opt. Commun., submitted for publication.
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H. Yu, X. Shan, S. Wang, and N. Tao, Anal. Chem. 89, 2704 (2017).
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W. Wang, Y. Yang, S. Wang, V. J. Nagaraj, Q. Liu, J. Wu, and N. Tao, Nat. Chem. 4, 846 (2012).
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B. Huang, F. Yu, and R. N. Zare, Anal. Chem. 79, 2979 (2007).
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H. Yu, X. Shan, S. Wang, and N. Tao, Anal. Chem. 89, 2704 (2017).
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J. S. Yuk, J. W. Jung, Y. M. Kim, and K. S. Ha, Sens. Actuators B 129, 113 (2008).
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B. Huang, F. Yu, and R. N. Zare, Anal. Chem. 79, 2979 (2007).
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I. I. Smolyaninov, J. Elliott, G. Wurtz, A. V. Zayats, and C. C. Davis, Appl. Phys. B 84, 253 (2006).
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T. Zhang, H. Morgan, A. S. G. Curtis, and M. Riehle, J. Opt. A 3, 333 (2001).
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ACS Nano (2)

W. Lee, Y. Kinosita, Y. Oh, N. Mikami, H. Yang, M. Miyata, T. Nishizaka, and D. Kim, ACS Nano 9, 10896 (2015).
[Crossref]

K. Toma, H. Kano, and A. Offenhäusser, ACS Nano 8, 12612 (2014).
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Adv. Opt. Mater. (1)

J. Choi, K. Kim, Y. Oh, A. L. Kim, S. Y. Kim, J.-S. Shin, and D. Kim, Adv. Opt. Mater. 2, 48 (2014).
[Crossref]

Anal. Biochem. (1)

H. Shinohara, Y. Sakai, and T. A. Mir, Anal. Biochem. 441, 185 (2013).
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Anal. Chem. (2)

B. Huang, F. Yu, and R. N. Zare, Anal. Chem. 79, 2979 (2007).
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H. Yu, X. Shan, S. Wang, and N. Tao, Anal. Chem. 89, 2704 (2017).
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Appl. Opt. (1)

Appl. Phys. B (1)

I. I. Smolyaninov, J. Elliott, G. Wurtz, A. V. Zayats, and C. C. Davis, Appl. Phys. B 84, 253 (2006).
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Appl. Phys. Lett. (2)

B. Lamprecht, J. R. Krenn, G. Schider, H. Ditlbacher, M. Salerno, N. Felidj, A. Leitner, F. R. Aussenegg, and J. C. Weeber, Appl. Phys. Lett. 79, 51 (2001).
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Biomed. Opt. Express (2)

Biophys. J. (1)

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
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Biosens. Bioelectron. (1)

Y. Yanase, T. Hiragun, S. Kaneko, H. J. Gould, M. W. Greaves, and M. Hide, Biosens. Bioelectron. 26, 674 (2010).
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BMC Cell Biol. (1)

A. W. Peterson, M. Halter, A. Tona, K. Bhadriraju, and A. L. Plant, BMC Cell Biol. 10, 16 (2009).
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Colloid Polym. Sci. (1)

S. Kotsev, C. Dushkin, I. Ilev, and K. Nagayama, Colloid Polym. Sci. 281, 343 (2003).
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Colloids Surf. B (1)

C. F. Soon, S. A. Khaghani, M. Youseffi, N. Nayan, H. Saim, S. Britland, and M. C. T. Denyer, Colloids Surf. B 110, 156 (2013).
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J. Opt. A (1)

T. Zhang, H. Morgan, A. S. G. Curtis, and M. Riehle, J. Opt. A 3, 333 (2001).
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J. Opt. Soc. Am. B (1)

J. Phys. Chem. A (1)

S. A. Meyer, B. Auguié, E. C. Le Ru, and P. G. Etchegoin, J. Phys. Chem. A 116, 1000 (2012).
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Langmuir (2)

R. P. H. Kooyman and U. J. Krull, Langmuir 7, 1506 (1991).
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A. T. A. Jenkins, T. Neumann, and A. Offenhäusser, Langmuir 17, 265 (2001).
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W. Wang, Y. Yang, S. Wang, V. J. Nagaraj, Q. Liu, J. Wu, and N. Tao, Nat. Chem. 4, 846 (2012).
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Nature (2)

