Add to BibSonomyAbstract
The development and bench testing of a fiber-optic oxygen sensor is described. The sensor is designed for measurement of tissue oxygen levels in the mucosa of the digestive tract. The materials and construction are optimized for insertion through the mouth for measurement in the lower esophagus. An oxygen-sensitive fluorescence-quenching film was applied as a solution of platinum octaethylporphyrin (PtOEP) poly(ethyl methacrylate) (PEMA) and dichloromethane and dip coated onto the distal tip of the fiber. The sensor was tested by comparing relative fluorescence when immersed in liquid water at 37°C, at a range of partial pressures (0–101 kPa). Maximum relative fluorescence at most oxygen concentrations was seen when the PtOEP concentration was , four layers of coating solution were applied, and a fiber core radius of 600 μm was selected, giving a Stern–Volmer constant of . The performance of the sensor is suitable for many in vivo applications, particularly mucosal measurements. It has sufficient sensitivity, is sterilizable, and is sufficiently flexible and robust for insertion via the mouth without damage to the probe or risk of harm to the patient.
© 2016 Optical Society of America
Full Article | PDF ArticleMore Like This
Fenghong Chu, Junjie Yang, Haiwen Cai, Ronghui Qu, and Zujie Fang
Appl. Opt. 48(2) 338-342 (2009)
Zhixuan Er, Ping Gong, Jian Zhou, Yiming Wang, Xiaokang Jiang, and Liang Xie
Appl. Opt. 61(16) 4865-4873 (2022)
M. E. Cox and B. Dunn
Appl. Opt. 24(14) 2114-2120 (1985)