Global cell features—Functions defined on the optical density range from 0 to 255 |
# SIGNUCS | Number of nuclear boundaries detected. |
CELLAREA | Total area of the entire object. |
CELLTEXT | Integrated optical density of the entire object. |
CELLAVER | Mean O.D. per pixel of the entire object. |
CELLSTND | Standard deviation of O.D. per pixel of the entire object. |
CELLSKEW | Skewness of O.D. per pixel of the entire object. |
CELLKURT | Kurtosis of the O.D. per pixel of the entire object. |
CELLMAXM | Maximum O.D. in the object. |
NUCTHRSH | Nuclear threshold O.D. |
NUCLAREA | Area enclosed by all nuclear boundaries. |
NUCAVEXT | Mean O.D. per pixel for all nuclei. |
NUCSTEXT | Standard deviation of O.D. per pixel for all nuclei. |
NUCSKEXT | Skewness of O.D. per pixel for all nuclei. |
NUCKREXT | Kurtosis of O.D. per pixel for all nuclei. |
LENGPERM | Perimeter of the boundary of the largest nucleus (nuclear boundary). |
SEMIMAJR | Semimajor axis of the Fourier ellipse fitting the nuclear boundary. |
SEMIMINR | Semiminor axis of the Fourier ellipse fitting the nuclear boundary. |
ECCENTRC | Eccentricity of the Fourier ellipse fitting the nuclear boundary. |
#SIGCONC | Number of significant concavities on the nuclear boundary. |
AVBSECON | Mean base length of concavities on the nuclear boundary. |
AVDTHCON | Mean depth of concavities on the nuclear boundary. |
AVARECON | Mean area enclosed by concavities on the nuclear boundary. |
BSE/SMIN | Ratio of AVBSECON to SEMIMINR. |
DTH/SMIN | Ratio of AVDTHCON to SEMIMNR. |
ARE/SMIN | Ratio of AVARECON to SEMIMINR. |
AVGTHRSH | Mean O.D. per pixel along nuclear boundary. |
STDTHRSH | Standard deviation of O.D. per pixel along nuclear boundary. |
AVDIFBND | Mean O.D. difference between neighboring pixels on nuclear boundary. |
AVDFOUT1 | Mean O.D. difference between pixels on the nuclear boundary and their neighbors one pixel outward from boundary. |
AVDFOUT2 | Mean O.D. difference between pixels on the nuclear boundary and their neighbors two pixels outward from boundary. |
CYTAVDIF | Mean O.D. difference between nearest neighbors in the cytoplasm‥i -10;CYTDVDIF Standard deviation of O.D. difference between nearest neighbors in the cytoplasm. |
CYTSKDIF | Skewness of O.D. difference between nearest neighbors in the cytoplasm. |
CYTKUDIF | Kurtosis of O.D. difference between nearest neighbors in the cytoplasm. |
NUCAVDF1 | Mean O.D. difference between nearest neighbors in the nucleus. |
NUCDVDF1 | Standard deviation of O.D. difference between nearest neighbors in the nucleus. |
NUCSKDF1 | Skewness of O.D. difference between nearest neighbors in the nucleus. |
NUCKUDF1 | Kurtosis of O.D. difference between nearest neighbors in the nucleus. |
NUCAVDF2 | Mean O.D. difference between second nearest neighbors in the nucleus. |
NUCDVDF2 | Standard deviation of O.D. difference between second nearest neighbors in the nucleus. |
NUCSKDF2 | Skewness of O.D. difference between second nearest neighbors in the nucleus. |
NUCKUDF2 | Kurtosis of O.D. difference between second nearest neighbors in the nucleus. |
NAR/CELA | Ratio of NUCLAREA to CELLAREA. |
N**2/CEL | Ratio of the square of NUCLAREA to CELLAREA. |
Shrink features—Derived from compiling selected features above for trial nuclear thresholds over the range from NUCTHRSH and CELLMAXM. |
MX(A/P2) | Maximum compactness (NUCLAREA/LENGPERM2) of trial boundaries. |
AV(A/P2) | Mean compactness of trial boundaries. |
DV(A/P2) | Standard deviation of compactness of trial boundaries. |
SK(A/P2) | Skewness of compactness of trial boundaries. |
KR(A/P2) | Kurtosis of compactness of trial boundaries. |
AVG-AREA | Mean area enclosed by trial boundaries. |
STD-AREA | Standard deviation of area enclosed by trial boundaries. |
SKW-AREA | Skewness of area enclosed by trial boundaries. |
KUR-AREA | Kurtosis of area enclosed by trial boundaries. |
AVAVGEXT | Mean of NUCAVEXT of trial boundaries. |
STAVGEXT | Standard deviation of NUCAVEXT of trial boundaries. |
SKAVGEXT | Skewness of NUCAVEXT of trial boundaries. |
KRAVGEXT | Kurtosis of NUCAVEXT of trial boundaries. |
MAXDFOUT | Maximum AVDFOUT1 of trial boundaries. |
AVGDFOUT | Mean AVDTOUT1 of trial boundaries. |
STDDFOUT | Standard deviation of AVDFOUT1 of trial boundaries. |
SKWDFOUT | Skewness of AVDFOUT1 of trial boundaries. |
KURDFOUT | Kurtosis of AVDFOUT1 of trial boundaries. |
AV#NUCLI | Mean no. SIGNUCS of trial boundaries. |
SUMTOT#N | Sum of no. SIGNUCS of all trial boundaries. |