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Conferences > Microscopy > 2020 > MW4A > MW4A.5

Fluorescent Imaging for In Situ Measurement of Drug Target Engagement and Cell Signaling Pathways

Nathan McMahon, Allison Solanki, Jocelyn Jones, Sunjong Kwon, Young-Hwan Chang, Koei Chin, Michel Nederlof, Joe Gray, and Summer L. Gibbs

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Abstract

Successful targeted cancer treatment continues to elude modern medicine and its many therapeutic strategies. Herein, we propose a fluorescent imaging technique to measure drug localization and subsequent cell signaling perturbations on a single cell basis

© 2020 The Author(s)

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