Abstract

Otitis Media (OM) is related to a group of inflammatory diseases of the middle ear (ME) commonly encountered, worldwide. A method based on a simple device, which can be used by medical staff and non-experts to detect OM is presented. The method is based on detection of tympanic membrane (TM) vibrations. A laser beam is pointed on an infra-sonic stimulated TM with fast camera capturing the back scattered secondary speckle patterns. A camera enables inspection of the frequency and amplitude of the changes in TM characteristics obtained by analysis of the spatial-temporal statistics of the speckle patterns. The results may provide information that express ME effusion.

© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

Full Article  |  PDF Article
OSA Recommended Articles
Light field otoscope design for 3D in vivo imaging of the middle ear

Noah Bedard, Timothy Shope, Alejandro Hoberman, Mary Ann Haralam, Nader Shaikh, Jelena Kovačević, Nikhil Balram, and Ivana Tošić
Biomed. Opt. Express 8(1) 260-272 (2017)

Anti-confocal assessment of middle ear inflammation

David S. Jung, John A. Crowe, John P. Birchall, Michael G. Somekh, and Chung W. See
Biomed. Opt. Express 8(1) 230-242 (2017)

Anti-confocal versus confocal assessment of the middle ear simulated by Monte Carlo methods

David S. Jung, John A. Crowe, John P. Birchall, Michael G. Somekh, and Chung W. See
Biomed. Opt. Express 6(10) 3820-3825 (2015)

References

  • View by:
  • |
  • |
  • |

  1. M. Tos, “Epidemiology and natural history of secretory otitis,” Am. J. Otol. 5(6), 459–462 (1984).
    [PubMed]
  2. Q. Zhang, J. Wei, and M. Xu “Prevalence of otitis media with effusion among children in Xi'an, China: a randomized survey in China's mainland,”, 120, 617–621 (2011).
  3. S. Berman, “Otitis Media in Children,” N. Engl. J. Med. 332(23), 1560–1565 (1995).
    [Crossref] [PubMed]
  4. M. Iversen, L. Birch, G. R. Lundqvist, and O. Elbrønd, “Middle ear effusion in children and the indoor environment: an epidemiological study,” Arch. Environ. Health 40(2), 74–79 (1985).
    [Crossref] [PubMed]
  5. M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
    [Crossref] [PubMed]
  6. J. Lous and M. Fiellau-Nikolajsen, “Epidemiology and middle ear effusion and tubal dysfunction. a one-year prospective study comprising monthly tympanometry in 387 non-selected 7-year-old children,” Int. J. Pediatr. Otorhinolaryngol. 3(4), 303–317 (1981).
    [Crossref] [PubMed]
  7. M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
    [Crossref] [PubMed]
  8. D. W. Teele, J. O. Klein, and B. A. Rosner, “Otitis media with effusion during the first three years of life and development of speech and language,” Pediatrics 74(2), 282–287 (1984).
    [PubMed]
  9. H. Atkinson, S. Wallis, and A. P. Coatesworth, “Otitis media with effusion,” Postgrad. Med. 127(4), 381–385 (2015).
    [Crossref] [PubMed]
  10. T. Muderris, A. Yazıcı, S. Bercin, G. Yalçıner, E. Sevil, and M. Kırıs, “Consumer acoustic reflectometry: accuracy in diagnosis of otitis media with effusion in children,” Int. J. Pediatr. Otorhinolaryngol. 77(10), 1771–1774 (2013).
    [Crossref] [PubMed]
  11. J. E. MacClements, M. Parchman, and C. Passmore, “Otitis media in children: use of diagnostic tools by family practice residents,” Fam. Med. 34(8), 598–603 (2002).
    [PubMed]
  12. G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
    [Crossref] [PubMed]
  13. I. Williamson, “Otitis media with effusion,” Clin. Evid. 7(7), 469–476 (2002).
    [PubMed]
  14. M. E. Pichichero, “Acute otitis media: Part I. Improving diagnostic accuracy,” Am. Fam. Physician 61(7), 2051–2056 (2000).
    [PubMed]
  15. G. S. Takata, L. S. Chan, T. Morphew, R. Mangione-Smith, S. C. Morton, and P. Shekelle, “Evidence Assessment of the Accuracy of Methods of Diagnosing Middle Ear Effusion in Children With Otitis Media With Effusion,” Pediatrics 112(6), 1379–1387 (2003).
    [Crossref] [PubMed]
  16. H. Lindén, H. Teppo, and M. Revonta, “Spectral gradient acoustic reflectometry in the diagnosis of middle-ear fluid in children,” Eur. Arch. Otorhinolaryngol. 264(5), 477–481 (2007).
    [Crossref] [PubMed]
  17. M. K. Laine, P. A. Tähtinen, K. K. Helenius, R. Luoto, and A. Ruohola, “Acoustic Reflectometry in Discrimination of Otoscopic Diagnoses in Young Ambulatory Children,” Pediatr. Infect. Dis. J. 31(10), 1007–1011 (2012).
    [PubMed]
  18. R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
    [Crossref] [PubMed]
  19. J. W. Goodman, “Some fundamental properties of speckle,” J. Opt. Soc. Am. 66(11), 1145–1150 (1976).
    [Crossref]
  20. Z. Zalevsky, Y. Beiderman, I. Margalit, S. Gingold, M. Teicher, V. Mico, and J. Garcia, “Simultaneous remote extraction of multiple speech sources and heart beats from secondary speckles pattern,” Opt. Express 17(24), 21566–21580 (2009).
    [Crossref] [PubMed]
  21. N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
    [Crossref]
  22. N. Ozana, N. Arbel, Y. Beiderman, V. Mico, M. Sanz, J. Garcia, A. Anand, B. Javidi, Y. Epstein, and Z. Zalevsky, “Improved noncontact optical sensor for detection of glucose concentration and indication of dehydration level,” Biomed. Opt. Express 5(6), 1926–1940 (2014).
    [Crossref] [PubMed]
  23. Y. Beiderman, I. Horovitz, N. Burshtein, M. Teicher, J. Garcia, V. Mico, and Z. Zalevsky, “Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern,” J. Biomed. Opt. 15(6), 061707 (2010).
    [Crossref] [PubMed]
  24. A. Shenhav, Z. Brodie, Y. Beiderman, J. Garcia, V. Mico, and Z. Zalevsky, “Optical sensor for remote estimation of alcohol concentration in blood stream,” Opt. Commun. 289, 149–157 (2013).
    [Crossref]
  25. Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).
  26. N. Ozana, S. Buchsbaum, Y. Bishitz, Y. Beiderman, Z. Schmilovitch, A. Schwarz, A. Shemer, J. Keshet, and Z. Zalevsky, “Optical remote sensor for peanut kernel abortion classification,” Appl. Opt. 55(15), 4005–4010 (2016).
    [Crossref] [PubMed]
  27. N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
    [Crossref] [PubMed]
  28. N. Ozana, Y. Bishitz, Y. Beiderman, J. Garcia, and Z. Zalevsky, “Remote optical configuration of pigmented lesion detection and diagnosis of bone fractures,” Proc. SPIE 9689, 968916 (2016).
  29. S. Van der Jeught, J. J. J. Dirckx, J. R. M. Aerts, A. Bradu, A. G. Podoleanu, and J. A. N. Buytaert, “Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography,” J. Assoc. Res. Otolaryngol. 14(4), 483–494 (2013).
    [Crossref] [PubMed]
  30. P. Razavi, M. E. Ravicz, I. Dobrev, J. T. Cheng, C. Furlong, and J. J. Rosowski, “Response of the human tympanic membrane to transient acoustic and mechanical stimuli: Preliminary results,” Hear. Res. 340, 15–24 (2016).
    [Crossref] [PubMed]
  31. R. Z. Gan, C. Dai, and M. W. Wood, “Laser interferometry measurements of middle ear fluid and pressure effects on sound transmission,” J. Acoust. Soc. Am. 120(6), 3799–3810 (2006).
    [Crossref] [PubMed]

