Abstract

A fibre optic surface plasmon resonance (SPR) sensor system for smartphones is reported, for the first time. The sensor was fabricated by using an easy-to-implement silver coating technique and by polishing both ends of a 400 µm optical fibre to obtain 45° end-faces. For excitation and interrogation of the SPR sensor system the flash-light and camera at the back side of the smartphone were employed, respectively. Consequently, no external electrical components are required for the operation of the sensor system developed. In a first application example a refractive index sensor was realised. The performance of the SPR sensor system was demonstrated by using different volume concentrations of glycerol solution. A sensitivity of 5.96·10−4 refractive index units (RIU)/pixel was obtained for a refractive index (RI) range from 1.33 to 1.36. In future implementations the reported sensor system could be integrated in a cover of a smartphone or used as a low-cost, portable point-of-care diagnostic platform. Consequently it offers the potential of monitoring a large variety of environmental or point-of-care parameters in combination with smartphones.

© 2015 Optical Society of America

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  1. S. K. Vashist, O. Mudanyali, E. M. Schneider, R. Zengerle, and A. Ozcan, “Cellphone-based devices for bioanalytical sciences,” Anal. Bioanal. Chem. 406(14), 3263–3277 (2014).
    [Crossref] [PubMed]
  2. H. Zhu, O. Yaglidere, T. W. Su, D. Tseng, and A. Ozcan, “Cost-effective and compact wide-field fluorescent imaging on a cell-phone,” Lab Chip 11(2), 315–322 (2011).
    [Crossref] [PubMed]
  3. D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, “Lensfree microscopy on a cellphone,” Lab Chip 10(14), 1787–1792 (2010).
    [Crossref] [PubMed]
  4. A. F. Coskun, J. Wong, D. Khodadadi, R. Nagi, A. Tey, and A. Ozcan, “A personalized food allergen testing platform on a cellphone,” Lab Chip 13(4), 636–640 (2013).
    [Crossref] [PubMed]
  5. A. F. Coskun, R. Nagi, K. Sadeghi, S. Phillips, and A. Ozcan, “Albumin testing in urine using a smart-phone,” Lab Chip 13(21), 4231–4238 (2013).
    [Crossref] [PubMed]
  6. A. Ozcan, “Mobile phones democratize and cultivate next-generation imaging, diagnostics and measurement tools,” Lab Chip 14(17), 3187–3194 (2014).
    [Crossref] [PubMed]
  7. P. Preechaburana, A. Suska, and D. Filippini, “Embedded adaptive optics for ubiquitous lab-on-a-chip readout on intact cell phones,” Sensors (Basel) 12(7), 8586–8600 (2012).
    [Crossref] [PubMed]
  8. J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
    [Crossref] [PubMed]
  9. S. X. Wang and X. J. Zhou, “Spectroscopic sensor on mobile phone,” US Patent 7420663 B2 (September 2, 2008).
  10. D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
    [Crossref] [PubMed]
  11. S. Dutta, A. Choudhury, and P. Nath, “Evanescent wave coupled spectroscopic sensing using smartphone,” IEEE Photon. Technol. Lett. 26(6), 568–570 (2014).
    [Crossref]
  12. P. Preechaburana, M. C. Gonzalez, A. Suska, and D. Filippini, “Surface plasmon resonance chemical sensing on cell phones,” Angew. Chem. Int. Ed. Engl. 51(46), 11585–11588 (2012).
    [Crossref] [PubMed]
  13. C. A. de Souza Filho, A. M. N. Lima, and H. Neff, “Smartphone based, portable optical biosensor utilizing surface plasmon resonance,” in Proceedings of IEEE Conference on Instrumentation and Measurement Technology (IEEE, 2014), pp. 890–895.
    [Crossref]
  14. J. Homola, Surface Plasmon Resonance Based Sensors (Springer, 2006)
  15. W. Peng, Y. Liu, P. Fang, X. Liu, Z. Gong, H. Wang, and F. Cheng, “Compact surface plasmon resonance imaging sensing system based on general optoelectronic components,” Opt. Express 22(5), 6174–6185 (2014).
    [Crossref] [PubMed]
  16. A. Pal, R. Sen, K. Bremer, S. Yao, E. Lewis, T. Sun, and K. T. V. Grattan, “All-fiber’ tunable laser in the 2 μm region, designed for CO2 detection,” Appl. Opt. 51(29), 7011–7015 (2012).
    [Crossref] [PubMed]
  17. Y. Zhao, Z. Deng, and Q. Wang, “Fiber optic SPR sensor for liquid concentration measurement,” Sens. Actuators B Chem. 192, 229–233 (2014).
    [Crossref]

