Abstract
We report a novel Fourier-transform-based implementation of coherent anti-Stokes Raman scattering (CARS) microscopy. The method employs a single femtosecond laser source and a Michelson interferometer to create two pulse replicas that are fed into a scanning multiphoton microscope. By varying the time delay between the pulses, we time-resolve the CARS signal, permitting easy removal of the nonresonant background while providing high resolution, spectrally resolved images of CARS modes over the laser bandwidth . We demonstrate the method by imaging polystyrene beads in solvent.
© 2006 Optical Society of America
Full Article | PDF ArticleMore Like This
Meng Cui, Joshua Skodack, and Jennifer P. Ogilvie
Appl. Opt. 47(31) 5790-5798 (2008)
Meng Cui, Manuel Joffre, Joshua Skodack, and Jennifer P. Ogilvie
Opt. Express 14(18) 8448-8458 (2006)
Eric O. Potma, Conor L. Evans, and X. Sunney Xie
Opt. Lett. 31(2) 241-243 (2006)