Abstract

Our previous study showed that switching the inhaled gas from hypoxic gas to hyperoxic gas for 10 minutes increased tumor oxygenation and that the magnitude of oxyhemoglobin increase responded earlier than tumor volume change after chemotherapy. During 10 minutes of inhaled-oxygen modulation, oxyhemoglobin concentration first shows a rapid increase and then a slow but gradual increase, which has been fitted with a double-exponential equation in this study. Two amplitude values, amplitudes 1 and 2, respectively represent the magnitudes of rapid and slow increase of oxyhemoglobin. The trends of changes in amplitudes 1 and 2 were different, depending on tumor volume when chemotherapy started. However, both amplitudes 1 and 2 changed earlier than tumor volume, regardless of when chemotherapy was initiated. These results imply that by observing amplitude 1 changes post chemotherapy, we can reduce the time of a respiratory challenge from 10 minutes to less than 2 minutes, to see the chemotherapy response. We believe that by reducing the time of the respiratory challenge, we have taken a step forward to translating our previous study into clinical application.

© 2018 Optical Society of Korea

PDF Article

References

  • View by:
  • |
  • |
  • |

  1. A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
    [Crossref]
  2. R. H. Thomlinson and L. H. Gray, “The histological strucutre of some human lung cancers and the possible implications for radiotherapy,” Br. J. Cancer 9, 539-549 (1955).
    [Crossref]
  3. J. D. Chapman, C. C. Stobbe, M. R. Arnfield, R. Santus, J. Lee, and M. S. McPhee, “Oxygen dependency of tumor cell killing in vitro by light activated photofrin II,” Radiat. Res. 126, 73-79 (1991).
    [Crossref]
  4. B. Teicher, J. Lazo, and A. Sartorelli, “Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells,” Cancer Res. 41, 73-81 (1981).
  5. J. W. Denham, E. K. Yeoh, G. Wittwer, G. G. Ward, A. S. Ahmad, and N. D. Harvey, “Radiation therapy in hyperbaric oxygen for head and neck cancer at Royal Adelaide Hospital-1964 to 1980,” Int. J. Radiat. Oncol., Biol., Phys. 13, 201-208 (1987).
  6. R. J. Whittle, A. P. Fuller, and R. R. Foley, “Glottic cancer: results of treatment with radiotherapy in air and hyperbaric oxygen,” Clin. Oncol. 2, 214-219 (1990)
    [Crossref]
  7. E. Kjellen, M. C. Joiner, J. M. Collier, H. Johns, and A. Rojas, “A theraperutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments,” Radiother. Oncol. 22, 81-91 (1991).
    [Crossref]
  8. L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
    [Crossref]
  9. V. M. Laurence, R. Ward, I. F. Dennis, and N. M. Bleehen, “Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients,” Br. J. Cancer 72, 198-205 (1995).
    [Crossref]
  10. H. Liu, Y. Song, K. L. Worden, X. Jiang, A. Constantinescu, and R. P. Mason, “Noninvasive investigation of blood oxygenation dynamics of tumors by near-infrared spectroscopy,” Appl. Opt. 39, 5231-5243 (2000).
    [Crossref]
  11. J. G. Kim, D. Zhao, Y. Song, A. Constantinescu, R. P. Mason, and H. Liu, “Interplay of tumor vascular oxygenation and tumor pO2 observed using NIRS, pO2 needle electrode and 19F MR pO2 mapping,” J. Biomed. Opt. 8, 53-62 (2003).
    [Crossref]
  12. Y. Gu, V. A. Bourke, J. G. Kim, A. Constantinescu, R. P. Mason, and H. Liu, “Dynamic response of breast tumor oxygenation to hyperoxic respiratory challenges monitored with three oxygen-sensitive parameters,” Appl. Opt. 42, 2960-2967 (2003).
    [Crossref]
  13. S. Lee, H. Jeong, M. Seong, and J. G. Kim, “Change of tumor vascular reactivity during tumor growth and post-chemotherapy observed by near-infrared spectroscopy,” J. Biomed. Opt. 22(12), 1-9 (2017).
  14. J. G. Kim and H. Liu, “Variation of haemoglobin extinction coefficients can cause errors in the determination of haemoglobin concentration measured by near-infrared spectroscopy,” Phys. Med. Biol. 52, 6295 (2007).
    [Crossref]
  15. J. G. Kim and H. Liu, “Investigation of biphasic tumor oxygen dynamics induced by hyperoxic gas intervention: A numerical study,” Opt. Express 13, 4465-4475 (2005).
    [Crossref]
  16. J. G. Kim and H. Liu, “Investigation of biphasic tumor oxygen dynamics induced by hyperoxic gas intervention: A dynamic phantom study,” Appl. Opt. 47(2), 242-252 (2008).
    [Crossref]

2017 (1)

S. Lee, H. Jeong, M. Seong, and J. G. Kim, “Change of tumor vascular reactivity during tumor growth and post-chemotherapy observed by near-infrared spectroscopy,” J. Biomed. Opt. 22(12), 1-9 (2017).