2014 (5)

S. K. Vashist, O. Mudanyali, E. M. Schneider, R. Zengerle, and A. Ozcan, “Cellphone-based devices for bioanalytical sciences,” Anal. Bioanal. Chem. 406(14), 3263–3277 (2014).
[Crossref] [PubMed]

A. Ozcan, “Mobile phones democratize and cultivate next-generation imaging, diagnostics and measurement tools,” Lab Chip 14(17), 3187–3194 (2014).
[Crossref] [PubMed]

S. Dutta, A. Choudhury, and P. Nath, “Evanescent wave coupled spectroscopic sensing using smartphone,” IEEE Photon. Technol. Lett. 26(6), 568–570 (2014).
[Crossref]

W. Peng, Y. Liu, P. Fang, X. Liu, Z. Gong, H. Wang, and F. Cheng, “Compact surface plasmon resonance imaging sensing system based on general optoelectronic components,” Opt. Express 22(5), 6174–6185 (2014).
[Crossref] [PubMed]

Y. Zhao, Z. Deng, and Q. Wang, “Fiber optic SPR sensor for liquid concentration measurement,” Sens. Actuators B Chem. 192, 229–233 (2014).
[Crossref]

2013 (3)

D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
[Crossref] [PubMed]

A. F. Coskun, J. Wong, D. Khodadadi, R. Nagi, A. Tey, and A. Ozcan, “A personalized food allergen testing platform on a cellphone,” Lab Chip 13(4), 636–640 (2013).
[Crossref] [PubMed]

A. F. Coskun, R. Nagi, K. Sadeghi, S. Phillips, and A. Ozcan, “Albumin testing in urine using a smart-phone,” Lab Chip 13(21), 4231–4238 (2013).
[Crossref] [PubMed]

2012 (3)

P. Preechaburana, M. C. Gonzalez, A. Suska, and D. Filippini, “Surface plasmon resonance chemical sensing on cell phones,” Angew. Chem. Int. Ed. Engl. 51(46), 11585–11588 (2012).
[Crossref] [PubMed]

P. Preechaburana, A. Suska, and D. Filippini, “Embedded adaptive optics for ubiquitous lab-on-a-chip readout on intact cell phones,” Sensors (Basel) 12(7), 8586–8600 (2012).
[Crossref] [PubMed]

A. Pal, R. Sen, K. Bremer, S. Yao, E. Lewis, T. Sun, and K. T. V. Grattan, “All-fiber’ tunable laser in the 2 μm region, designed for CO2 detection,” Appl. Opt. 51(29), 7011–7015 (2012).
[Crossref] [PubMed]

2011 (1)

H. Zhu, O. Yaglidere, T. W. Su, D. Tseng, and A. Ozcan, “Cost-effective and compact wide-field fluorescent imaging on a cell-phone,” Lab Chip 11(2), 315–322 (2011).
[Crossref] [PubMed]

2010 (1)

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, “Lensfree microscopy on a cellphone,” Lab Chip 10(14), 1787–1792 (2010).
[Crossref] [PubMed]

2009 (1)

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Agirregabiria, M.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Bang, D. D.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Berganzo, J.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Bremer, K.

Bu, M.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Cheng, F.

Choudhury, A.

S. Dutta, A. Choudhury, and P. Nath, “Evanescent wave coupled spectroscopic sensing using smartphone,” IEEE Photon. Technol. Lett. 26(6), 568–570 (2014).
[Crossref]

Clark, P. P.

D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
[Crossref] [PubMed]

Coskun, A. F.