2017 (1)

G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
[Crossref] [PubMed]

2016 (5)

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

N. Ozana, S. Buchsbaum, Y. Bishitz, Y. Beiderman, Z. Schmilovitch, A. Schwarz, A. Shemer, J. Keshet, and Z. Zalevsky, “Optical remote sensor for peanut kernel abortion classification,” Appl. Opt. 55(15), 4005–4010 (2016).
[Crossref] [PubMed]

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

N. Ozana, Y. Bishitz, Y. Beiderman, J. Garcia, and Z. Zalevsky, “Remote optical configuration of pigmented lesion detection and diagnosis of bone fractures,” Proc. SPIE 9689, 968916 (2016).

P. Razavi, M. E. Ravicz, I. Dobrev, J. T. Cheng, C. Furlong, and J. J. Rosowski, “Response of the human tympanic membrane to transient acoustic and mechanical stimuli: Preliminary results,” Hear. Res. 340, 15–24 (2016).
[Crossref] [PubMed]

2015 (2)

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

H. Atkinson, S. Wallis, and A. P. Coatesworth, “Otitis media with effusion,” Postgrad. Med. 127(4), 381–385 (2015).
[Crossref] [PubMed]

2014 (1)

2013 (3)

A. Shenhav, Z. Brodie, Y. Beiderman, J. Garcia, V. Mico, and Z. Zalevsky, “Optical sensor for remote estimation of alcohol concentration in blood stream,” Opt. Commun. 289, 149–157 (2013).
[Crossref]

S. Van der Jeught, J. J. J. Dirckx, J. R. M. Aerts, A. Bradu, A. G. Podoleanu, and J. A. N. Buytaert, “Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography,” J. Assoc. Res. Otolaryngol. 14(4), 483–494 (2013).
[Crossref] [PubMed]

T. Muderris, A. Yazıcı, S. Bercin, G. Yalçıner, E. Sevil, and M. Kırıs, “Consumer acoustic reflectometry: accuracy in diagnosis of otitis media with effusion in children,” Int. J. Pediatr. Otorhinolaryngol. 77(10), 1771–1774 (2013).
[Crossref] [PubMed]

2012 (2)

M. K. Laine, P. A. Tähtinen, K. K. Helenius, R. Luoto, and A. Ruohola, “Acoustic Reflectometry in Discrimination of Otoscopic Diagnoses in Young Ambulatory Children,” Pediatr. Infect. Dis. J. 31(10), 1007–1011 (2012).
[PubMed]

Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).

2010 (1)

Y. Beiderman, I. Horovitz, N. Burshtein, M. Teicher, J. Garcia, V. Mico, and Z. Zalevsky, “Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern,” J. Biomed. Opt. 15(6), 061707 (2010).
[Crossref] [PubMed]

2009 (1)

2007 (1)

H. Lindén, H. Teppo, and M. Revonta, “Spectral gradient acoustic reflectometry in the diagnosis of middle-ear fluid in children,” Eur. Arch. Otorhinolaryngol. 264(5), 477–481 (2007).
[Crossref] [PubMed]

2006 (1)

R. Z. Gan, C. Dai, and M. W. Wood, “Laser interferometry measurements of middle ear fluid and pressure effects on sound transmission,” J. Acoust. Soc. Am. 120(6), 3799–3810 (2006).
[Crossref] [PubMed]

2003 (1)

G. S. Takata, L. S. Chan, T. Morphew, R. Mangione-Smith, S. C. Morton, and P. Shekelle, “Evidence Assessment of the Accuracy of Methods of Diagnosing Middle Ear Effusion in Children With Otitis Media With Effusion,” Pediatrics 112(6), 1379–1387 (2003).
[Crossref] [PubMed]

2002 (2)

I. Williamson, “Otitis media with effusion,” Clin. Evid. 7(7), 469–476 (2002).
[PubMed]

J. E. MacClements, M. Parchman, and C. Passmore, “Otitis media in children: use of diagnostic tools by family practice residents,” Fam. Med. 34(8), 598–603 (2002).
[PubMed]

2000 (1)

M. E. Pichichero, “Acute otitis media: Part I. Improving diagnostic accuracy,” Am. Fam. Physician 61(7), 2051–2056 (2000).
[PubMed]

1995 (1)

S. Berman, “Otitis Media in Children,” N. Engl. J. Med. 332(23), 1560–1565 (1995).
[Crossref] [PubMed]

1985 (3)

M. Iversen, L. Birch, G. R. Lundqvist, and O. Elbrønd, “Middle ear effusion in children and the indoor environment: an epidemiological study,” Arch. Environ. Health 40(2), 74–79 (1985).
[Crossref] [PubMed]

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

1984 (2)

D. W. Teele, J. O. Klein, and B. A. Rosner, “Otitis media with effusion during the first three years of life and development of speech and language,” Pediatrics 74(2), 282–287 (1984).
[PubMed]

M. Tos, “Epidemiology and natural history of secretory otitis,” Am. J. Otol. 5(6), 459–462 (1984).
[PubMed]

1981 (1)

J. Lous and M. Fiellau-Nikolajsen, “Epidemiology and middle ear effusion and tubal dysfunction. a one-year prospective study comprising monthly tympanometry in 387 non-selected 7-year-old children,” Int. J. Pediatr. Otorhinolaryngol. 3(4), 303–317 (1981).
[Crossref] [PubMed]

1976 (1)

Aerts, J. R. M.

S. Van der Jeught, J. J. J. Dirckx, J. R. M. Aerts, A. Bradu, A. G. Podoleanu, and J. A. N. Buytaert, “Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography,” J. Assoc. Res. Otolaryngol. 14(4), 483–494 (2013).
[Crossref] [PubMed]

Anand, A.

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

N. Ozana, N. Arbel, Y. Beiderman, V. Mico, M. Sanz, J. Garcia, A. Anand, B. Javidi, Y. Epstein, and Z. Zalevsky, “Improved noncontact optical sensor for detection of glucose concentration and indication of dehydration level,” Biomed. Opt. Express 5(6), 1926–1940 (2014).
[Crossref] [PubMed]

Arbel, N.

Atkinson, H.

H. Atkinson, S. Wallis, and A. P. Coatesworth, “Otitis media with effusion,” Postgrad. Med. 127(4), 381–385 (2015).
[Crossref] [PubMed]

Beiderman, Y.

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

N. Ozana, Y. Bishitz, Y. Beiderman, J. Garcia, and Z. Zalevsky, “Remote optical configuration of pigmented lesion detection and diagnosis of bone fractures,” Proc. SPIE 9689, 968916 (2016).

N. Ozana, S. Buchsbaum, Y. Bishitz, Y. Beiderman, Z. Schmilovitch, A. Schwarz, A. Shemer, J. Keshet, and Z. Zalevsky, “Optical remote sensor for peanut kernel abortion classification,” Appl. Opt. 55(15), 4005–4010 (2016).
[Crossref] [PubMed]

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

N. Ozana, N. Arbel, Y. Beiderman, V. Mico, M. Sanz, J. Garcia, A. Anand, B. Javidi, Y. Epstein, and Z. Zalevsky, “Improved noncontact optical sensor for detection of glucose concentration and indication of dehydration level,” Biomed. Opt. Express 5(6), 1926–1940 (2014).
[Crossref] [PubMed]

A. Shenhav, Z. Brodie, Y. Beiderman, J. Garcia, V. Mico, and Z. Zalevsky, “Optical sensor for remote estimation of alcohol concentration in blood stream,” Opt. Commun. 289, 149–157 (2013).
[Crossref]

Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).

Y. Beiderman, I. Horovitz, N. Burshtein, M. Teicher, J. Garcia, V. Mico, and Z. Zalevsky, “Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern,” J. Biomed. Opt. 15(6), 061707 (2010).
[Crossref] [PubMed]

Z. Zalevsky, Y. Beiderman, I. Margalit, S. Gingold, M. Teicher, V. Mico, and J. Garcia, “Simultaneous remote extraction of multiple speech sources and heart beats from secondary speckles pattern,” Opt. Express 17(24), 21566–21580 (2009).
[Crossref] [PubMed]

Belkin, M.

Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).

Bercin, S.

T. Muderris, A. Yazıcı, S. Bercin, G. Yalçıner, E. Sevil, and M. Kırıs, “Consumer acoustic reflectometry: accuracy in diagnosis of otitis media with effusion in children,” Int. J. Pediatr. Otorhinolaryngol. 77(10), 1771–1774 (2013).
[Crossref] [PubMed]

Berman, S.

S. Berman, “Otitis Media in Children,” N. Engl. J. Med. 332(23), 1560–1565 (1995).
[Crossref] [PubMed]

Birch, L.

M. Iversen, L. Birch, G. R. Lundqvist, and O. Elbrønd, “Middle ear effusion in children and the indoor environment: an epidemiological study,” Arch. Environ. Health 40(2), 74–79 (1985).
[Crossref] [PubMed]

Bishitz, Y.

N. Ozana, Y. Bishitz, Y. Beiderman, J. Garcia, and Z. Zalevsky, “Remote optical configuration of pigmented lesion detection and diagnosis of bone fractures,” Proc. SPIE 9689, 968916 (2016).

N. Ozana, S. Buchsbaum, Y. Bishitz, Y. Beiderman, Z. Schmilovitch, A. Schwarz, A. Shemer, J. Keshet, and Z. Zalevsky, “Optical remote sensor for peanut kernel abortion classification,” Appl. Opt. 55(15), 4005–4010 (2016).
[Crossref] [PubMed]

Bluestone, C. D.

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

Boppart, S. A.

G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
[Crossref] [PubMed]

Bradu, A.

S. Van der Jeught, J. J. J. Dirckx, J. R. M. Aerts, A. Bradu, A. G. Podoleanu, and J. A. N. Buytaert, “Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography,” J. Assoc. Res. Otolaryngol. 14(4), 483–494 (2013).
[Crossref] [PubMed]

Brodie, Z.

A. Shenhav, Z. Brodie, Y. Beiderman, J. Garcia, V. Mico, and Z. Zalevsky, “Optical sensor for remote estimation of alcohol concentration in blood stream,” Opt. Commun. 289, 149–157 (2013).
[Crossref]

Brostoff, L. M.

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

Buchsbaum, S.

Burshtein, N.

Y. Beiderman, I. Horovitz, N. Burshtein, M. Teicher, J. Garcia, V. Mico, and Z. Zalevsky, “Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern,” J. Biomed. Opt. 15(6), 061707 (2010).
[Crossref] [PubMed]

Buytaert, J. A. N.

S. Van der Jeught, J. J. J. Dirckx, J. R. M. Aerts, A. Bradu, A. G. Podoleanu, and J. A. N. Buytaert, “Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography,” J. Assoc. Res. Otolaryngol. 14(4), 483–494 (2013).
[Crossref] [PubMed]

Campino, G. A.

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

Cantekin, E. I.

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

Casselbrant, M. L.

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

Chan, L. S.

G. S. Takata, L. S. Chan, T. Morphew, R. Mangione-Smith, S. C. Morton, and P. Shekelle, “Evidence Assessment of the Accuracy of Methods of Diagnosing Middle Ear Effusion in Children With Otitis Media With Effusion,” Pediatrics 112(6), 1379–1387 (2003).
[Crossref] [PubMed]

Cheng, J. T.

P. Razavi, M. E. Ravicz, I. Dobrev, J. T. Cheng, C. Furlong, and J. J. Rosowski, “Response of the human tympanic membrane to transient acoustic and mechanical stimuli: Preliminary results,” Hear. Res. 340, 15–24 (2016).
[Crossref] [PubMed]

Coatesworth, A. P.

H. Atkinson, S. Wallis, and A. P. Coatesworth, “Otitis media with effusion,” Postgrad. Med. 127(4), 381–385 (2015).
[Crossref] [PubMed]

Coggins, R.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Corrigan, M. D.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Dai, C.

R. Z. Gan, C. Dai, and M. W. Wood, “Laser interferometry measurements of middle ear fluid and pressure effects on sound transmission,” J. Acoust. Soc. Am. 120(6), 3799–3810 (2006).
[Crossref] [PubMed]

Dirckx, J. J. J.