2008 (1)

2007 (1)

J. G. Kim and H. Liu, “Variation of haemoglobin extinction coefficients can cause errors in the determination of haemoglobin concentration measured by near-infrared spectroscopy,” Phys. Med. Biol. 52, 6295 (2007).
[Crossref]

2005 (1)

2003 (2)

Y. Gu, V. A. Bourke, J. G. Kim, A. Constantinescu, R. P. Mason, and H. Liu, “Dynamic response of breast tumor oxygenation to hyperoxic respiratory challenges monitored with three oxygen-sensitive parameters,” Appl. Opt. 42, 2960-2967 (2003).
[Crossref]

J. G. Kim, D. Zhao, Y. Song, A. Constantinescu, R. P. Mason, and H. Liu, “Interplay of tumor vascular oxygenation and tumor pO2 observed using NIRS, pO2 needle electrode and 19F MR pO2 mapping,” J. Biomed. Opt. 8, 53-62 (2003).
[Crossref]

2000 (1)

1998 (1)

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

1995 (1)

V. M. Laurence, R. Ward, I. F. Dennis, and N. M. Bleehen, “Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients,” Br. J. Cancer 72, 198-205 (1995).
[Crossref]

1993 (1)

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

1991 (2)

E. Kjellen, M. C. Joiner, J. M. Collier, H. Johns, and A. Rojas, “A theraperutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments,” Radiother. Oncol. 22, 81-91 (1991).
[Crossref]

J. D. Chapman, C. C. Stobbe, M. R. Arnfield, R. Santus, J. Lee, and M. S. McPhee, “Oxygen dependency of tumor cell killing in vitro by light activated photofrin II,” Radiat. Res. 126, 73-79 (1991).
[Crossref]

1990 (1)

R. J. Whittle, A. P. Fuller, and R. R. Foley, “Glottic cancer: results of treatment with radiotherapy in air and hyperbaric oxygen,” Clin. Oncol. 2, 214-219 (1990)
[Crossref]

1987 (1)

J. W. Denham, E. K. Yeoh, G. Wittwer, G. G. Ward, A. S. Ahmad, and N. D. Harvey, “Radiation therapy in hyperbaric oxygen for head and neck cancer at Royal Adelaide Hospital-1964 to 1980,” Int. J. Radiat. Oncol., Biol., Phys. 13, 201-208 (1987).

1981 (1)

B. Teicher, J. Lazo, and A. Sartorelli, “Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells,” Cancer Res. 41, 73-81 (1981).

1955 (1)

R. H. Thomlinson and L. H. Gray, “The histological strucutre of some human lung cancers and the possible implications for radiotherapy,” Br. J. Cancer 9, 539-549 (1955).
[Crossref]

Ahmad, A. S.

J. W. Denham, E. K. Yeoh, G. Wittwer, G. G. Ward, A. S. Ahmad, and N. D. Harvey, “Radiation therapy in hyperbaric oxygen for head and neck cancer at Royal Adelaide Hospital-1964 to 1980,” Int. J. Radiat. Oncol., Biol., Phys. 13, 201-208 (1987).

Arnfield, M. R.

J. D. Chapman, C. C. Stobbe, M. R. Arnfield, R. Santus, J. Lee, and M. S. McPhee, “Oxygen dependency of tumor cell killing in vitro by light activated photofrin II,” Radiat. Res. 126, 73-79 (1991).
[Crossref]

Bleehen, N. M.

V. M. Laurence, R. Ward, I. F. Dennis, and N. M. Bleehen, “Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients,” Br. J. Cancer 72, 198-205 (1995).
[Crossref]

Bourke, V. A.

Chapman, J. D.

J. D. Chapman, C. C. Stobbe, M. R. Arnfield, R. Santus, J. Lee, and M. S. McPhee, “Oxygen dependency of tumor cell killing in vitro by light activated photofrin II,” Radiat. Res. 126, 73-79 (1991).
[Crossref]

Chapman, W.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Collier, J. M.

E. Kjellen, M. C. Joiner, J. M. Collier, H. Johns, and A. Rojas, “A theraperutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments,” Radiother. Oncol. 22, 81-91 (1991).
[Crossref]

Constantinescu, A.

