Abstract

We propose a novel OCT-based method for visualizing microvasculature in three-dimension using reference-free processing of individual complex valued B-scans with highly overlapped A-scans. In the lateral direction of such a B-scan, the amplitude and phase of speckles corresponding to vessel regions exhibit faster variability and, thus, can be detected without comparison with other B-scans recorded in the same plane. This method combines elements of several existing OCT angiographic approaches and exhibits: (1) enhanced robustness with respect to bulk tissue motion with frequencies up to tens of Hz, (2) resolution of microcirculation images equal to that of structural images, and (3) possibility of quantifying the vessels in terms of their decorrelation rates.

© 2015 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Optimized speckle variance OCT imaging of microvasculature

Adrian Mariampillai, Michael K. K. Leung, Mark Jarvi, Beau A. Standish, Kenneth Lee, Brian C. Wilson, Alex Vitkin, and Victor X. D. Yang
Opt. Lett. 35(8) 1257-1259 (2010)

In vivo label-free lymphangiography of cutaneous lymphatic vessels in human burn scars using optical coherence tomography

Peijun Gong, Shaghayegh Es’haghian, Karl-Anton Harms, Alexandra Murray, Suzanne Rea, Fiona M. Wood, David D. Sampson, and Robert A. McLaughlin
Biomed. Opt. Express 7(12) 4886-4898 (2016)

Split-spectrum amplitude-decorrelation angiography with optical coherence tomography

Yali Jia, Ou Tan, Jason Tokayer, Benjamin Potsaid, Yimin Wang, Jonathan J. Liu, Martin F. Kraus, Hrebesh Subhash, James G. Fujimoto, Joachim Hornegger, and David Huang
Opt. Express 20(4) 4710-4725 (2012)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Supplementary Material (2)

» Media 1: AVI (8230 KB)     
» Media 2: AVI (357 KB)     

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (2)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (1)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription