Imaging of microvascular blood flow in the exposed cerebral cortex of a mouse was achieved by laser holographic interferometry with a 50 kHz framerate camera. Videos of local Doppler contrasts were rendered numerically by Fresnel transformation and short-time Fourier transform analysis of off-axis holograms. Pulsatile blood flow contrasts in superficial blood vessels were revealed with a spatial resolution of 10 microns and a temporal resolution of 20 ms.

© 2016 Optical Society of America

PDF Article


You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
Login to access OSA Member Subscription