A. F. Coskun, R. Nagi, K. Sadeghi, S. Phillips, and A. Ozcan, “Albumin testing in urine using a smart-phone,” Lab Chip 13(21), 4231–4238 (2013).
[Crossref] [PubMed]

A. F. Coskun, J. Wong, D. Khodadadi, R. Nagi, A. Tey, and A. Ozcan, “A personalized food allergen testing platform on a cellphone,” Lab Chip 13(4), 636–640 (2013).
[Crossref] [PubMed]

Cunningham, B. T.

D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
[Crossref] [PubMed]

de Souza Filho, C. A.

C. A. de Souza Filho, A. M. N. Lima, and H. Neff, “Smartphone based, portable optical biosensor utilizing surface plasmon resonance,” in Proceedings of IEEE Conference on Instrumentation and Measurement Technology (IEEE, 2014), pp. 890–895.
[Crossref]

Deng, Z.

Y. Zhao, Z. Deng, and Q. Wang, “Fiber optic SPR sensor for liquid concentration measurement,” Sens. Actuators B Chem. 192, 229–233 (2014).
[Crossref]

Dutta, S.

S. Dutta, A. Choudhury, and P. Nath, “Evanescent wave coupled spectroscopic sensing using smartphone,” IEEE Photon. Technol. Lett. 26(6), 568–570 (2014).
[Crossref]

Dziuban, J. A.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Fang, P.

Filippini, D.

P. Preechaburana, M. C. Gonzalez, A. Suska, and D. Filippini, “Surface plasmon resonance chemical sensing on cell phones,” Angew. Chem. Int. Ed. Engl. 51(46), 11585–11588 (2012).
[Crossref] [PubMed]

P. Preechaburana, A. Suska, and D. Filippini, “Embedded adaptive optics for ubiquitous lab-on-a-chip readout on intact cell phones,” Sensors (Basel) 12(7), 8586–8600 (2012).
[Crossref] [PubMed]

Gallegos, D.

D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
[Crossref] [PubMed]

George, S.

D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
[Crossref] [PubMed]

Gong, Z.

Gonzalez, M. C.

P. Preechaburana, M. C. Gonzalez, A. Suska, and D. Filippini, “Surface plasmon resonance chemical sensing on cell phones,” Angew. Chem. Int. Ed. Engl. 51(46), 11585–11588 (2012).
[Crossref] [PubMed]

Grattan, K. T. V.

Isikman, S. O.

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, “Lensfree microscopy on a cellphone,” Lab Chip 10(14), 1787–1792 (2010).
[Crossref] [PubMed]

Khodadadi, D.

A. F. Coskun, J. Wong, D. Khodadadi, R. Nagi, A. Tey, and A. Ozcan, “A personalized food allergen testing platform on a cellphone,” Lab Chip 13(4), 636–640 (2013).
[Crossref] [PubMed]

Lewis, E.

Lima, A. M. N.

C. A. de Souza Filho, A. M. N. Lima, and H. Neff, “Smartphone based, portable optical biosensor utilizing surface plasmon resonance,” in Proceedings of IEEE Conference on Instrumentation and Measurement Technology (IEEE, 2014), pp. 890–895.
[Crossref]

Lin, Y.

D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
[Crossref] [PubMed]

Liu, X.

Liu, Y.

Long, K. D.

D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
[Crossref] [PubMed]

Mudanyali, O.

S. K. Vashist, O. Mudanyali, E. M. Schneider, R. Zengerle, and A. Ozcan, “Cellphone-based devices for bioanalytical sciences,” Anal. Bioanal. Chem. 406(14), 3263–3277 (2014).
[Crossref] [PubMed]

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, “Lensfree microscopy on a cellphone,” Lab Chip 10(14), 1787–1792 (2010).
[Crossref] [PubMed]

Nagi, R.

A. F. Coskun, J. Wong, D. Khodadadi, R. Nagi, A. Tey, and A. Ozcan, “A personalized food allergen testing platform on a cellphone,” Lab Chip 13(4), 636–640 (2013).
[Crossref] [PubMed]

A. F. Coskun, R. Nagi, K. Sadeghi, S. Phillips, and A. Ozcan, “Albumin testing in urine using a smart-phone,” Lab Chip 13(21), 4231–4238 (2013).
[Crossref] [PubMed]

Nath, P.

