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Improving penetration depth in biological imaging using Nd3+/Yb3+/Er3+-doped upconverting nanoparticles

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Abstract

We have synthesized and evaluated in tissue phantom measurements a new type of Nd-codoped upconverting nanoparticles. They provide improved signal strengths from deep regions in a tissue phantom as compared to conventional upconverting nanoparticles, a result also suggesting they will provide less issues with heating the tissue during measurements.

© 2016 Optical Society of America

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