In this study, we develop an analytical based simulation method to determine laser parameters such as laser power and its duration for laser induced thermal ablation. This method utilizes two important physical approaches to model i) the light propagation and ii) the change in temperature due to the laser absorption in turbid media. First, the photon density is obtained analytically from the solution of the diffusion equation by deriving a special Greens’ function. Next, the Pennes bio-heat equation is solved analytically for a source term consisting of the product of the photon density and the optical absorption coefficient. Our approach is validated with the results obtained by Finite Element Method (FEM) and experimental results acquired from the gold-nanoparticle embedded phantom.

© 2018 The Author(s)

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