S. Van der Jeught, J. J. J. Dirckx, J. R. M. Aerts, A. Bradu, A. G. Podoleanu, and J. A. N. Buytaert, “Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography,” J. Assoc. Res. Otolaryngol. 14(4), 483–494 (2013).
[Crossref] [PubMed]

Dobrev, I.

P. Razavi, M. E. Ravicz, I. Dobrev, J. T. Cheng, C. Furlong, and J. J. Rosowski, “Response of the human tympanic membrane to transient acoustic and mechanical stimuli: Preliminary results,” Hear. Res. 340, 15–24 (2016).
[Crossref] [PubMed]

Doyle, W. J.

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

Elbrønd, O.

M. Iversen, L. Birch, G. R. Lundqvist, and O. Elbrønd, “Middle ear effusion in children and the indoor environment: an epidemiological study,” Arch. Environ. Health 40(2), 74–79 (1985).
[Crossref] [PubMed]

Epstein, Y.

Fiellau-Nikolajsen, M.

J. Lous and M. Fiellau-Nikolajsen, “Epidemiology and middle ear effusion and tubal dysfunction. a one-year prospective study comprising monthly tympanometry in 387 non-selected 7-year-old children,” Int. J. Pediatr. Otorhinolaryngol. 3(4), 303–317 (1981).
[Crossref] [PubMed]

Flaherty, M. R.

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

Fria, T. J.

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

Furlong, C.

P. Razavi, M. E. Ravicz, I. Dobrev, J. T. Cheng, C. Furlong, and J. J. Rosowski, “Response of the human tympanic membrane to transient acoustic and mechanical stimuli: Preliminary results,” Hear. Res. 340, 15–24 (2016).
[Crossref] [PubMed]

Gagnon, L.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Gan, R. Z.

R. Z. Gan, C. Dai, and M. W. Wood, “Laser interferometry measurements of middle ear fluid and pressure effects on sound transmission,” J. Acoust. Soc. Am. 120(6), 3799–3810 (2006).
[Crossref] [PubMed]

Garcia, J.

N. Ozana, Y. Bishitz, Y. Beiderman, J. Garcia, and Z. Zalevsky, “Remote optical configuration of pigmented lesion detection and diagnosis of bone fractures,” Proc. SPIE 9689, 968916 (2016).

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

N. Ozana, N. Arbel, Y. Beiderman, V. Mico, M. Sanz, J. Garcia, A. Anand, B. Javidi, Y. Epstein, and Z. Zalevsky, “Improved noncontact optical sensor for detection of glucose concentration and indication of dehydration level,” Biomed. Opt. Express 5(6), 1926–1940 (2014).
[Crossref] [PubMed]

A. Shenhav, Z. Brodie, Y. Beiderman, J. Garcia, V. Mico, and Z. Zalevsky, “Optical sensor for remote estimation of alcohol concentration in blood stream,” Opt. Commun. 289, 149–157 (2013).
[Crossref]

Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).

Y. Beiderman, I. Horovitz, N. Burshtein, M. Teicher, J. Garcia, V. Mico, and Z. Zalevsky, “Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern,” J. Biomed. Opt. 15(6), 061707 (2010).
[Crossref] [PubMed]

Z. Zalevsky, Y. Beiderman, I. Margalit, S. Gingold, M. Teicher, V. Mico, and J. Garcia, “Simultaneous remote extraction of multiple speech sources and heart beats from secondary speckles pattern,” Opt. Express 17(24), 21566–21580 (2009).
[Crossref] [PubMed]

Gerasi, R.

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

Gingold, S.

Goodman, J. W.

Hackell, J. M.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Helenius, K. K.

M. K. Laine, P. A. Tähtinen, K. K. Helenius, R. Luoto, and A. Ruohola, “Acoustic Reflectometry in Discrimination of Otoscopic Diagnoses in Young Ambulatory Children,” Pediatr. Infect. Dis. J. 31(10), 1007–1011 (2012).
[PubMed]

Hoelting, D.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Horovitz, I.

Y. Beiderman, I. Horovitz, N. Burshtein, M. Teicher, J. Garcia, V. Mico, and Z. Zalevsky, “Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern,” J. Biomed. Opt. 15(6), 061707 (2010).
[Crossref] [PubMed]

Hunter, L. L.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Iversen, M.

M. Iversen, L. Birch, G. R. Lundqvist, and O. Elbrønd, “Middle ear effusion in children and the indoor environment: an epidemiological study,” Arch. Environ. Health 40(2), 74–79 (1985).
[Crossref] [PubMed]

Javidi, B.

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

N. Ozana, N. Arbel, Y. Beiderman, V. Mico, M. Sanz, J. Garcia, A. Anand, B. Javidi, Y. Epstein, and Z. Zalevsky, “Improved noncontact optical sensor for detection of glucose concentration and indication of dehydration level,” Biomed. Opt. Express 5(6), 1926–1940 (2014).
[Crossref] [PubMed]

Keshet, J.

Kiris, M.

T. Muderris, A. Yazıcı, S. Bercin, G. Yalçıner, E. Sevil, and M. Kırıs, “Consumer acoustic reflectometry: accuracy in diagnosis of otitis media with effusion in children,” Int. J. Pediatr. Otorhinolaryngol. 77(10), 1771–1774 (2013).
[Crossref] [PubMed]

Klein, J. O.

D. W. Teele, J. O. Klein, and B. A. Rosner, “Otitis media with effusion during the first three years of life and development of speech and language,” Pediatrics 74(2), 282–287 (1984).
[PubMed]

Kummer, A. W.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Kunin, M.

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

Laine, M. K.

M. K. Laine, P. A. Tähtinen, K. K. Helenius, R. Luoto, and A. Ruohola, “Acoustic Reflectometry in Discrimination of Otoscopic Diagnoses in Young Ambulatory Children,” Pediatr. Infect. Dis. J. 31(10), 1007–1011 (2012).
[PubMed]

Lindén, H.

H. Lindén, H. Teppo, and M. Revonta, “Spectral gradient acoustic reflectometry in the diagnosis of middle-ear fluid in children,” Eur. Arch. Otorhinolaryngol. 264(5), 477–481 (2007).
[Crossref] [PubMed]

Lous, J.

J. Lous and M. Fiellau-Nikolajsen, “Epidemiology and middle ear effusion and tubal dysfunction. a one-year prospective study comprising monthly tympanometry in 387 non-selected 7-year-old children,” Int. J. Pediatr. Otorhinolaryngol. 3(4), 303–317 (1981).
[Crossref] [PubMed]

Lundqvist, G. R.

