Recent progress in optical probing and manipulation of tissue: introduction

Kirill V. Larin, Dan Zhu, Alexander Priezzhev, and David D. Sampson

Biomed. Opt. Express 10(10), 5159-5161 (2019)  View: HTML | PDF

Concurrent fluorescence and volumetric optoacoustic tomography of nanoagent perfusion and bio-distribution in solid tumors

Zhenyue Chen, Xosé Luis Deán-Ben, Nian Liu, Vipul Gujrati, Sven Gottschalk, Vasilis Ntziachristos, and Daniel Razansky

Biomed. Opt. Express 10(10), 5093-5102 (2019)  View: HTML | PDF

In-vivo and ex-vivo optical clearing methods for biological tissues: review

Irene Costantini, Riccardo Cicchi, Ludovico Silvestri, Francesco Vanzi, and Francesco Saverio Pavone

Biomed. Opt. Express 10(10), 5251-5267 (2019)  View: HTML | PDF  [Suppl. Mat. (1)]

Ptychographic imaging of NaD1 induced yeast cell death

Nicholas Anthony, Connie Darmanin, Mark R Bleackley, Kathy Parisi, Guido Cadenazzi, Susannah Holmes, Marilyn A Anderson, Keith A Nugent, and Brian Abbey

Biomed. Opt. Express 10(10), 4964-4974 (2019)  View: HTML | PDF

Quantitative assessment of changes in cellular morphology at photodynamic treatment in vitro by means of digital holographic microscopy

A. V. Belashov, A. A. Zhikhoreva, T. N. Belyaeva, N. N. Nikolsky, I. V. Semenova, E. S. Kornilova, and O. S. Vasyutinskii

Biomed. Opt. Express 10(10), 4975-4986 (2019)  View: HTML | PDF

Polar organization of collagen in human cardiac tissue revealed with polarimetric second-harmonic generation microscopy

Kamdin Mirsanaye, Ahmad Golaraei, Fayez Habach, Edvardas Žurauskas, Jonas Venius, Ricardas Rotomskis, and Virginijus Barzda

Biomed. Opt. Express 10(10), 5025-5030 (2019)  View: HTML | PDF

Aberration-free multi-plane imaging of neural activity from the mammalian brain using a fast-switching liquid crystal spatial light modulator

Rui Liu, Neil Ball, James Brockill, Leonard Kuan, Daniel Millman, Cassandra White, Arielle Leon, Derric Williams, Shig Nishiwaki, Saskia de Vries, Josh Larkin, David Sullivan, Cliff Slaughterbeck, Colin Farrell, and Peter Saggau

Biomed. Opt. Express 10(10), 5059-5080 (2019)  View: HTML | PDF  [Suppl. Mat. (4)]

Live imaging of contracting muscles with wide-field second harmonic generation microscopy using a high power laser

Haitao Zhao, Richard Cisek, Abiramy Karunendiran, Danielle Tokarz, Bryan A. Stewart, and Virginijus Barzda

Biomed. Opt. Express 10(10), 5130-5135 (2019)  View: HTML | PDF  [Suppl. Mat. (1)]

Stimulated Raman histology: one to one comparison with standard hematoxylin and eosin staining

Barbara Sarri, Flora Poizat, Sandro Heuke, Julien Wojak, Florence Franchi, Fabrice Caillol, Marc Giovannini, and Herve Rigneault

Biomed. Opt. Express 10(10), 5378-5384 (2019)  View: HTML | PDF

Ratiometric widefield imaging with spectrally balanced detection

Shimon Yudovich, Lior Shani, Asaf Grupi, Omri Bar-Elli, Dan Steinitz, Dan Oron, and Shimon Weiss

Biomed. Opt. Express 10(10), 5385-5394 (2019)  View: HTML | PDF

Simultaneous label-free autofluorescence and multi-harmonic imaging reveals in vivo structural and metabolic changes in murine skin

Jang Hyuk Lee, Jose J. Rico-Jimenez, Chi Zhang, Aneesh Alex, Eric J. Chaney, Ronit Barkalifa, Darold R. Spillman, Marina Marjanovic, Zane Arp, Steve R. Hood, and Stephen A. Boppart

Biomed. Opt. Express 10(10), 5431-5444 (2019)  View: HTML | PDF  [Suppl. Mat. (2)]

Visual method for evaluating liver function: targeted in vivo fluorescence imaging of the asialoglycoprotein receptor