S. Dutta, A. Choudhury, and P. Nath, “Evanescent wave coupled spectroscopic sensing using smartphone,” IEEE Photon. Technol. Lett. 26(6), 568–570 (2014).
[Crossref]

D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
[Crossref] [PubMed]

Neff, H.

C. A. de Souza Filho, A. M. N. Lima, and H. Neff, “Smartphone based, portable optical biosensor utilizing surface plasmon resonance,” in Proceedings of IEEE Conference on Instrumentation and Measurement Technology (IEEE, 2014), pp. 890–895.
[Crossref]

Olabarria, G.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Ozcan, A.

A. Ozcan, “Mobile phones democratize and cultivate next-generation imaging, diagnostics and measurement tools,” Lab Chip 14(17), 3187–3194 (2014).
[Crossref] [PubMed]

S. K. Vashist, O. Mudanyali, E. M. Schneider, R. Zengerle, and A. Ozcan, “Cellphone-based devices for bioanalytical sciences,” Anal. Bioanal. Chem. 406(14), 3263–3277 (2014).
[Crossref] [PubMed]

A. F. Coskun, R. Nagi, K. Sadeghi, S. Phillips, and A. Ozcan, “Albumin testing in urine using a smart-phone,” Lab Chip 13(21), 4231–4238 (2013).
[Crossref] [PubMed]

A. F. Coskun, J. Wong, D. Khodadadi, R. Nagi, A. Tey, and A. Ozcan, “A personalized food allergen testing platform on a cellphone,” Lab Chip 13(4), 636–640 (2013).
[Crossref] [PubMed]

H. Zhu, O. Yaglidere, T. W. Su, D. Tseng, and A. Ozcan, “Cost-effective and compact wide-field fluorescent imaging on a cell-phone,” Lab Chip 11(2), 315–322 (2011).
[Crossref] [PubMed]

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, “Lensfree microscopy on a cellphone,” Lab Chip 10(14), 1787–1792 (2010).
[Crossref] [PubMed]

Oztoprak, C.

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, “Lensfree microscopy on a cellphone,” Lab Chip 10(14), 1787–1792 (2010).
[Crossref] [PubMed]

Pal, A.

Peng, W.

Phillips, S.

A. F. Coskun, R. Nagi, K. Sadeghi, S. Phillips, and A. Ozcan, “Albumin testing in urine using a smart-phone,” Lab Chip 13(21), 4231–4238 (2013).
[Crossref] [PubMed]

Preechaburana, P.

P. Preechaburana, A. Suska, and D. Filippini, “Embedded adaptive optics for ubiquitous lab-on-a-chip readout on intact cell phones,” Sensors (Basel) 12(7), 8586–8600 (2012).
[Crossref] [PubMed]

P. Preechaburana, M. C. Gonzalez, A. Suska, and D. Filippini, “Surface plasmon resonance chemical sensing on cell phones,” Angew. Chem. Int. Ed. Engl. 51(46), 11585–11588 (2012).
[Crossref] [PubMed]

Ruano-López, J. M.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Sadeghi, K.

A. F. Coskun, R. Nagi, K. Sadeghi, S. Phillips, and A. Ozcan, “Albumin testing in urine using a smart-phone,” Lab Chip 13(21), 4231–4238 (2013).
[Crossref] [PubMed]

Schneider, E. M.

S. K. Vashist, O. Mudanyali, E. M. Schneider, R. Zengerle, and A. Ozcan, “Cellphone-based devices for bioanalytical sciences,” Anal. Bioanal. Chem. 406(14), 3263–3277 (2014).
[Crossref] [PubMed]

Sen, R.

Sencan, I.

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, “Lensfree microscopy on a cellphone,” Lab Chip 10(14), 1787–1792 (2010).
[Crossref] [PubMed]

Su, T. W.

H. Zhu, O. Yaglidere, T. W. Su, D. Tseng, and A. Ozcan, “Cost-effective and compact wide-field fluorescent imaging on a cell-phone,” Lab Chip 11(2), 315–322 (2011).
[Crossref] [PubMed]

Sun, T.

