Generative optical modeling of whole blood for detecting platelets in lens-free images

Benjamin D. Haeffele, Christian Pick, Ziduo Lin, Evelien Mathieu, Stuart C. Ray, and René Vidal

Biomed. Opt. Express 11(4), 1808-1818 (2020)  View: HTML | PDF

Frugal filtering optical lenses for point-of-care diagnostics

Joanna Long, Helen E. Parker, Katjana Ehrlich, Michael G. Tanner, Kevin Dhaliwal, and Bethany Mills

Biomed. Opt. Express 11(4), 1864-1875 (2020)  View: HTML | PDF

Visualization of blood cell contrast in nailfold capillaries with high-speed reverse lens mobile phone microscopy

Gregory N. McKay, Nela Mohan, Ian Butterworth, Aurélien Bourquard, Álvaro Sánchez-Ferro, Carlos Castro-González, and Nicholas J. Durr

Biomed. Opt. Express 11(4), 2268-2276 (2020)  View: HTML | PDF  [Suppl. Mat. (2)]

Detail-preserving pulse wave extraction from facial videos using consumer-level camera

Dingliang Wang, Xuezhi Yang, Xuenan Liu, Jin Jing, and Shuai Fang

Biomed. Opt. Express 11(4), 1876-1891 (2020)  View: HTML | PDF

Prefrontal functional connectivity analysis of cognitive decline for early diagnosis of mild cognitive impairment: a functional near-infrared spectroscopy study

Jin-Woo Yu, Sung-Ho Lim, Bomin Kim, Eunho Kim, Kyungsoo Kim, Sung Kyu Park, Young Seok Byun, Joon Sakong, and Ji-Woong Choi

Biomed. Opt. Express 11(4), 1725-1741 (2020)  View: HTML | PDF

Concepts for structured illumination microscopy with extended axial resolution through mirrored illumination

James D. Manton, Florian Ströhl, Reto Fiolka, Clemens F. Kaminski, and Eric J. Rees

Biomed. Opt. Express 11(4), 2098-2108 (2020)  View: HTML | PDF  [Suppl. Mat. (4)]

Label-free optical imaging in developmental biology [Invited]

Shang Wang, Irina V. Larina, and Kirill V. Larin

Biomed. Opt. Express 11(4), 2017-2040 (2020)  View: HTML | PDF

Large-scale label-free single-cell analysis of paramylon in Euglena gracilis by high-throughput broadband Raman flow cytometry

Kotaro Hiramatsu, Koji Yamada, Matthew Lindley, Kengo Suzuki, and Keisuke Goda

Biomed. Opt. Express 11(4), 1752-1759 (2020)  View: HTML | PDF

Polarimetric second-harmonic generation microscopy of the hierarchical structure of collagen in stage I-III non-small cell lung carcinoma

Ahmad Golaraei, Leila B. Mostaço-Guidolin, Vaishnavi Raja, Roya Navab, Tao Wang, Shingo Sakashita, Kazuhiro Yasufuku, Ming-Sound Tsao, Brian C. Wilson, and Virginijus Barzda

Biomed. Opt. Express 11(4), 1851-1863 (2020)  View: HTML | PDF

Optical diffraction tomography with finite object support for the minimization of missing cone artifacts

Wojciech Krauze

Biomed. Opt. Express 11(4), 1919-1926 (2020)  View: HTML | PDF

Metasurface-based total internal reflection microscopy

Antu Nehuen Gortari, Sophie Bouchoule, Edmond Cambril, Andrea Cattoni, Lara Hauke, Jörg Enderlein, Florian Rehfeldt, and Alejandro Yacomotti

Biomed. Opt. Express 11(4), 1967-1976 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Polarization contrast optical diffraction tomography

Jos van Rooij and Jeroen Kalkman

Biomed. Opt. Express 11(4), 2109-2121 (2020)  View: HTML | PDF

Platform for quantitative multiscale imaging of tissue composition

Michael A. Pinkert, Zachary J. Simmons, Ryan C. Niemeier, Bing Dai, Lauren B. Woods, Timothy J. Hall, Paul J. Campagnola, Jeremy D. Rogers, and Kevin W. Eliceiri

Biomed. Opt. Express 11(4), 1927-1946 (2020)  View: HTML | PDF

Multimodal quantitative optical elastography of the crystalline lens with optical coherence elastography and Brillouin microscopy

Yogeshwari S. Ambekar, Manmohan Singh, Jitao Zhang, Achuth Nair, Salavat R. Aglyamov, Giuliano Scarcelli, and Kirill V. Larin

Biomed. Opt. Express 11(4), 2041-2051 (2020)  View: HTML | PDF

Functional optical coherence tomography and photoacoustic microscopy imaging for zebrafish larvae

