Abstract

Thermoacoustic (TA) imaging is a modality where pulsed microwaves are used to generate ultrasound waves in tissue, which are highly correlated with temperature. This study uses a self-calibration approach to improve the estimation of temperature using 3D real-time TA thermometry in porcine tissue during localized heating. The self-calibration method estimated temperatures at eight embedded thermocouple locations with a normalized root-mean-square error of ${3.25} \pm {2.08}\%$. The results demonstrate that the method has the suitable accuracy and resolution to provide feedback control for breast cancer ablation therapy.

© 2020 Optical Society of America

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