Abstract
The multifocal electroretinogram (MERG) was recorded in the central 36°-diameter field in 26 young (19–30 yr) and 20 old (60–74 yr) adults in normal retinal health according to a fundus grading scale. The mean amplitude densities of the first-order and second-order responses in this retinal region were lower for old adults compared with young. The aging-related reduction of the first-order amplitude density was greatest at the fovea and decreased as a function of eccentricity. Similarly, the amplitudes of the first negative and positive peaks of the first-order MERG waveform were reduced with age, and the pattern of reduction followed a similar eccentricity dependency. The aging-related changes in the MERG waveform may be due to slowed temporal adaptation in the aged retina.
© 2002 Optical Society of America
Full Article | PDF ArticleMore Like This
Brad Fortune and Chris A. Johnson
J. Opt. Soc. Am. A 19(1) 173-184 (2002)
Anne Kurtenbach and Monika Weiss
J. Opt. Soc. Am. A 19(1) 190-196 (2002)
Keizo Shinomori, Athanasios Panorgias, and John S. Werner
J. Opt. Soc. Am. A 35(4) B26-B34 (2018)