Richard Haindl, Abigail J. Deloria, Caterina Sturtzel, Harald Sattmann, Wolfgang Rohringer, Balthasar Fischer, Marco Andreana, Angelika Unterhuber, Thorsten Schwerte, Martin Distel, Wolfgang Drexler, Rainer Leitgeb, and Mengyang Liu

Biomed. Opt. Express 11(4), 2137-2151 (2020)  View: HTML | PDF

Thermal damage threshold of neurons during infrared stimulation

William G. A. Brown, Karina Needham, James M. Begeng, Alexander C. Thompson, Bryony A. Nayagam, Tatiana Kameneva, and Paul R. Stoddart

Biomed. Opt. Express 11(4), 2224-2234 (2020)  View: HTML | PDF

Development and clinical trial of a smartphone-based colorimetric detection system for self-monitoring of blood glucose

Hung-Chih Wang, Fuh-Yu Chang, Tung-Meng Tsai, Chieh-Hsiao Chen, and Yen-Yu Chen

Biomed. Opt. Express 11(4), 2166-2177 (2020)  View: HTML | PDF

Realization of a time-correlated photon counting technique for fluorescence analysis

Lei Dai, Jian Liu, Kun Liang, Ru Yang, Dejun Han, and Bo Lu

Biomed. Opt. Express 11(4), 2205-2212 (2020)  View: HTML | PDF

Phase unwrapping based on a residual en-decoder network for phase images in Fourier domain Doppler optical coherence tomography

Chuanchao Wu, Zhengyu Qiao, Nan Zhang, Xiaochen Li, Jingfan Fan, Hong Song, Danni Ai, Jian Yang, and Yong Huang

Biomed. Opt. Express 11(4), 1760-1771 (2020)  View: HTML | PDF

Analysis of longitudinal sections of retinal vessels using Doppler OCT

Sylvia Desissaire, Florian Schwarzhans, Matthias Salas, Andreas Wartak, Georg Fischer, Clemens Vass, Michael Pircher, and Christoph K. Hitzenberger

Biomed. Opt. Express 11(4), 1772-1789 (2020)  View: HTML | PDF  [Suppl. Mat. (2)]

Automated morphometric measurement of the retinal pigment epithelium complex and choriocapillaris using swept source OCT

Hao Zhou, Yining Dai, Giovanni Gregori, Philip R. Rosenfeld, Jacque L. Duncan, Daniel M. Schwartz, and Ruikang K. Wang

Biomed. Opt. Express 11(4), 1834-1850 (2020)  View: HTML | PDF

Forward multiple scattering dominates speckle decorrelation in whole-blood flowmetry using optical coherence tomography

Natalie G. Ferris, Taylor M. Cannon, Martin Villiger, Brett E. Bouma, and Néstor Uribe-Patarroyo

Biomed. Opt. Express 11(4), 1947-1966 (2020)  View: HTML | PDF

Three-dimensional visualization of opacifications in the murine crystalline lens by in vivo optical coherence tomography

Pablo Eugui, Danielle J. Harper, Stefan Kummer, Antonia Lichtenegger, Johanna Gesperger, Tanja Himmel, Marco Augustin, Conrad W. Merkle, Martin Glösmann, and Bernhard Baumann

Biomed. Opt. Express 11(4), 2085-2097 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Discriminating different grades of cervical intraepithelial neoplasia based on label-free phasor fluorescence lifetime imaging microscopy

Xinyi Wang, Yulan Wang, Zixiao Zhang, Maojia Huang, Yiyan Fei, Jiong Ma, and Lan Mi

Biomed. Opt. Express 11(4), 1977-1990 (2020)  View: HTML | PDF

Hyperspectral evaluation of peritoneal fibrosis in mouse models

Jošt Stergar, Rok Dolenec, Nika Kojc, Katja Lakota, Martina Perše, Matija Tomšič, and Matija Milanic

Biomed. Opt. Express 11(4), 1991-2006 (2020)  View: HTML | PDF

Spectroscopic properties of various blood antigens/antibodies

Seyedeh Solaleh Seyedi, Parviz Parvin, Amir Jafargholi, Nazanin Hashemi, Seyed Morteza Tabatabaee, Ali Abbasian, and Ahmad Khorrami

Biomed. Opt. Express 11(4), 2298-2312 (2020)  View: HTML | PDF

Combined Nd:YAG and Er:YAG lasers for real-time closed-loop tissue-specific laser osteotomy

Hamed Abbasi, Lina M. Beltrán Bernal, Arsham Hamidi, Antoine Droneau, Ferda Canbaz, Raphael Guzman, Steven L. Jacques, Philippe C. Cattin, and Azhar Zam

Biomed. Opt. Express 11(4), 1790-1807 (2020)  View: HTML | PDF

Automatic protocol for quantifying the vasoconstriction in blood vessel images

Xuelin Xu, Lisheng Lin, and Buhong Li

Biomed. Opt. Express 11(4), 2122-2136 (2020)  View: HTML | PDF

Corneal hydration assessment indicator based on terahertz time domain spectroscopy