Suska, A.

P. Preechaburana, M. C. Gonzalez, A. Suska, and D. Filippini, “Surface plasmon resonance chemical sensing on cell phones,” Angew. Chem. Int. Ed. Engl. 51(46), 11585–11588 (2012).
[Crossref] [PubMed]

P. Preechaburana, A. Suska, and D. Filippini, “Embedded adaptive optics for ubiquitous lab-on-a-chip readout on intact cell phones,” Sensors (Basel) 12(7), 8586–8600 (2012).
[Crossref] [PubMed]

Tey, A.

A. F. Coskun, J. Wong, D. Khodadadi, R. Nagi, A. Tey, and A. Ozcan, “A personalized food allergen testing platform on a cellphone,” Lab Chip 13(4), 636–640 (2013).
[Crossref] [PubMed]

Tseng, D.

H. Zhu, O. Yaglidere, T. W. Su, D. Tseng, and A. Ozcan, “Cost-effective and compact wide-field fluorescent imaging on a cell-phone,” Lab Chip 11(2), 315–322 (2011).
[Crossref] [PubMed]

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, “Lensfree microscopy on a cellphone,” Lab Chip 10(14), 1787–1792 (2010).
[Crossref] [PubMed]

Vashist, S. K.

S. K. Vashist, O. Mudanyali, E. M. Schneider, R. Zengerle, and A. Ozcan, “Cellphone-based devices for bioanalytical sciences,” Anal. Bioanal. Chem. 406(14), 3263–3277 (2014).
[Crossref] [PubMed]

Verdoy, D.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Voigt, A.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Walczak, R.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Wang, H.

Wang, Q.

Y. Zhao, Z. Deng, and Q. Wang, “Fiber optic SPR sensor for liquid concentration measurement,” Sens. Actuators B Chem. 192, 229–233 (2014).
[Crossref]

Wolff, A.

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

Wong, J.

A. F. Coskun, J. Wong, D. Khodadadi, R. Nagi, A. Tey, and A. Ozcan, “A personalized food allergen testing platform on a cellphone,” Lab Chip 13(4), 636–640 (2013).
[Crossref] [PubMed]

Yaglidere, O.

H. Zhu, O. Yaglidere, T. W. Su, D. Tseng, and A. Ozcan, “Cost-effective and compact wide-field fluorescent imaging on a cell-phone,” Lab Chip 11(2), 315–322 (2011).
[Crossref] [PubMed]

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, “Lensfree microscopy on a cellphone,” Lab Chip 10(14), 1787–1792 (2010).
[Crossref] [PubMed]

Yao, S.

Yu, H.

D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
[Crossref] [PubMed]

Zengerle, R.

S. K. Vashist, O. Mudanyali, E. M. Schneider, R. Zengerle, and A. Ozcan, “Cellphone-based devices for bioanalytical sciences,” Anal. Bioanal. Chem. 406(14), 3263–3277 (2014).
[Crossref] [PubMed]

Zhao, Y.

Y. Zhao, Z. Deng, and Q. Wang, “Fiber optic SPR sensor for liquid concentration measurement,” Sens. Actuators B Chem. 192, 229–233 (2014).
[Crossref]

Zhu, H.

H. Zhu, O. Yaglidere, T. W. Su, D. Tseng, and A. Ozcan, “Cost-effective and compact wide-field fluorescent imaging on a cell-phone,” Lab Chip 11(2), 315–322 (2011).
[Crossref] [PubMed]

Anal. Bioanal. Chem. (1)

S. K. Vashist, O. Mudanyali, E. M. Schneider, R. Zengerle, and A. Ozcan, “Cellphone-based devices for bioanalytical sciences,” Anal. Bioanal. Chem. 406(14), 3263–3277 (2014).
[Crossref] [PubMed]

Angew. Chem. Int. Ed. Engl. (1)

P. Preechaburana, M. C. Gonzalez, A. Suska, and D. Filippini, “Surface plasmon resonance chemical sensing on cell phones,” Angew. Chem. Int. Ed. Engl. 51(46), 11585–11588 (2012).
[Crossref] [PubMed]

Appl. Opt. (1)

IEEE Photon. Technol. Lett. (1)

S. Dutta, A. Choudhury, and P. Nath, “Evanescent wave coupled spectroscopic sensing using smartphone,” IEEE Photon. Technol. Lett. 26(6), 568–570 (2014).
[Crossref]

Lab Chip (7)

D. Gallegos, K. D. Long, H. Yu, P. P. Clark, Y. Lin, S. George, P. Nath, and B. T. Cunningham, “Label-free biodetection using a smartphone,” Lab Chip 13(11), 2124–2132 (2013).
[Crossref] [PubMed]

J. M. Ruano-López, M. Agirregabiria, G. Olabarria, D. Verdoy, D. D. Bang, M. Bu, A. Wolff, A. Voigt, J. A. Dziuban, R. Walczak, and J. Berganzo, “The SmartBioPhone™, a point of care vision under development through two European projects: OPTOLABCARD and LABONFOIL,” Lab Chip 9(11), 1495–1499 (2009).
[Crossref] [PubMed]

H. Zhu, O. Yaglidere, T. W. Su, D. Tseng, and A. Ozcan, “Cost-effective and compact wide-field fluorescent imaging on a cell-phone,” Lab Chip 11(2), 315–322 (2011).
[Crossref] [PubMed]

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, “Lensfree microscopy on a cellphone,” Lab Chip 10(14), 1787–1792 (2010).
[Crossref] [PubMed]

A. F. Coskun, J. Wong, D. Khodadadi, R. Nagi, A. Tey, and A. Ozcan, “A personalized food allergen testing platform on a cellphone,” Lab Chip 13(4), 636–640 (2013).
[Crossref] [PubMed]

A. F. Coskun, R. Nagi, K. Sadeghi, S. Phillips, and A. Ozcan, “Albumin testing in urine using a smart-phone,” Lab Chip 13(21), 4231–4238 (2013).
[Crossref] [PubMed]

A. Ozcan, “Mobile phones democratize and cultivate next-generation imaging, diagnostics and measurement tools,” Lab Chip 14(17), 3187–3194 (2014).
[Crossref] [PubMed]

Opt. Express (1)

Sens. Actuators B Chem. (1)

Y. Zhao, Z. Deng, and Q. Wang, “Fiber optic SPR sensor for liquid concentration measurement,” Sens. Actuators B Chem. 192, 229–233 (2014).
[Crossref]

Sensors (Basel) (1)

P. Preechaburana, A. Suska, and D. Filippini, “Embedded adaptive optics for ubiquitous lab-on-a-chip readout on intact cell phones,” Sensors (Basel) 12(7), 8586–8600 (2012).
[Crossref] [PubMed]

Other (3)

S. X. Wang and X. J. Zhou, “Spectroscopic sensor on mobile phone,” US Patent 7420663 B2 (September 2, 2008).

C. A. de Souza Filho, A. M. N. Lima, and H. Neff, “Smartphone based, portable optical biosensor utilizing surface plasmon resonance,” in Proceedings of IEEE Conference on Instrumentation and Measurement Technology (IEEE, 2014), pp. 890–895.
[Crossref]

J. Homola, Surface Plasmon Resonance Based Sensors (Springer, 2006)

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Figures (6)

Fig. 1
Fig. 1 Schematic of the fibre optic SPR sensor system for Smartphones.

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Fig. 2
Fig. 2 Interrogation system used to verify the fabricated fibre optic SPR sensors (a) and measured spectrum of a fabricated fibre optic SPR sensor at different RI (b).

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Fig. 3
Fig. 3 Picture of the fibre optic SPR sensor system realised in this work.

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Fig. 4
Fig. 4 RGB picture of the transmitted light of the fibre optic SPR sensor system (a) and greyscaled values of row 200 of the RGB picture (b).

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Fig. 5
Fig. 5 Change of the SPR due to different RI of the surrounding (a) and dependence of the SPR position to the RI of the surrounding (b) captured by the smartphone camera.

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Fig. 6
Fig. 6 Enhanced sensitivity achieved by increasing the resolution of the smartphone camera.

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Tables (1)

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Table 1 RI of the glycerol solutions used for sensor characterization.

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