B. Rothenhäusler and W. Knoll, Nature 332, 615 (1988).
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W. Hickel, D. Kamp, and W. Knoll, Nature 339, 186 (1989).
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Opt. Express (4)

Opt. Lett. (3)

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C. E. Berger, R. P. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
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Science (2)

G. Flatgen, K. Krischer, B. Pettinger, and K. Doblhofer, Science 269, 668 (1995).
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X. Shan, U. Patel, S. Wang, R. Iglesias, and N. Tao, Science 327, 1363 (2010).
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Sens. Actuators (1)

B. Liedberg, C. Nylander, and I. Lunström, Sens. Actuators 4, 299 (1983).
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Sens. Actuators B (2)

J. S. Yuk, J. W. Jung, Y. M. Kim, and K. S. Ha, Sens. Actuators B 129, 113 (2008).
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R. Thariani and P. Yager, Sens. Actuators B 130, 765 (2008).
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Small (1)

K. Kim, J. Yajima, Y. Oh, W. Lee, S. Oowada, T. Nishizaka, and D. Kim, Small 8, 892 (2012).
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Supramol. Sci. (1)

D. Piscevic, W. Knoll, and M. J. Tarlov, Supramol. Sci. 2, 99 (1995).
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Other (1)

T. Son, J. Seo, I.-H. Choi, and D. Kim, “Label-free quantification of cell-to-substrate separation by surface plasmon resonance microscopy,” Opt. Commun., submitted for publication.
[Crossref]

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Figures (4)

Fig. 1.
Fig. 1. (a) Schematic of the optical setup of ssSPM (FL, focusing lens with f = 200    mm ; M1 and M2, mirrors; NDF, neutral density filter; SF, spatial filter; P, polarizer; and TL, tube lens). (b) Conceptual illustration of switching in the ssSPM. Ch. 1 and 2 represent laser illumination at a nanowire for momentum sampling in two opposite directions at an identical angle of incidence.
Fig. 2.
Fig. 2. (a) Images of conventional SPM and ssSPM of nanowires (550 nm width) in comparison with BM. Conventional single-channel SPM: (a) Ch. 1 and (b) Ch. 2. The red arrows indicate the direction of light incidence. (c) ssSPM and (d) bright-field image. (e) Normalized intensity along the horizontal ( y ) direction in (a)–(d). The intensity was averaged vertically ( x ) over the dashed rectangle. os and ss represent, respectively, the opposite and the same sides with respect to the light incidence.
Fig. 3.
Fig. 3. (a) Images of periodic wires of 1.1 μm width in conventional single-channel SPM: (a) Ch. 1 and (b) Ch. 2 and of (c) ssSPM and (d) BM. Scale bar: 10 μm. The wire orientation is parallel to the direction of light incidence. (e) Normalized intensity and (f) histograms of propagation length L 80 / 20 . The numbers represent the center and the standard deviation of the distribution of L 80 / 20 . Images of conventional SPM and ssSPM of reference periodic wires ( w = 0.15    μm , 0.55 μm, 1.1 μm, and 7.8 μm from top to bottom rows) compared with BM in the perpendicular orientation. Conventional single-channel SPM: (g) Ch. 1 and (h) Ch. 2. (i) ssSPM and (j) BM image. Red arrows indicate the direction of light incidence.
Fig. 4.
Fig. 4. Images of single nanoparticle point diffraction and A549 cells: (a) Ch. 1 and (b) Ch. 2 by conventional SPM. Red arrows of (a) and (b) indicate the direction of light incidence with respect to the text. (c) ssSPM and (d) BM. α-row is scattering images of a single resist polymer nanoparticle (diam. ϕ = 250    nm ). Black arrow in (d) shows a single nanoparticle under BM. (β)–(ϵ) represents different sites of the cell culture that was imaged. δ inset: magnified cell membrane.

Tables (1)

Tables Icon

Table 1. Enhancement Factor ( E F ) of ssSPM ( n : Number of Sample Measurements)

Metrics