M. Iversen, L. Birch, G. R. Lundqvist, and O. Elbrønd, “Middle ear effusion in children and the indoor environment: an epidemiological study,” Arch. Environ. Health 40(2), 74–79 (1985).
[Crossref] [PubMed]

Luoto, R.

M. K. Laine, P. A. Tähtinen, K. K. Helenius, R. Luoto, and A. Ruohola, “Acoustic Reflectometry in Discrimination of Otoscopic Diagnoses in Young Ambulatory Children,” Pediatr. Infect. Dis. J. 31(10), 1007–1011 (2012).
[PubMed]

MacClements, J. E.

J. E. MacClements, M. Parchman, and C. Passmore, “Otitis media in children: use of diagnostic tools by family practice residents,” Fam. Med. 34(8), 598–603 (2002).
[PubMed]

Mangione-Smith, R.

G. S. Takata, L. S. Chan, T. Morphew, R. Mangione-Smith, S. C. Morton, and P. Shekelle, “Evidence Assessment of the Accuracy of Methods of Diagnosing Middle Ear Effusion in Children With Otitis Media With Effusion,” Pediatrics 112(6), 1379–1387 (2003).
[Crossref] [PubMed]

Margalit, I.

Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).

Z. Zalevsky, Y. Beiderman, I. Margalit, S. Gingold, M. Teicher, V. Mico, and J. Garcia, “Simultaneous remote extraction of multiple speech sources and heart beats from secondary speckles pattern,” Opt. Express 17(24), 21566–21580 (2009).
[Crossref] [PubMed]

Margalith, I.

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

Mico, V.

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

N. Ozana, N. Arbel, Y. Beiderman, V. Mico, M. Sanz, J. Garcia, A. Anand, B. Javidi, Y. Epstein, and Z. Zalevsky, “Improved noncontact optical sensor for detection of glucose concentration and indication of dehydration level,” Biomed. Opt. Express 5(6), 1926–1940 (2014).
[Crossref] [PubMed]

A. Shenhav, Z. Brodie, Y. Beiderman, J. Garcia, V. Mico, and Z. Zalevsky, “Optical sensor for remote estimation of alcohol concentration in blood stream,” Opt. Commun. 289, 149–157 (2013).
[Crossref]

Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).

Y. Beiderman, I. Horovitz, N. Burshtein, M. Teicher, J. Garcia, V. Mico, and Z. Zalevsky, “Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern,” J. Biomed. Opt. 15(6), 061707 (2010).
[Crossref] [PubMed]

Z. Zalevsky, Y. Beiderman, I. Margalit, S. Gingold, M. Teicher, V. Mico, and J. Garcia, “Simultaneous remote extraction of multiple speech sources and heart beats from secondary speckles pattern,” Opt. Express 17(24), 21566–21580 (2009).
[Crossref] [PubMed]

Monroy, G. L.

G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
[Crossref] [PubMed]

Morphew, T.

G. S. Takata, L. S. Chan, T. Morphew, R. Mangione-Smith, S. C. Morton, and P. Shekelle, “Evidence Assessment of the Accuracy of Methods of Diagnosing Middle Ear Effusion in Children With Otitis Media With Effusion,” Pediatrics 112(6), 1379–1387 (2003).
[Crossref] [PubMed]

Morton, S. C.

G. S. Takata, L. S. Chan, T. Morphew, R. Mangione-Smith, S. C. Morton, and P. Shekelle, “Evidence Assessment of the Accuracy of Methods of Diagnosing Middle Ear Effusion in Children With Otitis Media With Effusion,” Pediatrics 112(6), 1379–1387 (2003).
[Crossref] [PubMed]

Muderris, T.

T. Muderris, A. Yazıcı, S. Bercin, G. Yalçıner, E. Sevil, and M. Kırıs, “Consumer acoustic reflectometry: accuracy in diagnosis of otitis media with effusion in children,” Int. J. Pediatr. Otorhinolaryngol. 77(10), 1771–1774 (2013).
[Crossref] [PubMed]

Nolan, R. M.

G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
[Crossref] [PubMed]

Novak, M. A.

G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
[Crossref] [PubMed]

Ozana, N.

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

N. Ozana, Y. Bishitz, Y. Beiderman, J. Garcia, and Z. Zalevsky, “Remote optical configuration of pigmented lesion detection and diagnosis of bone fractures,” Proc. SPIE 9689, 968916 (2016).

N. Ozana, S. Buchsbaum, Y. Bishitz, Y. Beiderman, Z. Schmilovitch, A. Schwarz, A. Shemer, J. Keshet, and Z. Zalevsky, “Optical remote sensor for peanut kernel abortion classification,” Appl. Opt. 55(15), 4005–4010 (2016).
[Crossref] [PubMed]

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

N. Ozana, N. Arbel, Y. Beiderman, V. Mico, M. Sanz, J. Garcia, A. Anand, B. Javidi, Y. Epstein, and Z. Zalevsky, “Improved noncontact optical sensor for detection of glucose concentration and indication of dehydration level,” Biomed. Opt. Express 5(6), 1926–1940 (2014).
[Crossref] [PubMed]

Pande, P.

G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
[Crossref] [PubMed]

Parchman, M.

J. E. MacClements, M. Parchman, and C. Passmore, “Otitis media in children: use of diagnostic tools by family practice residents,” Fam. Med. 34(8), 598–603 (2002).
[PubMed]

Passmore, C.

J. E. MacClements, M. Parchman, and C. Passmore, “Otitis media in children: use of diagnostic tools by family practice residents,” Fam. Med. 34(8), 598–603 (2002).
[PubMed]

Payne, S. C.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Pichichero, M. E.

M. E. Pichichero, “Acute otitis media: Part I. Improving diagnostic accuracy,” Am. Fam. Physician 61(7), 2051–2056 (2000).
[PubMed]

Podoleanu, A. G.

S. Van der Jeught, J. J. J. Dirckx, J. R. M. Aerts, A. Bradu, A. G. Podoleanu, and J. A. N. Buytaert, “Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography,” J. Assoc. Res. Otolaryngol. 14(4), 483–494 (2013).
[Crossref] [PubMed]

Poe, D. S.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Polani, S.

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

Porter, R. G.

G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
[Crossref] [PubMed]

Ravicz, M. E.

P. Razavi, M. E. Ravicz, I. Dobrev, J. T. Cheng, C. Furlong, and J. J. Rosowski, “Response of the human tympanic membrane to transient acoustic and mechanical stimuli: Preliminary results,” Hear. Res. 340, 15–24 (2016).
[Crossref] [PubMed]

Razavi, P.

P. Razavi, M. E. Ravicz, I. Dobrev, J. T. Cheng, C. Furlong, and J. J. Rosowski, “Response of the human tympanic membrane to transient acoustic and mechanical stimuli: Preliminary results,” Hear. Res. 340, 15–24 (2016).
[Crossref] [PubMed]

Revonta, M.