Denham, J. W.

J. W. Denham, E. K. Yeoh, G. Wittwer, G. G. Ward, A. S. Ahmad, and N. D. Harvey, “Radiation therapy in hyperbaric oxygen for head and neck cancer at Royal Adelaide Hospital-1964 to 1980,” Int. J. Radiat. Oncol., Biol., Phys. 13, 201-208 (1987).

Dennis, I. F.

V. M. Laurence, R. Ward, I. F. Dennis, and N. M. Bleehen, “Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients,” Br. J. Cancer 72, 198-205 (1995).
[Crossref]

Eschwege, F.

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

Foley, R. R.

R. J. Whittle, A. P. Fuller, and R. R. Foley, “Glottic cancer: results of treatment with radiotherapy in air and hyperbaric oxygen,” Clin. Oncol. 2, 214-219 (1990)
[Crossref]

Fuller, A. P.

R. J. Whittle, A. P. Fuller, and R. R. Foley, “Glottic cancer: results of treatment with radiotherapy in air and hyperbaric oxygen,” Clin. Oncol. 2, 214-219 (1990)
[Crossref]

Fyles, A. W.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Gray, L. H.

R. H. Thomlinson and L. H. Gray, “The histological strucutre of some human lung cancers and the possible implications for radiotherapy,” Br. J. Cancer 9, 539-549 (1955).
[Crossref]

Gu, Y.

Guichard, M.

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

Harvey, N. D.

J. W. Denham, E. K. Yeoh, G. Wittwer, G. G. Ward, A. S. Ahmad, and N. D. Harvey, “Radiation therapy in hyperbaric oxygen for head and neck cancer at Royal Adelaide Hospital-1964 to 1980,” Int. J. Radiat. Oncol., Biol., Phys. 13, 201-208 (1987).

Hill, R. P.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Jeong, H.

S. Lee, H. Jeong, M. Seong, and J. G. Kim, “Change of tumor vascular reactivity during tumor growth and post-chemotherapy observed by near-infrared spectroscopy,” J. Biomed. Opt. 22(12), 1-9 (2017).

Jiang, X.

Johns, H.

E. Kjellen, M. C. Joiner, J. M. Collier, H. Johns, and A. Rojas, “A theraperutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments,” Radiother. Oncol. 22, 81-91 (1991).
[Crossref]

Joiner, M. C.

E. Kjellen, M. C. Joiner, J. M. Collier, H. Johns, and A. Rojas, “A theraperutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments,” Radiother. Oncol. 22, 81-91 (1991).
[Crossref]

Kavanagh, M. C.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Keane, T. J.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Kim, J. G.

S. Lee, H. Jeong, M. Seong, and J. G. Kim, “Change of tumor vascular reactivity during tumor growth and post-chemotherapy observed by near-infrared spectroscopy,” J. Biomed. Opt. 22(12), 1-9 (2017).

J. G. Kim and H. Liu, “Investigation of biphasic tumor oxygen dynamics induced by hyperoxic gas intervention: A dynamic phantom study,” Appl. Opt. 47(2), 242-252 (2008).
[Crossref]

J. G. Kim and H. Liu, “Variation of haemoglobin extinction coefficients can cause errors in the determination of haemoglobin concentration measured by near-infrared spectroscopy,” Phys. Med. Biol. 52, 6295 (2007).
[Crossref]

J. G. Kim and H. Liu, “Investigation of biphasic tumor oxygen dynamics induced by hyperoxic gas intervention: A numerical study,” Opt. Express 13, 4465-4475 (2005).
[Crossref]

Y. Gu, V. A. Bourke, J. G. Kim, A. Constantinescu, R. P. Mason, and H. Liu, “Dynamic response of breast tumor oxygenation to hyperoxic respiratory challenges monitored with three oxygen-sensitive parameters,” Appl. Opt. 42, 2960-2967 (2003).
[Crossref]

J. G. Kim, D. Zhao, Y. Song, A. Constantinescu, R. P. Mason, and H. Liu, “Interplay of tumor vascular oxygenation and tumor pO2 observed using NIRS, pO2 needle electrode and 19F MR pO2 mapping,” J. Biomed. Opt. 8, 53-62 (2003).
[Crossref]

Kjellen, E.

E. Kjellen, M. C. Joiner, J. M. Collier, H. Johns, and A. Rojas, “A theraperutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments,” Radiother. Oncol. 22, 81-91 (1991).
[Crossref]

Lambin, P.

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

Lartigau, E.

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

Laurence, V. M.

