Abstract

Given the complimentary contrast mechanisms of Photoacoustic microscopy (PAM) and Optical coherence tomography (OCT), the combination of PAM and OCT imaging could potentially provide much sensitive and specific detection of retinal diseases. We performed the dual-modality Optical coherence photoacoustic microscopy on Age related macular degeneration (AMD) model in rat to investigate the morphology and variability of the AMD disease and to validate the therapeutic approach. Images of Retinal/choroidal vessels and the RPE at a high contrast were given in PAM information and details of high axial resolution cross-sectional OCT images were simultaneously given to show the reflective reaction.

© 2017 Optical Society of America