Abstract
We established a protocol using a well-established LED stimulator to measure temporal contrast sensitivities driven by sine-wave modulation of L- and M-cones in the perifovea using triple silent substitution. The stimulus was presented in an annular field (2° inner diameter, 13° outer diameter). We validated this technique by studying the contrast sensitivity of three color normal observers at 10 different temporal frequencies (between 1 and 28 Hz) over a large range of retinal illuminances (between 0.07 and 587 phot Td), spanning the complete mesopic range. In one subject, sensitivities to counterphase modulation of L- and M-cones and in-phase modulation of L, M, and S-cones were additionally measured, which putatively reflected the parvo- and magnocellular retinogeniculate pathways, respectively. Furthermore, we performed measurements of temporal contrast sensitivities as a function of frequency at 294 phot Td in two protanopes, in two deuteranopes, and in one subject with S-cone monochromacy. Quality of isolation was satisfactory and we were able to reproduce known physiological patterns of temporal vision, such as the typical temporal contrast sensitivity functions of the L- and M-cone, the parvo- and magnocellular retinogeniculate pathways, as well as the light adaptation curves. These results will help determine optimal stimulus conditions in future studies. Results from the dichromats and the S-cone monochromat also support the quality of isolation of our protocol and underpin its potential clinical value.
© 2016 Optical Society of America
Full Article | PDF ArticleMore Like This
Cord Huchzermeyer and Jan Kremers
J. Opt. Soc. Am. A 34(2) 171-183 (2017)
Cord Huchzermeyer, Cristiane M. G. Martins, Balázs Nagy, Mirella T. S. Barboni, Dora F. Ventura, Marcelo F. Costa, and Jan Kremers
J. Opt. Soc. Am. A 35(4) B106-B113 (2018)
Vivianne C. Smith, Joel Pokorny, Monica Davis, and Tsaiyao Yeh
J. Opt. Soc. Am. A 12(2) 241-249 (1995)