V. M. Laurence, R. Ward, I. F. Dennis, and N. M. Bleehen, “Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients,” Br. J. Cancer 72, 198-205 (1995).
[Crossref]

Lazo, J.

B. Teicher, J. Lazo, and A. Sartorelli, “Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells,” Cancer Res. 41, 73-81 (1981).

Le Ridant, A. M.

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

Lee, J.

J. D. Chapman, C. C. Stobbe, M. R. Arnfield, R. Santus, J. Lee, and M. S. McPhee, “Oxygen dependency of tumor cell killing in vitro by light activated photofrin II,” Radiat. Res. 126, 73-79 (1991).
[Crossref]

Lee, S.

S. Lee, H. Jeong, M. Seong, and J. G. Kim, “Change of tumor vascular reactivity during tumor growth and post-chemotherapy observed by near-infrared spectroscopy,” J. Biomed. Opt. 22(12), 1-9 (2017).

Levin, W.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Liu, H.

Luboinski, B.

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

Lusinchi, A.

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

Manchul, L.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Martin, L.

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

Mason, R. P.

McPhee, M. S.

J. D. Chapman, C. C. Stobbe, M. R. Arnfield, R. Santus, J. Lee, and M. S. McPhee, “Oxygen dependency of tumor cell killing in vitro by light activated photofrin II,” Radiat. Res. 126, 73-79 (1991).
[Crossref]

Milosevic, M.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Pintile, M.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Rojas, A.

E. Kjellen, M. C. Joiner, J. M. Collier, H. Johns, and A. Rojas, “A theraperutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments,” Radiother. Oncol. 22, 81-91 (1991).
[Crossref]

Santus, R.

J. D. Chapman, C. C. Stobbe, M. R. Arnfield, R. Santus, J. Lee, and M. S. McPhee, “Oxygen dependency of tumor cell killing in vitro by light activated photofrin II,” Radiat. Res. 126, 73-79 (1991).
[Crossref]

Sartorelli, A.

B. Teicher, J. Lazo, and A. Sartorelli, “Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells,” Cancer Res. 41, 73-81 (1981).

Seong, M.

S. Lee, H. Jeong, M. Seong, and J. G. Kim, “Change of tumor vascular reactivity during tumor growth and post-chemotherapy observed by near-infrared spectroscopy,” J. Biomed. Opt. 22(12), 1-9 (2017).

Song, Y.

J. G. Kim, D. Zhao, Y. Song, A. Constantinescu, R. P. Mason, and H. Liu, “Interplay of tumor vascular oxygenation and tumor pO2 observed using NIRS, pO2 needle electrode and 19F MR pO2 mapping,” J. Biomed. Opt. 8, 53-62 (2003).
[Crossref]

H. Liu, Y. Song, K. L. Worden, X. Jiang, A. Constantinescu, and R. P. Mason, “Noninvasive investigation of blood oxygenation dynamics of tumors by near-infrared spectroscopy,” Appl. Opt. 39, 5231-5243 (2000).
[Crossref]

Stobbe, C. C.

J. D. Chapman, C. C. Stobbe, M. R. Arnfield, R. Santus, J. Lee, and M. S. McPhee, “Oxygen dependency of tumor cell killing in vitro by light activated photofrin II,” Radiat. Res. 126, 73-79 (1991).
[Crossref]

Sun, A.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Teicher, B.

B. Teicher, J. Lazo, and A. Sartorelli, “Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells,” Cancer Res. 41, 73-81 (1981).

Thomlinson, R. H.

R. H. Thomlinson and L. H. Gray, “The histological strucutre of some human lung cancers and the possible implications for radiotherapy,” Br. J. Cancer 9, 539-549 (1955).
[Crossref]

Ward, G. G.

J. W. Denham, E. K. Yeoh, G. Wittwer, G. G. Ward, A. S. Ahmad, and N. D. Harvey, “Radiation therapy in hyperbaric oxygen for head and neck cancer at Royal Adelaide Hospital-1964 to 1980,” Int. J. Radiat. Oncol., Biol., Phys. 13, 201-208 (1987).

Ward, R.

V. M. Laurence, R. Ward, I. F. Dennis, and N. M. Bleehen, “Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients,” Br. J. Cancer 72, 198-205 (1995).
[Crossref]

Weeger, P.

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

Whittle, R. J.

R. J. Whittle, A. P. Fuller, and R. R. Foley, “Glottic cancer: results of treatment with radiotherapy in air and hyperbaric oxygen,” Clin. Oncol. 2, 214-219 (1990)
[Crossref]

Wibault, P.

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

Wittwer, G.

