Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group
Conferences > Microscopy > 2020 > MW1A > MW1A.1

Visualizing cancer pathogenesis at the nanoscale

Yang Liu, Hongqiang Ma, and Jianquan Xu

Not Accessible

Your library or personal account may give you access

Abstract

We present the technical development of a high-throughput super-resolution imaging system based on optimized stochastic optical reconstruction microscopy. This system enables robust and reliable super-resolution imaging of nanoscale chromatin folding over a large field of view on standard pathological tissue. Super-resolution microscopy revealed fragmented chromatin folding throughout all stages of carcinogenesis.

© 2020 The Author(s)

PDF Article  |   Presentation Video
More Like This
Super-resolution imaging of chromatin ultrastructure in cancer pathogenesis using small-molecule fluorescent probe

Jianquan Xu, Douglas Hartman, and Yang Liu
MTu2A.1 Microscopy Histopathology and Analytics (Microscopy) 2022

Nanoscale Imaging of Chromatin with Labeled and Label-Free Super-Resolution Microscopy and Partial-Wave Spectroscopy

Adam Eshein, Yue Li, Xiang Zhou, Graham Spicer, The-Quyen Nguyen, Luay M. Almassalha, John E. Chandler, Scott Gladstein, Biqin Dong, Cheng Sun, Hao F. Zhang, and Vadim Backman
MW2A.4 Microscopy Histopathology and Analytics (Microscopy) 2018

Imaging Nuclear Architecture at the Nanoscale for Cancer Detection and Prognosis

Yang Liu, Shikhar Uttam, Hoa V. Pham, Justin LaFace, and Douglas J. Hartman
OT1C.6 Bio-Optics: Design and Application (BODA) 2015

View More...

Presentation Video

Presentation video access is available to:

  1. Optica Publishing Group subscribers
  2. Technical meeting attendees
  3. Optica members who wish to use one of their free downloads. Please download the article first. After downloading, please refresh this page.

Contact your librarian or system administrator
or
Log in to access Optica Member Subscription or free downloads

More Like This
Super-resolution imaging of chromatin ultrastructure in cancer pathogenesis using small-molecule fluorescent probe

Jianquan Xu, Douglas Hartman, and Yang Liu
MTu2A.1 Microscopy Histopathology and Analytics (Microscopy) 2022

Nanoscale Imaging of Chromatin with Labeled and Label-Free Super-Resolution Microscopy and Partial-Wave Spectroscopy

Adam Eshein, Yue Li, Xiang Zhou, Graham Spicer, The-Quyen Nguyen, Luay M. Almassalha, John E. Chandler, Scott Gladstein, Biqin Dong, Cheng Sun, Hao F. Zhang, and Vadim Backman
MW2A.4 Microscopy Histopathology and Analytics (Microscopy) 2018

Imaging Nuclear Architecture at the Nanoscale for Cancer Detection and Prognosis

Yang Liu, Shikhar Uttam, Hoa V. Pham, Justin LaFace, and Douglas J. Hartman
OT1C.6 Bio-Optics: Design and Application (BODA) 2015

View More...
Partial wave spectroscopy and its relation to nanoscale disorder in nuclear architecture

Hariharan Subramanian, Dhwanil Damania, Krishnapal Solanki, Yolanda Stypula, Lusik Cherkezyan, Ashish Tiwari, Prabhakar Pradhan, Dhananjay Kunte, Hemant K. Roy, and Vadim Backman
BWB4 Biomedical Optics (BIOMED) 2010

Evaluating Nanoscale Chromatin Modifications for Risk Stratification of Colorectal Cancer using Machine Learning

Sravya Prabhala, Andrew S. Chang, Ali Daneshkhah, Hariharan Subramanian, Hemant Kumar Roy, and Vadim Backman
JTu4A.5 Bio-Optics: Design and Application (BODA) 2023

Select as filters
Select Topics Cancel
Top
       
© Copyright 2024 | Optica Publishing Group. All rights reserved, including rights for text and data mining and training of artificial technologies or similar technologies.
Privacy | Terms of Use