Xiaojing Song, Shuyou Wang, Chong Zhao, Weibo Zhang, Guangjun Wang, and Shuyong Jia

Biomed. Opt. Express 10(10), 5015-5024 (2019)  View: HTML | PDF

Electric-field-assisted signal amplification for label-free liquid-crystal-based detection of biomolecules

Wei-Liang Hsu, Mon-Juan Lee, and Wei Lee

Biomed. Opt. Express 10(10), 4987-4998 (2019)  View: HTML | PDF

Label-free and specific detection of soluble programmed death ligand-1 using a localized surface plasmon resonance biosensor based on excessively tilted fiber gratings

Binbin Luo, Yajie Wang, Huafeng Lu, Shengxi Wu, Youming Lu, Shenghui Shi, Lingchen Li, Shanghai Jiang, and Mingfu Zhao

Biomed. Opt. Express 10(10), 5136-5148 (2019)  View: HTML | PDF

Deep learning based topology guaranteed surface and MME segmentation of multiple sclerosis subjects from retinal OCT

Yufan He, Aaron Carass, Yihao Liu, Bruno M. Jedynak, Sharon D. Solomon, Shiv Saidha, Peter A. Calabresi, and Jerry L. Prince

Biomed. Opt. Express 10(10), 5042-5058 (2019)  View: HTML | PDF

Polarization-sensitive optical coherence elastography

Arata Miyazawa, Shuichi Makita, En Li, Kohei Yamazaki, Masaki Kobayashi, Shingo Sakai, and Yoshiaki Yasuno

Biomed. Opt. Express 10(10), 5162-5181 (2019)  View: HTML | PDF  [Suppl. Mat. (2)]

Constrained polarization evolution simplifies depth-resolved retardation measurements with polarization-sensitive optical coherence tomography

Qiaozhou Xiong, Nanshuo Wang, Xinyu Liu, Si Chen, Cilwyn S. Braganza, Brett E. Bouma, Linbo Liu, and Martin Villiger

Biomed. Opt. Express 10(10), 5207-5222 (2019)  View: HTML | PDF

Longitudinal deep-brain imaging in mouse using visible-light optical coherence tomography through chronic microprism cranial window

Lisa Beckmann, Xian Zhang, Neil A. Nadkarni, Zhen Cai, Ayush Batra, David P. Sullivan, William A. Muller, Cheng Sun, Roman Kuranov, and Hao F. Zhang

Biomed. Opt. Express 10(10), 5235-5250 (2019)  View: HTML | PDF

Analysis and evaluation of BC-mode OCT image visualization for microsurgery guidance

Shuwen Wei, Shoujing Guo, and Jin U. Kang

Biomed. Opt. Express 10(10), 5268-5290 (2019)  View: HTML | PDF  [Suppl. Mat. (1)]

Accurate tissue interface segmentation via adversarial pre-segmentation of anterior segment OCT images

Jiahong Ouyang, Tejas Sudharshan Mathai, Kira Lathrop, and John Galeotti

Biomed. Opt. Express 10(10), 5291-5324 (2019)  View: HTML | PDF  [Suppl. Mat. (3)]

Automated accurate lumen segmentation using L-mode interpolation for three-dimensional intravascular optical coherence tomography

Arsalan Akbar, T. S. Khwaja, Ammar Javaid, Jun-sun Kim, and Jinyong Ha

Biomed. Opt. Express 10(10), 5325-5336 (2019)  View: HTML | PDF

Automated quantification of choriocapillaris anatomical features in ultrahigh-speed optical coherence tomography angiograms

Brennan Marsh-Armstrong, Justin Migacz, Ravi Jonnal, and John S. Werner

Biomed. Opt. Express 10(10), 5337-5350 (2019)  View: HTML | PDF  [Suppl. Mat. (1)]

Early diagnosis of gastric cancer based on deep learning combined with the spectral-spatial classification method

Yuanpeng Li, Liangyu Deng, Xinhao Yang, Zhao Liu, Xiaoping Zhao, Furong Huang, Siqi Zhu, Xingdan Chen, Zhenqiang Chen, and Weimin Zhang

