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Untwisting and Unzipping: Magnetic Tweezers Based Measurements of DNA Processing Enzymes

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Abstract

Magnetic tweezers provide a versatile tool enabling the application of force and torque on individual DNA molecules. We have developed a high-resolution, actively-stabilized, magnetic tweezers to measure the activity of DNA topoisomerases and DNA helicases.

© 2015 Optical Society of America

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