H. Lindén, H. Teppo, and M. Revonta, “Spectral gradient acoustic reflectometry in the diagnosis of middle-ear fluid in children,” Eur. Arch. Otorhinolaryngol. 264(5), 477–481 (2007).
[Crossref] [PubMed]

Rosenfeld, R. M.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Rosner, B. A.

D. W. Teele, J. O. Klein, and B. A. Rosner, “Otitis media with effusion during the first three years of life and development of speech and language,” Pediatrics 74(2), 282–287 (1984).
[PubMed]

Rosowski, J. J.

P. Razavi, M. E. Ravicz, I. Dobrev, J. T. Cheng, C. Furlong, and J. J. Rosowski, “Response of the human tympanic membrane to transient acoustic and mechanical stimuli: Preliminary results,” Hear. Res. 340, 15–24 (2016).
[Crossref] [PubMed]

Ruohola, A.

M. K. Laine, P. A. Tähtinen, K. K. Helenius, R. Luoto, and A. Ruohola, “Acoustic Reflectometry in Discrimination of Otoscopic Diagnoses in Young Ambulatory Children,” Pediatr. Infect. Dis. J. 31(10), 1007–1011 (2012).
[PubMed]

Sanz, M.

Schmilovitch, Z.

Schwartz, S. R.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Schwarz, A.

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

N. Ozana, S. Buchsbaum, Y. Bishitz, Y. Beiderman, Z. Schmilovitch, A. Schwarz, A. Shemer, J. Keshet, and Z. Zalevsky, “Optical remote sensor for peanut kernel abortion classification,” Appl. Opt. 55(15), 4005–4010 (2016).
[Crossref] [PubMed]

Sevil, E.

T. Muderris, A. Yazıcı, S. Bercin, G. Yalçıner, E. Sevil, and M. Kırıs, “Consumer acoustic reflectometry: accuracy in diagnosis of otitis media with effusion in children,” Int. J. Pediatr. Otorhinolaryngol. 77(10), 1771–1774 (2013).
[Crossref] [PubMed]

Shekelle, P.

G. S. Takata, L. S. Chan, T. Morphew, R. Mangione-Smith, S. C. Morton, and P. Shekelle, “Evidence Assessment of the Accuracy of Methods of Diagnosing Middle Ear Effusion in Children With Otitis Media With Effusion,” Pediatrics 112(6), 1379–1387 (2003).
[Crossref] [PubMed]

Shelton, R. L.

G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
[Crossref] [PubMed]

Shemer, A.

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

N. Ozana, S. Buchsbaum, Y. Bishitz, Y. Beiderman, Z. Schmilovitch, A. Schwarz, A. Shemer, J. Keshet, and Z. Zalevsky, “Optical remote sensor for peanut kernel abortion classification,” Appl. Opt. 55(15), 4005–4010 (2016).
[Crossref] [PubMed]

Shenhav, A.

A. Shenhav, Z. Brodie, Y. Beiderman, J. Garcia, V. Mico, and Z. Zalevsky, “Optical sensor for remote estimation of alcohol concentration in blood stream,” Opt. Commun. 289, 149–157 (2013).
[Crossref]

Shin, J. J.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Skaat, A.

Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).

Spillman, D. R.

G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
[Crossref] [PubMed]

Tähtinen, P. A.

M. K. Laine, P. A. Tähtinen, K. K. Helenius, R. Luoto, and A. Ruohola, “Acoustic Reflectometry in Discrimination of Otoscopic Diagnoses in Young Ambulatory Children,” Pediatr. Infect. Dis. J. 31(10), 1007–1011 (2012).
[PubMed]

Takata, G. S.

G. S. Takata, L. S. Chan, T. Morphew, R. Mangione-Smith, S. C. Morton, and P. Shekelle, “Evidence Assessment of the Accuracy of Methods of Diagnosing Middle Ear Effusion in Children With Otitis Media With Effusion,” Pediatrics 112(6), 1379–1387 (2003).
[Crossref] [PubMed]

Teele, D. W.

D. W. Teele, J. O. Klein, and B. A. Rosner, “Otitis media with effusion during the first three years of life and development of speech and language,” Pediatrics 74(2), 282–287 (1984).
[PubMed]

Teicher, M.

Y. Beiderman, I. Horovitz, N. Burshtein, M. Teicher, J. Garcia, V. Mico, and Z. Zalevsky, “Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern,” J. Biomed. Opt. 15(6), 061707 (2010).
[Crossref] [PubMed]

Z. Zalevsky, Y. Beiderman, I. Margalit, S. Gingold, M. Teicher, V. Mico, and J. Garcia, “Simultaneous remote extraction of multiple speech sources and heart beats from secondary speckles pattern,” Opt. Express 17(24), 21566–21580 (2009).
[Crossref] [PubMed]

Teppo, H.

H. Lindén, H. Teppo, and M. Revonta, “Spectral gradient acoustic reflectometry in the diagnosis of middle-ear fluid in children,” Eur. Arch. Otorhinolaryngol. 264(5), 477–481 (2007).
[Crossref] [PubMed]

Tornow, R.-P.

Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).

Tos, M.

M. Tos, “Epidemiology and natural history of secretory otitis,” Am. J. Otol. 5(6), 459–462 (1984).
[PubMed]

Van der Jeught, S.

S. Van der Jeught, J. J. J. Dirckx, J. R. M. Aerts, A. Bradu, A. G. Podoleanu, and J. A. N. Buytaert, “Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography,” J. Assoc. Res. Otolaryngol. 14(4), 483–494 (2013).
[Crossref] [PubMed]

Veling, M.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Vila, P. M.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Wallis, S.

H. Atkinson, S. Wallis, and A. P. Coatesworth, “Otitis media with effusion,” Postgrad. Med. 127(4), 381–385 (2015).
[Crossref] [PubMed]

Walsh, S. A.

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Wei, J.

Q. Zhang, J. Wei, and M. Xu “Prevalence of otitis media with effusion among children in Xi'an, China: a randomized survey in China's mainland,”, 120, 617–621 (2011).

Williamson, I.

I. Williamson, “Otitis media with effusion,” Clin. Evid. 7(7), 469–476 (2002).
[PubMed]

Wood, M. W.

R. Z. Gan, C. Dai, and M. W. Wood, “Laser interferometry measurements of middle ear fluid and pressure effects on sound transmission,” J. Acoust. Soc. Am. 120(6), 3799–3810 (2006).
[Crossref] [PubMed]

Xu, M.

Q. Zhang, J. Wei, and M. Xu “Prevalence of otitis media with effusion among children in Xi'an, China: a randomized survey in China's mainland,”, 120, 617–621 (2011).