Biomed. Opt. Express 10(10), 4999-5014 (2019)  View: HTML | PDF

Fluorescence modeling of in vivo optical detection of Mycobacterium tuberculosis

Madeleine S. Durkee, Jeffrey D. Cirillo, and Kristen C. Maitland

Biomed. Opt. Express 10(10), 5445-5460 (2019)  View: HTML | PDF

Enhanced photothermal hemostasis using dual wavelengths in an in vivo leporine kidney model

Sung won Kim, Jieun Hwang, Jason Xuan, Thomas Hasenberg, and Hyun Wook Kang

Biomed. Opt. Express 10(10), 5198-5206 (2019)  View: HTML | PDF

Differential detachment of intact and viable cells of different sizes using laser-induced microbubbles

Wanyoung Lim, Seungjin Lee, Sungsu Park, and Hyoung Won Baac

Biomed. Opt. Express 10(10), 4919-4930 (2019)  View: HTML | PDF

Effective demethylation of melanoma cells using terahertz radiation

Hwayeong Cheon, Hee-Jin Yang, Moran Choi, and Joo-Hiuk Son

Biomed. Opt. Express 10(10), 4931-4941 (2019)  View: HTML | PDF

Study of the dielectric characteristics of living glial-like cells using terahertz ATR spectroscopy

Yuye Wang, Zhinan Jiang, Degang Xu, Tunan Chen, Beike Chen, Shi Wang, Ning Mu, Hua Feng, and Jianquan Yao

Biomed. Opt. Express 10(10), 5351-5361 (2019)  View: HTML | PDF

Waveform analysis of human retinal and choroidal blood flow with laser Doppler holography

Léo Puyo, Michel Paques, Mathias Fink, José-Alain Sahel, and Michael Atlan

Biomed. Opt. Express 10(10), 4942-4963 (2019)  View: HTML | PDF  [Suppl. Mat. (5)]

Method to improve the depth sensitivity of diffuse reflectance measurements to absorption changes in optically turbid medium

Piotr Sawosz and Adam Liebert

Biomed. Opt. Express 10(10), 5031-5041 (2019)  View: HTML | PDF

Classification of diffuse light emission profiles for distinguishing skin layer penetration of a needle-free jet injection

Kieran A. Brennan, Bryan P. Ruddy, Poul M. F. Nielsen, and Andrew J. Taberner

Biomed. Opt. Express 10(10), 5081-5092 (2019)  View: HTML | PDF

Handheld motion stabilized laser speckle imaging

Ben Lertsakdadet, Cody Dunn, Adrian Bahani, Christian Crouzet, and Bernard Choi

Biomed. Opt. Express 10(10), 5149-5158 (2019)  View: HTML | PDF  [Suppl. Mat. (2)]

Optical properties of brain tissues at the different stages of glioma development in rats: pilot study

Elina A. Genina, Alexey N. Bashkatov, Daria K. Tuchina, Polina A. Dyachenko (Timoshina), Nikita Navolokin, Alexander Shirokov, Alexander Khorovodov, Andrey Terskov, Maria Klimova, Aysel Mamedova, Inna Blokhina, Ilana Agranovich, Ekaterina Zinchenko, Oxana V. Semyachkina-Glushkovskaya, and Valery V. Tuchin

Biomed. Opt. Express 10(10), 5182-5197 (2019)  View: HTML | PDF

Second harmonic generation imaging reveals asymmetry in the rotational helicity of collagen lamellae in chicken corneas

Sheng-Lin Lee, Yang-Fang Chen, and Chen-Yuan Dong

Biomed. Opt. Express 10(10), 5223-5234 (2019)  View: HTML | PDF

Small separation frequency-domain near-infrared spectroscopy for the recovery of tissue optical properties at millimeter depths

Seung Yup Lee, Corey Zheng, Rowan Brothers, and Erin M. Buckley

Biomed. Opt. Express 10(10), 5362-5377 (2019)  View: HTML | PDF

Recovery of the diffuse correlation spectroscopy data-type from speckle contrast measurements: towards low-cost, deep-tissue blood flow measurements

K. Murali, A. K. Nandakumaran, Turgut Durduran, and Hari M. Varma

Biomed. Opt. Express 10(10), 5395-5413 (2019)  View: HTML | PDF

High-resolution VSDI retinotopic mapping via a DLP-based projection system

Adi Gross, Nadav H. Ivzan, Nairouz Farah, and Yossi Mandel

Biomed. Opt. Express 10(10), 5117-5129 (2019)  View: HTML | PDF  [Suppl. Mat. (1)]