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High performance pathology workstation using an automated multispectral microscope

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Abstract

Modern evaluation of cytological and histological specimens utilizes multispectral microscopic observation of transmissively illuminated fields as well as fluorescence images to analyze specimens treated with cytochemical probes. A user-friendly, interactive, multispectral image-processing capability is, therefore, required to accommodate the needs of the practicing cytologist. This paper describes a system design for a high-speed, microscopic, multispectral image analysis that provides a natural user-friendly environment for the cytologist. The speed limitations of conventional image processors are overcome by employing multiple processors in a high-speed, highly parallel-pipelined architecture. Preliminary results obtained using a prototype system for interactive ploidy determination will be presented. Software now under development will address a broad range of quantitative cytology problems utilizing the system's capability to measure a wide variety of cytomorphic properties in apparent real time.

© 1987 Optical Society of America

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