Dynamic Biomolecule Sensing Bead Array Held by Optical Tweezers

Mael Manesse; Christopher N. Lafratta; Christopher N. Lafratta; Manuel A. Palacios; Aaron F. Phillips; David R. Walt

doi:10.1364/OTA.2011.OTTuC4

Optics in the Life Sciences
OSA Technical Digest (CD) (Optica Publishing Group, 2011),
paper OTTuC4
•https://doi.org/10.1364/OTA.2011.OTTuC4

Dynamic Biomolecule Sensing Bead Array Held by Optical Tweezers

Mael Manesse, Christopher N. Lafratta, Manuel A. Palacios, Aaron F. Phillips, and David R. Walt

Optical Trapping Applications 2011

Monterey, California United States
4–6 April 2011
ISBN: 978-1-55752-909-1

From the session
Trapping Techniques and Applications III (OTTuC)

Open Access

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M. Manesse, C. N. Lafratta, M. A. Palacios, A. F. Phillips, and D. R. Walt, "Dynamic Biomolecule Sensing Bead Array Held by Optical Tweezers," in Optics in the Life Sciences, OSA Technical Digest (CD) (Optica Publishing Group, 2011), paper OTTuC4.

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Abstract

We have developed a platform using optical tweezers to create dynamic arrays of functionalized microbeads in microfluidic channels. The array is then exposed to analyte signaling molecules and washes, and interrogated using fluorescence microscopy.

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