Yalçiner, G.

T. Muderris, A. Yazıcı, S. Bercin, G. Yalçıner, E. Sevil, and M. Kırıs, “Consumer acoustic reflectometry: accuracy in diagnosis of otitis media with effusion in children,” Int. J. Pediatr. Otorhinolaryngol. 77(10), 1771–1774 (2013).
[Crossref] [PubMed]

Yazici, A.

T. Muderris, A. Yazıcı, S. Bercin, G. Yalçıner, E. Sevil, and M. Kırıs, “Consumer acoustic reflectometry: accuracy in diagnosis of otitis media with effusion in children,” Int. J. Pediatr. Otorhinolaryngol. 77(10), 1771–1774 (2013).
[Crossref] [PubMed]

Zalevsky, Z.

N. Ozana, Y. Bishitz, Y. Beiderman, J. Garcia, and Z. Zalevsky, “Remote optical configuration of pigmented lesion detection and diagnosis of bone fractures,” Proc. SPIE 9689, 968916 (2016).

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

N. Ozana, S. Buchsbaum, Y. Bishitz, Y. Beiderman, Z. Schmilovitch, A. Schwarz, A. Shemer, J. Keshet, and Z. Zalevsky, “Optical remote sensor for peanut kernel abortion classification,” Appl. Opt. 55(15), 4005–4010 (2016).
[Crossref] [PubMed]

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

N. Ozana, N. Arbel, Y. Beiderman, V. Mico, M. Sanz, J. Garcia, A. Anand, B. Javidi, Y. Epstein, and Z. Zalevsky, “Improved noncontact optical sensor for detection of glucose concentration and indication of dehydration level,” Biomed. Opt. Express 5(6), 1926–1940 (2014).
[Crossref] [PubMed]

A. Shenhav, Z. Brodie, Y. Beiderman, J. Garcia, V. Mico, and Z. Zalevsky, “Optical sensor for remote estimation of alcohol concentration in blood stream,” Opt. Commun. 289, 149–157 (2013).
[Crossref]

Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).

Y. Beiderman, I. Horovitz, N. Burshtein, M. Teicher, J. Garcia, V. Mico, and Z. Zalevsky, “Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern,” J. Biomed. Opt. 15(6), 061707 (2010).
[Crossref] [PubMed]

Z. Zalevsky, Y. Beiderman, I. Margalit, S. Gingold, M. Teicher, V. Mico, and J. Garcia, “Simultaneous remote extraction of multiple speech sources and heart beats from secondary speckles pattern,” Opt. Express 17(24), 21566–21580 (2009).
[Crossref] [PubMed]

Zhang, Q.

Q. Zhang, J. Wei, and M. Xu “Prevalence of otitis media with effusion among children in Xi'an, China: a randomized survey in China's mainland,”, 120, 617–621 (2011).

Am. Fam. Physician (1)

M. E. Pichichero, “Acute otitis media: Part I. Improving diagnostic accuracy,” Am. Fam. Physician 61(7), 2051–2056 (2000).
[PubMed]

Am. J. Otol. (1)

M. Tos, “Epidemiology and natural history of secretory otitis,” Am. J. Otol. 5(6), 459–462 (1984).
[PubMed]

Appl. Opt. (1)

Arch. Environ. Health (1)

M. Iversen, L. Birch, G. R. Lundqvist, and O. Elbrønd, “Middle ear effusion in children and the indoor environment: an epidemiological study,” Arch. Environ. Health 40(2), 74–79 (1985).
[Crossref] [PubMed]

Biomed. Opt. Express (1)

Clin. Evid. (1)

I. Williamson, “Otitis media with effusion,” Clin. Evid. 7(7), 469–476 (2002).
[PubMed]

Eur. Arch. Otorhinolaryngol. (1)

H. Lindén, H. Teppo, and M. Revonta, “Spectral gradient acoustic reflectometry in the diagnosis of middle-ear fluid in children,” Eur. Arch. Otorhinolaryngol. 264(5), 477–481 (2007).
[Crossref] [PubMed]

Fam. Med. (1)

J. E. MacClements, M. Parchman, and C. Passmore, “Otitis media in children: use of diagnostic tools by family practice residents,” Fam. Med. 34(8), 598–603 (2002).
[PubMed]

Hear. Res. (1)

P. Razavi, M. E. Ravicz, I. Dobrev, J. T. Cheng, C. Furlong, and J. J. Rosowski, “Response of the human tympanic membrane to transient acoustic and mechanical stimuli: Preliminary results,” Hear. Res. 340, 15–24 (2016).
[Crossref] [PubMed]

Int. J. Pediatr. Otorhinolaryngol. (2)

T. Muderris, A. Yazıcı, S. Bercin, G. Yalçıner, E. Sevil, and M. Kırıs, “Consumer acoustic reflectometry: accuracy in diagnosis of otitis media with effusion in children,” Int. J. Pediatr. Otorhinolaryngol. 77(10), 1771–1774 (2013).
[Crossref] [PubMed]

J. Lous and M. Fiellau-Nikolajsen, “Epidemiology and middle ear effusion and tubal dysfunction. a one-year prospective study comprising monthly tympanometry in 387 non-selected 7-year-old children,” Int. J. Pediatr. Otorhinolaryngol. 3(4), 303–317 (1981).
[Crossref] [PubMed]

Invest. Ophthalmol. Vis. Sci. (1)

Z. Zalevsky, I. Margalit, Y. Beiderman, A. Skaat, M. Belkin, R.-P. Tornow, V. Mico, and J. Garcia, “Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle,” Invest. Ophthalmol. Vis. Sci. 53, 1972 (2012).

J. Acoust. Soc. Am. (1)

R. Z. Gan, C. Dai, and M. W. Wood, “Laser interferometry measurements of middle ear fluid and pressure effects on sound transmission,” J. Acoust. Soc. Am. 120(6), 3799–3810 (2006).
[Crossref] [PubMed]

J. Assoc. Res. Otolaryngol. (1)

S. Van der Jeught, J. J. J. Dirckx, J. R. M. Aerts, A. Bradu, A. G. Podoleanu, and J. A. N. Buytaert, “Full-Field Thickness Distribution of Human Tympanic Membrane Obtained with Optical Coherence Tomography,” J. Assoc. Res. Otolaryngol. 14(4), 483–494 (2013).
[Crossref] [PubMed]

J. Biomed. Opt. (2)

Y. Beiderman, I. Horovitz, N. Burshtein, M. Teicher, J. Garcia, V. Mico, and Z. Zalevsky, “Remote estimation of blood pulse pressure via temporal tracking of reflected secondary speckles pattern,” J. Biomed. Opt. 15(6), 061707 (2010).
[Crossref] [PubMed]