J. W. Denham, E. K. Yeoh, G. Wittwer, G. G. Ward, A. S. Ahmad, and N. D. Harvey, “Radiation therapy in hyperbaric oxygen for head and neck cancer at Royal Adelaide Hospital-1964 to 1980,” Int. J. Radiat. Oncol., Biol., Phys. 13, 201-208 (1987).

Wng, R.

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Worden, K. L.

Yeoh, E. K.

J. W. Denham, E. K. Yeoh, G. Wittwer, G. G. Ward, A. S. Ahmad, and N. D. Harvey, “Radiation therapy in hyperbaric oxygen for head and neck cancer at Royal Adelaide Hospital-1964 to 1980,” Int. J. Radiat. Oncol., Biol., Phys. 13, 201-208 (1987).

Zhao, D.

J. G. Kim, D. Zhao, Y. Song, A. Constantinescu, R. P. Mason, and H. Liu, “Interplay of tumor vascular oxygenation and tumor pO2 observed using NIRS, pO2 needle electrode and 19F MR pO2 mapping,” J. Biomed. Opt. 8, 53-62 (2003).
[Crossref]

Appl. Opt. (3)

Br. J. Cancer (2)

R. H. Thomlinson and L. H. Gray, “The histological strucutre of some human lung cancers and the possible implications for radiotherapy,” Br. J. Cancer 9, 539-549 (1955).
[Crossref]

V. M. Laurence, R. Ward, I. F. Dennis, and N. M. Bleehen, “Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients,” Br. J. Cancer 72, 198-205 (1995).
[Crossref]

Cancer Res. (1)

B. Teicher, J. Lazo, and A. Sartorelli, “Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells,” Cancer Res. 41, 73-81 (1981).

Clin. Oncol. (1)

R. J. Whittle, A. P. Fuller, and R. R. Foley, “Glottic cancer: results of treatment with radiotherapy in air and hyperbaric oxygen,” Clin. Oncol. 2, 214-219 (1990)
[Crossref]

Int. J. Radiat. Oncol., Biol., Phys. (1)

J. W. Denham, E. K. Yeoh, G. Wittwer, G. G. Ward, A. S. Ahmad, and N. D. Harvey, “Radiation therapy in hyperbaric oxygen for head and neck cancer at Royal Adelaide Hospital-1964 to 1980,” Int. J. Radiat. Oncol., Biol., Phys. 13, 201-208 (1987).

J. Biomed. Opt. (2)

S. Lee, H. Jeong, M. Seong, and J. G. Kim, “Change of tumor vascular reactivity during tumor growth and post-chemotherapy observed by near-infrared spectroscopy,” J. Biomed. Opt. 22(12), 1-9 (2017).

J. G. Kim, D. Zhao, Y. Song, A. Constantinescu, R. P. Mason, and H. Liu, “Interplay of tumor vascular oxygenation and tumor pO2 observed using NIRS, pO2 needle electrode and 19F MR pO2 mapping,” J. Biomed. Opt. 8, 53-62 (2003).
[Crossref]

Opt. Express (1)

Phys. Med. Biol. (1)

J. G. Kim and H. Liu, “Variation of haemoglobin extinction coefficients can cause errors in the determination of haemoglobin concentration measured by near-infrared spectroscopy,” Phys. Med. Biol. 52, 6295 (2007).
[Crossref]

Radiat. Res. (1)

J. D. Chapman, C. C. Stobbe, M. R. Arnfield, R. Santus, J. Lee, and M. S. McPhee, “Oxygen dependency of tumor cell killing in vitro by light activated photofrin II,” Radiat. Res. 126, 73-79 (1991).
[Crossref]

Radiother. Oncol. (3)

E. Kjellen, M. C. Joiner, J. M. Collier, H. Johns, and A. Rojas, “A theraperutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments,” Radiother. Oncol. 22, 81-91 (1991).
[Crossref]

L. Martin, E. Lartigau, P. Weeger, P. Lambin, A. M. Le Ridant, A. Lusinchi, P. Wibault, F. Eschwege, B. Luboinski, and M. Guichard, “Changes in the oxygenation of heat and neck tumors during carbogen breathing,” Radiother. Oncol. 27, 123-130 (1993).
[Crossref]

A. W. Fyles, M. Milosevic, R. Wng, M. C. Kavanagh, M. Pintile, A. Sun, W. Chapman, W. Levin, L. Manchul, T. J. Keane, and R. P. Hill, “Oxygenation predicts radiation response and survival in patients with cervix cancer,” Radiother. Oncol. 48(2), 149-156 (1998).
[Crossref]

Cited By

OSA participates in Crossref's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.