Jiali Yao, Jiaonan Ma, Jiehui Zhao, Pengfei Qi, Mengdi Li, Lie Lin, Lu Sun, Xiaolei Wang, Weiwei Liu, and Yan Wang

Biomed. Opt. Express 11(4), 2073-2084 (2020)  View: HTML | PDF

Terahertz three-dimensional monitoring of nanoparticle-assisted laser tissue soldering

Junliang Dong, Holger Breitenborn, Riccardo Piccoli, Lucas V. Besteiro, Pei You, Diego Caraffini, Zhiming M. Wang, Alexander O. Govorov, Rafik Naccache, Fiorenzo Vetrone, Luca Razzari, and Roberto Morandotti

Biomed. Opt. Express 11(4), 2254-2267 (2020)  View: HTML | PDF

The Valsalva maneuver: an indispensable physiological tool to differentiate intra versus extracranial near-infrared signal

David James Davies, Kamal Makram Yakoub, Zhangjie Su, Michael Clancy, Mario Forcione, Samuel John Edwin Lucas, Hamid Dehghani, and Antonio Belli

Biomed. Opt. Express 11(4), 1712-1724 (2020)  View: HTML | PDF

Laser fluorescence spectroscopy in predicting the formation of a keloid scar: preliminary results and the role of lipopigments

Andreeva Viktoriya, Raznitsyna Irina, Gerzhik Anastasiia, Glazkov Alexey, Makmatov-Rys Mikhail, Birlova Eleonora, Chursinova Yuliya, Bobrov Maksim, Rogatkin Dmitry, Sipkin Aleksandr, and Kulikov Dmitry

Biomed. Opt. Express 11(4), 1742-1751 (2020)  View: HTML | PDF

Study on the chemodrug-induced effect in nasopharyngeal carcinoma cells using laser tweezer Raman spectroscopy

Sufang Qiu, Miaomiao Li, Jun Liu, Xiaochuan Chen, Ting Lin, Yunchao Xu, Yang Chen, Youliang Weng, Yuhui Pan, Shangyuan Feng, Xiandong Lin, Lurong Zhang, and Duo Lin

Biomed. Opt. Express 11(4), 1819-1833 (2020)  View: HTML | PDF

Determination of refractive index, size, and solid content of monodisperse polystyrene microsphere suspensions for the characterization of optical phantoms

Peter Naglič, Yevhen Zelinskyi, Boštjan Likar, and Miran Bürmen

Biomed. Opt. Express 11(4), 1901-1918 (2020)  View: HTML | PDF

Multifunctional laser speckle imaging

E. Du, Shuhao Shen, Shau Poh Chong, and Nanguang Chen

Biomed. Opt. Express 11(4), 2007-2016 (2020)  View: HTML | PDF  [Suppl. Mat. (1)]

Wide-field optical spectroscopy system integrating reflectance and spatial frequency domain imaging to measure attenuation-corrected intrinsic tissue fluorescence in radical prostatectomy specimens

Emile Beaulieu, Audrey Laurence, Mirela Birlea, Guillaume Sheehy, Leticia Angulo-Rodriguez, Mathieu Latour, Roula Albadine, Fred Saad, Dominique Trudel, and Frédéric Leblond

Biomed. Opt. Express 11(4), 2052-2072 (2020)  View: HTML | PDF

Spectral clustering-based resting-state network detection approach for functional near-infrared spectroscopy

Lian Duan and Xiaoqin Mai

Biomed. Opt. Express 11(4), 2191-2204 (2020)  View: HTML | PDF

Measuring cell displacements in opaque tissues: dynamic light scattering in the multiple scattering regime

Benjamin Brunel, Vincent Levy, Arnaud Millet, Monika Elzbieta Dolega, Antoine Delon, Romain Pierrat, and Giovanni Cappello

Biomed. Opt. Express 11(4), 2277-2297 (2020)  View: HTML | PDF

Peripheral image quality in pseudophakic eyes

Konstantina A. Togka, Angelos Livir-Rallatos, Dimitrios Christaras, Spyridon Tsoukalas, Nikolaos Papasyfakis, Pablo Artal, and Harilaos Ginis

Biomed. Opt. Express 11(4), 1892-1900 (2020)  View: HTML | PDF

High resolution 3D visualization of the spinal cord in a post-mortem murine model

Inna Bukreeva, Victor Asadchikov, Alexey Buzmakov, Marina Chukalina, Anastasya Ingacheva, Nikolay A. Korolev, Alberto Bravin, Alberto Mittone, Gabriele E. M. Biella, Alejandra Sierra, Francesco Brun, Lorenzo Massimi, Michela Fratini, and Alessia Cedola

Biomed. Opt. Express 11(4), 2235-2253 (2020)  View: HTML | PDF