N. Ozana, Y. Beiderman, A. Anand, B. Javidi, S. Polani, A. Schwarz, A. Shemer, J. Garcia, and Z. Zalevsky, “Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect,” J. Biomed. Opt. 21(6), 65001 (2016).
[Crossref] [PubMed]

J. Biophotonics (1)

G. L. Monroy, P. Pande, R. L. Shelton, R. M. Nolan, D. R. Spillman, R. G. Porter, M. A. Novak, and S. A. Boppart, “Non-invasive optical assessment of viscosity of middle ear effusions in otitis media,” J. Biophotonics 10(3), 394–403 (2017).
[Crossref] [PubMed]

J. Opt. Soc. Am. (1)

Laryngoscope (2)

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

M. L. Casselbrant, L. M. Brostoff, E. I. Cantekin, M. R. Flaherty, W. J. Doyle, C. D. Bluestone, and T. J. Fria, “Otitis media with effusion in preschool children,” Laryngoscope 95(4), 428–436 (1985).
[Crossref] [PubMed]

N. Engl. J. Med. (1)

S. Berman, “Otitis Media in Children,” N. Engl. J. Med. 332(23), 1560–1565 (1995).
[Crossref] [PubMed]

Opt. Commun. (1)

A. Shenhav, Z. Brodie, Y. Beiderman, J. Garcia, V. Mico, and Z. Zalevsky, “Optical sensor for remote estimation of alcohol concentration in blood stream,” Opt. Commun. 289, 149–157 (2013).
[Crossref]

Opt. Express (1)

Otolaryngol. Head Neck Surg. (1)

R. M. Rosenfeld, J. J. Shin, S. R. Schwartz, R. Coggins, L. Gagnon, J. M. Hackell, D. Hoelting, L. L. Hunter, A. W. Kummer, S. C. Payne, D. S. Poe, M. Veling, P. M. Vila, S. A. Walsh, and M. D. Corrigan, “Clinical Practice Guideline: Otitis Media with Effusion Executive Summary (Update),” Otolaryngol. Head Neck Surg. 154(2), 201–214 (2016).
[Crossref] [PubMed]

Pediatr. Infect. Dis. J. (1)

M. K. Laine, P. A. Tähtinen, K. K. Helenius, R. Luoto, and A. Ruohola, “Acoustic Reflectometry in Discrimination of Otoscopic Diagnoses in Young Ambulatory Children,” Pediatr. Infect. Dis. J. 31(10), 1007–1011 (2012).
[PubMed]

Pediatrics (2)

G. S. Takata, L. S. Chan, T. Morphew, R. Mangione-Smith, S. C. Morton, and P. Shekelle, “Evidence Assessment of the Accuracy of Methods of Diagnosing Middle Ear Effusion in Children With Otitis Media With Effusion,” Pediatrics 112(6), 1379–1387 (2003).
[Crossref] [PubMed]

D. W. Teele, J. O. Klein, and B. A. Rosner, “Otitis media with effusion during the first three years of life and development of speech and language,” Pediatrics 74(2), 282–287 (1984).
[PubMed]

Postgrad. Med. (1)

H. Atkinson, S. Wallis, and A. P. Coatesworth, “Otitis media with effusion,” Postgrad. Med. 127(4), 381–385 (2015).
[Crossref] [PubMed]

Proc. IEEE (1)

N. Ozana, I. Margalith, Y. Beiderman, M. Kunin, G. A. Campino, R. Gerasi, J. Garcia, V. Mico, and Z. Zalevsky, “Demonstration of a Remote Optical Measurement Configuration That Correlates with Breathing, Heart Rate, Pulse Pressure, Blood Coagulation, and Blood Oxygenation,” Proc. IEEE 103(2), 248–262 (2015).
[Crossref]

Proc. SPIE (1)

N. Ozana, Y. Bishitz, Y. Beiderman, J. Garcia, and Z. Zalevsky, “Remote optical configuration of pigmented lesion detection and diagnosis of bone fractures,” Proc. SPIE 9689, 968916 (2016).

Other (1)

Q. Zhang, J. Wei, and M. Xu “Prevalence of otitis media with effusion among children in Xi'an, China: a randomized survey in China's mainland,”, 120, 617–621 (2011).

Cited By

OSA participates in Crossref's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (15)

Fig. 1
Fig. 1 (a) Schematic sketch of the system. (b) The optical configuration for remote sensing of middle ear effusion.
Fig. 2
Fig. 2 Summary of the presented method for detection of middle ear effusion.
Fig. 3
Fig. 3 The optical response of a healthy eardrum.
Fig. 4
Fig. 4 Frequency response of diagnosed OM denoted with (a). Frequency response of healthy eardrum denoted with (b).
Fig. 5
Fig. 5 The optical configuration of the in vitro test
Fig. 6
Fig. 6 The frequency response of SSM while the surrounding is (a) air and (b) water. The mean and the standard deviation of 10 different experiments are shown in (c).
Fig. 7
Fig. 7 The correlation value of 5 samples with different agarose concentration.
Fig. 8
Fig. 8 An exponential fit for the averaged correlation functions.
Fig. 9
Fig. 9 An exponential fit for the averaged correlation functions.
Fig. 10
Fig. 10 The frequency response of a healthy ear drum for (a) 155Hz (b) 255Hz and (c) 355Hz excitation frequency with respect to middle ear effusion response at the same frequencies (d – f).
Fig. 11
Fig. 11 The optical unique signature of healthy ear drums and of ear drums with middle ear effusion.
Fig. 12
Fig. 12 The optical unique signature of healthy ear drum with respect to middle ear effusion of 5 difference subjects.
Fig. 13
Fig. 13 Normalized energy of the frequency response at the excitation frequencies of middle ear effusion in contrast to healthy eardrums. Five different subjects’ results denoted with (a-e) each present a clear contrast between healthy and middle ear effusion cases.
Fig. 14
Fig. 14 Decay time of a healthy eardrum denoted by (a) and ear effusion denoted by (b).
Fig. 15
Fig. 15 Decay time of middle ear effusions with respect to healthy eardrums. Five different subjects’ results denoted with (a-e) each present the decay time of healthy and middle ear effusion cases.

Tables (1)

Tables Icon

Table 1 Summary of subject information.

Equations (4)

Equations on this page are rendered with MathJax. Learn more.

A( x 0 , y 0 )=| exp[iϕ (x,y)]exp[i( β x x+ β y y)exp[ πi λZ ( (x x 0 ) 2 + (y y 0 ) 2 )]dxdy |
β= 4πtanα λ
A( x x 0 , y x 0 )=| exp[iϕ (x,y)]exp[i( β x x+ β y y)exp[ πi λZ (x x 0 +y y 0 )]dxdy |
D 2 λ <Z

Metrics