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Effect of aging on multifocal oscillatory potentials

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Abstract

Multifocal oscillatory potentials (m-OPs) are thought to reflect rod–cone interactions. We examined the effect of age on the topography of the m-OP responses out to an eccentricity of 30 deg. Fifty-eight normal subjects were studied, aged between 13.6 and 58.8 yr. The data show a linear decrease in amplitude and a linear increase in latency with age, which is significant for most potentials. The decrease is uniform over the retina. These results suggest that an age-related impairment is occurring at or before the inner retina.

© 2002 Optical Society of America

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