Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Hybrid reconstruction method for multispectral bioluminescence tomography with log-sum regularization

Not Accessible

Your library or personal account may give you access

Abstract

Bioluminescence tomography (BLT) has important applications in the in vivo visualization of a pathological process for preclinical studies. However, the reconstruction of BLT is severely ill-posed. To recover the bioluminescence source stably and efficiently, we use a log-sum regularization term in the objective function and utilize a hybrid optimization algorithm for solving the nonconvex regularized problems (HONOR). The hybrid optimization scheme of HONOR merges second-order information and first-order information to reconstruction by choosing either the quasi-Newton (QN) or gradient descent step at each iteration. The QN step uses the limited-memory Broyden–Fletcher–Goldfarb–Shanno algorithm (L-BFGS) to acquire second-order information. Simulations and in vivo experiments based on multispectral measurements demonstrated the remarkable performance of the proposed hybrid method in the sparse reconstruction of BLT.

© 2020 Optical Society of America

Full Article  |  PDF Article
More Like This
Accurate and fast reconstruction for bioluminescence tomography based on adaptive Newton hard thresholding pursuit algorithm

Yuejie Wang, Heng Zhang, Hongbo Guo, Beilei Wang, Yanqiu Liu, Xuelei He, Jingjing Yu, Huangjian Yi, and Xiaowei He
J. Opt. Soc. Am. A 39(5) 829-840 (2022)

Comparative studies of lp-regularization-based reconstruction algorithms for bioluminescence tomography

Qitan Zhang, Xueli Chen, Xiaochao Qu, Jimin Liang, and Jie Tian
Biomed. Opt. Express 3(11) 2916-2936 (2012)

Sparse reconstruction for quantitative bioluminescence tomography based on the incomplete variables truncated conjugate gradient method

Xiaowei He, Jimin Liang, Xiaorui Wang, Jingjing Yu, Xiaochao Qu, Xiaodong Wang, Yanbin Hou, Duofang Chen, Fang Liu, and Jie Tian
Opt. Express 18(24) 24825-24841 (2010)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (6)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Tables (7)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (17)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved