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Flexible piezoeletric nanogenerators for in vivo applications

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Abstract

In-vivo devices and systems are extensively used in medical field to real-time detect and adjust the physiological status of human being, but supplying energy in-vivo for these devices and systems is still a great challenge. In this talk, we first systematically studied the in trivo and in vivo biocompatibility of lead-free 0.5Ba(Zr0.2Ti0.8)O3-0.5(Ba0.7Ca0.3)TiO3 (BZT-BCT) nanowires and the nanogenerator composed of them. We found the BZT-BCT nanowire NG has great potential to be applied as an in vivo power source. Then, we developed a new kind of wireless nanogenerator (WLNG) based on biocompatible BZT-BCT nanowires (NWs). It works through compressing and releasing BZT-BCT NWs/PDMS nanocomposite by a changing magnetic field in wireless non-contact mode. The maximum output voltage reaches 3.9 V, and the maximum output current is 1.17 μA, which are 21.9% larger than the reported maximum output voltage 3.2 V and 23.4 times of the reported maximum 50 nA of non-contact nanogenerator. And we further integrated it with a new kind of transmitter into a wireless, power-free and implantable nanosystem for in-vivo biodetection. This nanosystem doesn’t need any electrical power. An in-vitro changing magnetic field can be used to drive it to detect the variation of resistance in-vivo and wirelessly transmit the signal to the equipments in-vitro.

© 2015 Optical Society of America

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